1997
Chaperonin-Mediated Folding in the Eukaryotic Cytosol Proceeds through Rounds of Release of Native and Nonnative Forms
Farr G, Scharl E, Schumacher R, Sondek S, Horwich A. Chaperonin-Mediated Folding in the Eukaryotic Cytosol Proceeds through Rounds of Release of Native and Nonnative Forms. Cell 1997, 89: 927-937. PMID: 9200611, DOI: 10.1016/s0092-8674(00)80278-0.Peer-Reviewed Original ResearchConceptsRounds of releaseSubstrate proteinsNonnative formsNative formChaperonin-mediated foldingEukaryotic cytosolic chaperoninATP-dependent foldingIntact Xenopus oocytesCytosolic chaperoninBacterial chaperoninsEukaryotic cytosolChaperoninNative stateXenopus oocytesEssential roleSingle roundFoldingProteinActinTubulinOverall mechanismGroELTransducinCytosolSmall fraction
1996
5 Structure and Function of Chaperonins in Archaebacteria and Eukaryotic Cytosol
Willison K, Horwich A. 5 Structure and Function of Chaperonins in Archaebacteria and Eukaryotic Cytosol. 1996, 107-136. DOI: 10.1016/b978-012237455-5/50006-3.Peer-Reviewed Original ResearchChaperonin-containing TCP-1Eukaryotic cytosolEukaryotic cellsTCP-1Protein foldingUnfolded proteinsChaperoninCytoskeletal proteinsSubunit speciesFunctional analysisGeneral functionProteinArchaebacteriaGeneral affinityCytosolFoldingSpecific affinityGenesSpeciesAffinityActinTubulinFunctionCellsUnusual type