2005
Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors
Liu X, Wang Q, Haydar TF, Bordey A. Nonsynaptic GABA signaling in postnatal subventricular zone controls proliferation of GFAP-expressing progenitors. Nature Neuroscience 2005, 8: 1179-1187. PMID: 16116450, PMCID: PMC1380263, DOI: 10.1038/nn1522.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBotulinum ToxinsBromodeoxyuridineCadmiumCell CountCell ProliferationChelating AgentsCyclooxygenase InhibitorsDose-Response Relationship, DrugDose-Response Relationship, RadiationDrug InteractionsEgtazic AcidElectric StimulationEnzyme InhibitorsGABA AntagonistsGamma-Aminobutyric AcidGene Expression RegulationGlial Fibrillary Acidic ProteinGreen Fluorescent ProteinsImmunohistochemistryIn Vitro TechniquesLateral VentriclesMeclofenamic AcidMembrane PotentialsMiceMice, TransgenicNeuronsNickelPatch-Clamp TechniquesPotassiumSodium Channel BlockersSpider VenomsStem CellsTetrodotoxinConceptsPostnatal subventricular zoneGFAP-expressing cellsSubventricular zoneCell cycleGABAA receptorsStem cellsNeuroblastsProgenitorsGlial fibrillary acidic proteinSVZ cellsGABAA receptor currentsGABAA receptor activationFibrillary acidic proteinReceptor activationCellsProliferationGABA releaseMouse slicesLocal cuesAcidic proteinReceptor currentsSpontaneous depolarizationsGFAPGABAReceptors
1998
Electrophysiological Properties of Human Astrocytic Tumor Cells In Situ: Enigma of Spiking Glial Cells
Bordey A, Sontheimer H. Electrophysiological Properties of Human Astrocytic Tumor Cells In Situ: Enigma of Spiking Glial Cells. Journal Of Neurophysiology 1998, 79: 2782-2793. PMID: 9582244, DOI: 10.1152/jn.1998.79.5.2782.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAstrocytesAstrocytomaBrain NeoplasmsCarcinomaCell DifferentiationChildChoroid Plexus NeoplasmsDelayed Rectifier Potassium ChannelsHumansIon TransportNeoplasm ProteinsNeoplastic Stem CellsNerve Tissue ProteinsPatch-Clamp TechniquesPotassiumPotassium Channel BlockersPotassium ChannelsPotassium Channels, Inwardly RectifyingPotassium Channels, Voltage-GatedSodium Channel BlockersSodium ChannelsSpinal CordTetraethylammoniumTetrodotoxinConceptsAstrocytoma cellsTumor cellsGlial cellsWhole-cell patch-clamp recordingsCell patch-clamp recordingsAction potential-like responsesOlder pediatric patientsSpinal cord astrocytesHuman astrocytic tumor cellsSensitive sodium currentsGroup of tumorsLow-grade astrocytomasPatch-clamp recordingsOutward potassium currentGlial tumor cellsAstrocytic tumor cellsGeneration of spikesHigh input resistancePeritumoral astrocytesPediatric patientsMicroM Ba2Pilocytic astrocytomaPotassium currentAstrocytesElectrophysiological properties