2017
Dynamic contrast‐enhanced MRI perfusion for differentiating between melanoma and lung cancer brain metastases
Hatzoglou V, Tisnado J, Mehta A, Peck KK, Daras M, Omuro AM, Beal K, Holodny AI. Dynamic contrast‐enhanced MRI perfusion for differentiating between melanoma and lung cancer brain metastases. Cancer Medicine 2017, 6: 761-767. PMID: 28303695, PMCID: PMC5387174, DOI: 10.1002/cam4.1046.Peer-Reviewed Original ResearchConceptsMelanoma brain metastasesNSCLC brain metastasesLung cancer brain metastasesBrain metastasesCancer brain metastasesCell lung cancer brain metastasesDCE-MRIPrimary brain tumorsDifferent primary sitesImportant clinical implicationsMann-Whitney U testVolume transfer coefficientTumor histologyMultiple malignanciesMRI perfusionBrain tumorsMetastasisPrimary siteConventional MRIClinical implicationsPerfusion parametersTumor microvasculatureROC analysisU testPlasma volume
2016
Diagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced–MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS Lymphoma
Lin X, Lee M, Buck O, Woo K, Zhang Z, Hatzoglou V, Omuro A, Arevalo-Perez J, Thomas A, Huse J, Peck K, Holodny A, Young R. Diagnostic Accuracy of T1-Weighted Dynamic Contrast-Enhanced–MRI and DWI-ADC for Differentiation of Glioblastoma and Primary CNS Lymphoma. American Journal Of Neuroradiology 2016, 38: 485-491. PMID: 27932505, PMCID: PMC5352508, DOI: 10.3174/ajnr.a5023.Peer-Reviewed Original Research
2011
Potential utility of conventional MRI signs in diagnosing pseudoprogression in glioblastoma
Young R, Gupta A, Shah A, Graber J, Zhang Z, Shi W, Holodny A, Omuro A. Potential utility of conventional MRI signs in diagnosing pseudoprogression in glioblastoma. Neurology 2011, 76: 1918-1924. PMID: 21624991, PMCID: PMC3115805, DOI: 10.1212/wnl.0b013e31821d74e7.Peer-Reviewed Original ResearchConceptsEarly progressionMRI signsNegative predictive valuePredictive valueFinal diagnosisHigh negative predictive valueUseful MRI markerFisher's exact testSubependymal spreadSecond resectionRetrospective studyMass lesionSurgical specimensMRI markersPotential utilityClinical physiciansExact testMRI scansPatientsSubependymal enhancementLesionsGlioblastomaPseudoprogressionSignsDiagnosis