2013
Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex
Feliciano DM, Zhang S, Quon JL, Bordey A. Hypoxia-inducible factor 1a is a Tsc1-regulated survival factor in newborn neurons in tuberous sclerosis complex. Human Molecular Genetics 2013, 22: 1725-1734. PMID: 23349360, PMCID: PMC3613161, DOI: 10.1093/hmg/ddt018.Peer-Reviewed Original ResearchConceptsHypoxia-inducible factor 1aTuberous sclerosis complexShort hairpin RNANewborn neuronsFactor 1ASubventricular zoneSVZ stem cellsNewborn neuron survivalNeurogenic subventricular zoneSingle-cell electroporationTranscriptional activityShRNA expressionHairpin RNAMammalian targetMolecular determinantsNovel microenvironmentNeuron deathNeuron survivalOlfactory lesionsNeonatal miceBrain lesionsStem cellsMouse modelNeuron productionSurvival advantage
2006
Nonsynaptic GABAergic Communication and Postnatal Neurogenesis
Liu X, Bolteus A, Bordey A. Nonsynaptic GABAergic Communication and Postnatal Neurogenesis. Contemporary Neuroscience 2006, 95-104. DOI: 10.1007/978-1-59745-021-8_9.ChaptersFunction of GABASubventricular zonePostnatal neurogenesisNeuronal precursorsNeuron-glial networksSVZ stem cellsStem cellsNeural stem cellsLocal GABAergicNonsynaptic communicationGABAergic systemSynaptic contactsΓ-aminobutyric acidSVZ cellsSVZ precursorsSubependymal zoneGABANeurogenesisCell proliferationCellsEmbryonic cell proliferationGABAergicBrain