2001
Electrophysiological Characteristics of Reactive Astrocytes in Experimental Cortical Dysplasia
Bordey A, Lyons SA, Hablitz JJ, Sontheimer H. Electrophysiological Characteristics of Reactive Astrocytes in Experimental Cortical Dysplasia. Journal Of Neurophysiology 2001, 85: 1719-1731. PMID: 11287494, DOI: 10.1152/jn.2001.85.4.1719.Peer-Reviewed Original ResearchConceptsGap junction couplingReactive gliosisFreeze lesionGlial fibrillary acidic protein immunoreactivityWhole-cell patch-clamp recordingsCell patch-clamp recordingsExperimental cortical dysplasiaCortical layers IPatch-clamp recordingsPostnatal day 16Reduced gap junction couplingNormal neuronal functionDysplastic neocortexP24 ratsDysplastic cortexReactive astrocytesCortical dysplasiaNeuronal dysfunctionProtein immunoreactivityElectrophysiological characteristicsAstrocytesChannel expressionNeuronal functionMicrosulcusLayer I
2000
Reactive astrocytes show enhanced inwardly rectifying K+ currents in situ
Bordey A, Hablitz JJ, Sontheimer H. Reactive astrocytes show enhanced inwardly rectifying K+ currents in situ. Neuroreport 2000, 11: 3151-3155. PMID: 11043540, DOI: 10.1097/00001756-200009280-00022.Peer-Reviewed Original Research