THE EFFECTS OF EARLY TREATMENT OF HEREDITARY TYROSINEMIA TYPE I IN INFANCY BY ORTHOTOPIC LIVER TRANSPLANTATION
Flye M, RIELY C, HAINLINE B, SASSA S, GUSBERG R, BLAKEMORE K, BARWICK K, HORWICH A. THE EFFECTS OF EARLY TREATMENT OF HEREDITARY TYROSINEMIA TYPE I IN INFANCY BY ORTHOTOPIC LIVER TRANSPLANTATION. Transplantation 1990, 49: 916-921. PMID: 2336709, DOI: 10.1097/00007890-199005000-00017.Peer-Reviewed Original ResearchConceptsOrthotopic liver transplantationLiver transplantationMedical therapyHereditary tyrosinemiaEarly liver transplantationMinimal perioperative complicationsWeeks of ageTyrosinemia type IPerioperative complicationsRapid institutionPoor prognosisNormal dietEarly treatmentMetabolic disordersTransplantationPrompt clearanceAbnormal metabolitesHydrolase deficiencyInfantsMental alertnessProgressive growthTherapyType ITyrosinemiaBiochemical responses