1990
Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification
Summers J, Smith P, Horwich A. Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification. Journal Of Virology 1990, 64: 2819-2824. PMID: 2335817, PMCID: PMC249463, DOI: 10.1128/jvi.64.6.2819-2824.1990.Peer-Reviewed Original ResearchConceptsCccDNA synthesisEnvelope proteinVirus-mediated cell deathHepadnavirus envelope proteinsCircular DNA amplificationViral DNA synthesisWild-type virusWild typeViral envelope proteinsCell deathCircular DNAPrimary duck hepatocytesDNA synthesisProteinDNA amplificationPersistent infectionDuck hepatocytesSynthesis of hepadnavirus particles that contain replication-defective duck hepatitis B virus genomes in cultured HuH7 cells
Horwich A, Furtak K, Pugh J, Summers J. Synthesis of hepadnavirus particles that contain replication-defective duck hepatitis B virus genomes in cultured HuH7 cells. Journal Of Virology 1990, 64: 642-650. PMID: 2153230, PMCID: PMC249155, DOI: 10.1128/jvi.64.2.642-650.1990.Peer-Reviewed Original ResearchConceptsHepatitis B virus genomeDirect repeat 1Duck hepatitis B virus genomesInfectious virusViral DNA synthesisVirus antigen productionCore antigenDNA-containing viral particlesHepatoma cell line Huh7Human hepatoma cell line Huh7Cultured Huh7 cellsDNA synthesisVirus genomeAntigen productionHuh7 cellsEnvelope proteinViral particlesLoss of abilityViral DNA
1983
Expression and Stabilization of Microinjected Plasmids Containing the Herpes Simplex Virus Thymidine Kinase Gene and Polyoma Virus DNA in Mouse Cells
Yamaizumi M, Horwich A, Ruddle F. Expression and Stabilization of Microinjected Plasmids Containing the Herpes Simplex Virus Thymidine Kinase Gene and Polyoma Virus DNA in Mouse Cells. Molecular And Cellular Biology 1983, 3: 511-522. PMID: 6304496, PMCID: PMC368567, DOI: 10.1128/mcb.3.4.511.Peer-Reviewed Original Research