2021
Macroscopic Structural and Connectome Mapping of the Mouse Brain Using Diffusion Magnetic Resonance Imaging
Arefin TM, Lee CH, White JD, Zhang J, Kaffman A. Macroscopic Structural and Connectome Mapping of the Mouse Brain Using Diffusion Magnetic Resonance Imaging. Bio-protocol 2021, 11: e4221. PMID: 34909442, PMCID: PMC8635841, DOI: 10.21769/bioprotoc.4221.Peer-Reviewed Original ResearchEarly life stressMagnetic resonance imagingMouse brainDiffusion magnetic resonance imagingMouse modelResonance imagingWhole-brain voxel-based analysisVoxel-based analysisClinical trialsPostnatal stressPreclinical studiesNeurological conditionsAdult miceEntire mouse brainStructural abnormalitiesBrain regionsMouse strainsBrain connectivityBrainLife stressTranslational utilityStructural connectivityRodentsMiceTranslational work
2020
Early life stress causes sex-specific changes in adult fronto-limbic connectivity that differentially drive learning
White JD, Arefin TM, Pugliese A, Lee CH, Gassen J, Zhang J, Kaffman A. Early life stress causes sex-specific changes in adult fronto-limbic connectivity that differentially drive learning. ELife 2020, 9: e58301. PMID: 33259286, PMCID: PMC7725504, DOI: 10.7554/elife.58301.Peer-Reviewed Original ResearchConceptsEarly life stressSex-specific changesContextual freezing behaviorFronto-limbic connectivityLife stressHigh-resolution diffusion magnetic resonance imagingSex-specific mechanismsMagnetic resonance imagingNeuroanatomical alterationsPostnatal stressDiffusion magnetic resonance imagingMouse modelFronto-limbicResonance imagingModerate responseMalesTranslational workFemalesRodentsFreezing behaviorHuman imagingImagingHypoconnectivityInjury