2024
Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination
Vesco K, Denoble A, Lipkind H, Kharbanda E, DeSilva M, Daley M, Getahun D, Zerbo O, Naleway A, Jackson L, Williams J, Boyce T, Fuller C, Weintraub E, Vazquez-Benitez G. Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination. Obstetrics And Gynecology 2024, 143: 794-802. PMID: 38626447, PMCID: PMC11090513, DOI: 10.1097/aog.0000000000005583.Peer-Reviewed Original ResearchConceptsSmall-for-gestational ageMessenger RNA COVID-19 vaccineGestational diabetes mellitusRisk of adverse pregnancy outcomesAdverse pregnancy outcomesPreterm birthGestational hypertensionAdjusted hazard ratiosCOVID-19 vaccine dosesPregnancy outcomesCOVID-19 vaccineAssociated with small-for-gestational ageIncreased risk of adverse pregnancy outcomesVaccine doseRisk of preterm birthMessenger RNARetrospective cohort study of individualsMRNA COVID-19 vaccineWeeks of gestationRetrospective cohort studyHistory of COVID-19Cohort study of individualsVaccine Safety DatalinkSingleton pregnanciesUnexposed pregnanciesRate of clinically significant red blood cell antibody seroconversion in pregnancy
Ding J, Abels E, Jacobs J, Culhane J, Lundsberg L, Partridge C, Denoble A, Kohari K. Rate of clinically significant red blood cell antibody seroconversion in pregnancy. The Journal Of Maternal-Fetal & Neonatal Medicine 2024, 37: 2419370. PMID: 39462637, DOI: 10.1080/14767058.2024.2419370.Peer-Reviewed Original ResearchConceptsNeonatal intensive care unitAdvanced maternal ageAssociated with seroconversionClinically significant antibodiesAntibody screeningNeonatal outcomesIncreasing gravidityAntibody seroconversionInitial hemoglobinMaternal ageSignificant antibodiesAntibody statusNeonatal intensive care unit admissionCohort studyClinically significant RBC antibodiesAnti-CUnexplained fetal lossPositive antibody screenNegative antibody screenCases of stillbirthRetrospective cohort studyIntensive care unitWilcoxon rank-sumMaternal antibody statusPostnatal transfusion
2021
Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes
Wu J, Denoble AE, Kuller JA, Dotters-Katz SK. Management of Cerclage in Patients With Preterm Prelabor Rupture of Membranes. Obstetrical & Gynecological Survey 2021, 76: 681-691. PMID: 34854925, DOI: 10.1097/ogx.0000000000000957.Peer-Reviewed Original ResearchConceptsMaternal infectious morbidityPreterm prelabor ruptureCerclage removalCervical cerclageInfectious morbidityNeonatal outcomesPrelabor ruptureNeonatal morbidity outcomesRetention of cerclageSetting of PPROMTime of PPROMTime of diagnosisCerclage placementCerclage retentionLatency antibioticsNeonatal complicationsCorticosteroid administrationMaternal morbidityPreterm laborNeonatal sepsisMorbidity outcomesNeonatal mortalityRetrospective natureDefinitive benefitPPROMPregnancy outcomes among women with class III obesity with normal early glucola
Ellett T, Mitchell CJ, Dillon J, Siegel A, Denoble AE, Dotters-Katz S. Pregnancy outcomes among women with class III obesity with normal early glucola. The Journal Of Maternal-Fetal & Neonatal Medicine 2021, 35: 5834-5839. PMID: 33818267, DOI: 10.1080/14767058.2021.1895741.Peer-Reviewed Original ResearchConceptsBody mass indexRate of GDMGlucose challenge testGestational diabetesObese womenPrimary outcomeGestational ageChallenge testDelivery body mass indexNon-anomalous singleton pregnanciesMaternal body mass indexOral glucose challenge testClass 3 obesityDevelopment of GDMClass III obesityGestational diabetes mellitusFetal growth restrictionInduction of laborNeonatal birthweightPregnancy complicationsBaseline demographicsCesarean deliveryMultiple gestationsPregnancy outcomesRetrospective cohort
2020
Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis?
Rosett HA, Krischak MK, Sachdeva S, Weaver KE, Heine RP, Denoble AE, Dotters-Katz SK. Lower Urinary Pathogens: Do More Pathogenic Bacteria Increase the Risk of Pyelonephritis? American Journal Of Perinatology 2020, 39: 473-478. PMID: 32971563, DOI: 10.1055/s-0040-1717093.Peer-Reviewed Original ResearchConceptsLower urinary tract infectionsHistory of preeclampsiaPreterm birthPregnant womenLow birthweightPathogenic infectionsOutside of pregnancyRisk of pyelonephritisOdds of progressionSingle tertiary centerPreterm birth rateRisk of progressionUrinary tract infectionBody mass indexRate of progressionHistory of pyelonephritisAsymptomatic bacteriuriaChronic hypertensionMedian LOSObstetric outcomesUrinary culturePostpartum dataRetrospective cohortSecondary outcomesTract infectionsChorioamnionitis versus intraamniotic infection among preterm deliveries—is postpartum infectious morbidity different?
Denoble AE, Wu J, Mitchell CJ, Hughes BL, Dotters-Katz SK. Chorioamnionitis versus intraamniotic infection among preterm deliveries—is postpartum infectious morbidity different? American Journal Of Obstetrics & Gynecology MFM 2020, 2: 100176. PMID: 33345890, DOI: 10.1016/j.ajogmf.2020.100176.Peer-Reviewed Original ResearchMeSH KeywordsChorioamnionitisEndometritisFemaleHumansInfant, NewbornMorbidityPostpartum PeriodPregnancyPuerperal InfectionConceptsPostpartum infectious morbidityIntraamniotic infectionClinical chorioamnionitisPostpartum endometritisAntibiotic treatmentMaternal temperatureAmerican CollegeInfectious morbidityPreterm deliveryPotential confoundersGynecologists criteriaAdditional clinical risk factorsAntenatal magnesium sulfateIntrapartum antibiotic treatmentPostpartum endometritis ratePostpartum infectious complicationsClinical risk factorsMultivariate logistic regressionOriginal study populationProportion of womenEndometritis ratesFetal morbidityInfectious complicationsPreterm birthPrimary outcome
2019
Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention
Wheeler S, DeNoble A, Wynn C, Weaver K, Swamy G, Janko M, Lantos P. Beyond the Window: Patient Characteristics and Geographic Locations Associated with Late Prenatal Care in Women Eligible for 17-P Preterm Birth Prevention. Journal Of Racial And Ethnic Health Disparities 2019, 6: 563-569. PMID: 30632084, DOI: 10.1007/s40615-018-00555-8.Peer-Reviewed Original ResearchConceptsLate presentationPreterm birthGestational ageSingle academic medical centerPatient-level risk factorsIndex pregnancy outcomeRisk of presentationMean gestational agePreterm birth preventionRetrospective cohort studySpontaneous preterm birthLate prenatal careYoung maternal ageRisk of recurrenceWeeks of pregnancyLater gestational agesEarly prenatal care initiationPrenatal care initiationAcademic medical centerBirth preventionCohort studyCurrent smokingLate presentersPatient characteristicsPregnancy outcomes
2015
Controversies in the Management of Isolated Congenital Atrioventricular Block
DeNoble AE, Kuller JA, Rhee EJ. Controversies in the Management of Isolated Congenital Atrioventricular Block. Obstetrical & Gynecological Survey 2015, 70: 518-523. PMID: 26314237, DOI: 10.1097/ogx.0000000000000208.Peer-Reviewed Original ResearchConceptsCongenital atrioventricular blockAnti-La antibodiesAtrioventricular blockIntravenous immunoglobulinFetuses of mothersStudy of dexamethasoneTreatment of fetusesLarge prospective studiesHigh fetal morbidityPotential adverse effectsRheumatologic symptomsAnti-RoFetal morbidityAntinuclear antibodiesFetal hydropsProspective studyTreatment regimensAutoimmune diseasesRisk mothersLimited potential benefitsAdverse effectsFetusesConflicting resultsAntibodiesTreatment