2015
PreImplantation Factor bolsters neuroprotection via modulating Protein Kinase A and Protein Kinase C signaling
Mueller M, Schoeberlein A, Zhou J, Joerger-Messerli M, Oppliger B, Reinhart U, Bordey A, Surbek D, Barnea ER, Huang Y, Paidas M. PreImplantation Factor bolsters neuroprotection via modulating Protein Kinase A and Protein Kinase C signaling. Cell Death & Differentiation 2015, 22: 2078-2086. PMID: 25976303, PMCID: PMC4816111, DOI: 10.1038/cdd.2015.55.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBcl-Associated Death ProteinBrain InjuriesCell Line, TumorCell SurvivalCyclic AMPCyclic AMP Response Element-Binding ProteinCyclic AMP-Dependent Protein KinasesDisease Models, AnimalGAP-43 ProteinMiceMicroRNAsNeuroprotective AgentsPeptidesProtein Kinase CProto-Oncogene Proteins c-bcl-2RatsRNA InterferenceSignal TransductionToll-Like Receptor 4ConceptsPreImplantation FactorCentral nervous system damageExperimental autoimmune encephalomyelitisPerinatal brain injuryBrain injury modelNervous system damageExpression of GAP43Autoimmune encephalomyelitisTLR4 expressionNeuronal lossPotential clinical applicationsCNS diseaseNeuronal deathBrain injuryClinical trialsInjury modelFast-track approvalProtective effectRodent modelsGAP-43NeuroprotectionSystem damageNeuronal growthProtein kinaseCortical architecture
2000
Reactive astrocytes show enhanced inwardly rectifying K+ currents in situ
Bordey A, Hablitz JJ, Sontheimer H. Reactive astrocytes show enhanced inwardly rectifying K+ currents in situ. Neuroreport 2000, 11: 3151-3155. PMID: 11043540, DOI: 10.1097/00001756-200009280-00022.Peer-Reviewed Original Research