Metabolic decisions in development and disease—a Keystone Symposia report
Cable J, Pourquié O, Wellen K, Finley L, Aulehla A, Gould A, Teleman A, Tu W, Garrett W, Miguel‐Aliaga I, Perrimon N, Hooper L, Walhout A, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz J, Hemalatha A, Gutiérrez‐Pérez P, Chandel N, Rutter J, Locasale J, Landoni J, Christofk H. Metabolic decisions in development and disease—a Keystone Symposia report. Annals Of The New York Academy Of Sciences 2021, 1506: 55-73. PMID: 34414571, DOI: 10.1111/nyas.14678.Peer-Reviewed Original ResearchConceptsMetabolic decisionsProtein post-translational modificationsCell decision makingPost-translational modificationsKeystone Symposia reportCell-type specificPrecise metabolic controlDevelopmental decisionsCell fateDevelopmental biologyKeystone eSymposiumCell signalingAllosteric mechanismCell statesProtein activityGene expressionEpigenetic markersMetabolic enzymesCell metabolismRole of metabolismHuman diseasesMetabolic pathwaysNormal developmentEnzyme activityModel system