2023
Shared Lifestyle‐Related Risk Factors of Cardiovascular Disease and Cancer: Evidence for Joint Prevention
Masoudkabir F, Mohammadifard N, Mani A, Ignaszewski A, Davis M, Vaseghi G, Mansourian M, Franco C, Gotay C, Sarrafzadegan N. Shared Lifestyle‐Related Risk Factors of Cardiovascular Disease and Cancer: Evidence for Joint Prevention. The Scientific World JOURNAL 2023, 2023: 2404806. PMID: 37520844, PMCID: PMC10386903, DOI: 10.1155/2023/2404806.Peer-Reviewed Original Research
2022
Does Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer?
Masoudkabir F, Malekzadeh R, Yavari N, Zendehdel K, Mani A, Vasheghani-Farahani A, Ignaszewski A, Toma M, Roayaei P, Turk-Adawi K, Sarrafzadegan N. Does Opium Consumption Have Shared Impact on Atherosclerotic Cardiovascular Disease and Cancer? Archives Of Iranian Medicine 2022, 25: 50-63. PMID: 35128912, DOI: 10.34172/aim.2022.08.Peer-Reviewed Original ResearchConceptsAtherosclerotic cardiovascular diseaseRisk factorsOpium consumptionOpium abuseCardiovascular diseaseRisk of ASCVDLifestyle-related risk factorsASCVD risk factorsInadequate physical activityExcessive alcohol consumptionTypes of cancerKinds of cancersPotential carcinogenic effectsDiabetes mellitusPathophysiologic mechanismsOpium abusersUnhealthy dietPhysical activityCurrent evidenceAlcohol consumptionHeart attackCancerCarcinogenic effectsPoor controlDisease
2020
The role of Wnt signalling in development of coronary artery disease and its risk factors
Liu Y, Neogi A, Mani A. The role of Wnt signalling in development of coronary artery disease and its risk factors. Open Biology 2020, 10: 200128. PMID: 33081636, PMCID: PMC7653355, DOI: 10.1098/rsob.200128.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApoptosisBiomarkersCarrier ProteinsCell DifferentiationCell MovementCoronary Artery DiseaseDisease SusceptibilityEndotheliumGene Expression RegulationHumansLipid MetabolismMacrophage ActivationMacrophagesMyocytes, Smooth MuscleProtein BindingRisk FactorsWnt ProteinsWnt Signaling PathwayConceptsCoronary artery diseaseArtery diseaseRole of WntVascular smooth muscle cellsEndothelial cell dysfunctionReduced blood flowLow-density lipoproteinModified low-density lipoproteinWnt pathwaySmooth muscle cellsNon-canonical Wnt/CaAggregation of monocytesTissue-resident macrophagesChest painEndothelial dysfunctionWnt/CaHeart failureLuminal narrowingCascade of eventsPathophysiological mechanismsMyocardial infarctionRisk factorsHeart diseaseCell dysfunctionInflammatory reaction
2015
New targets to treat obesity and the metabolic syndrome
Martin KA, Mani MV, Mani A. New targets to treat obesity and the metabolic syndrome. European Journal Of Pharmacology 2015, 763: 64-74. PMID: 26001373, PMCID: PMC4573317, DOI: 10.1016/j.ejphar.2015.03.093.Peer-Reviewed Original ResearchConceptsMetabolic syndromeCardiovascular diseaseGlucagon-like peptide-1 receptor agonistsPancreatic lipase inhibitor orlistatSingle CVD risk factorPeptide-1 receptor agonistsCVD risk factorsEpidemic of obesityLong-term treatmentType 2 diabetesLipase inhibitor orlistatDipeptidyl peptidase IV inhibitorsAnti-diabetic drugsFuture drug developmentTruncal obesitySerotonergic drugsReceptor agonistRisk factorsMelanocortin systemObesityMetabolic traitsSyndromeMetabolic profileIV inhibitorsNew targets
2012
Prevalence of Obesity and Traditional Cardiovascular Risk Factors in South Asians
Khanna P, Mani A. Prevalence of Obesity and Traditional Cardiovascular Risk Factors in South Asians. Current Cardiovascular Risk Reports 2012, 6: 112-119. DOI: 10.1007/s12170-012-0220-x.Peer-Reviewed Original ResearchRisk factorsCardiovascular diseaseSouth AsiansTraditional cardiovascular risk factorsCardiovascular risk factorsCVD risk factorsPrevalence of obesityLifestyle factorsNovel biomarkersGenetic predispositionHealthcare providersDisease controlNovel therapeuticsMajor causeGenetic causePrevalenceObesityWestern worldAsiansCauseImportant contributorDiabetesSpecific differencesFactorsMortality