Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonates
Silbereis J, Heintz T, Taylor MM, Ganat Y, Ment LR, Bordey A, Vaccarino F. Astroglial cells in the external granular layer are precursors of cerebellar granule neurons in neonates. Molecular And Cellular Neuroscience 2010, 44: 362-373. PMID: 20470892, PMCID: PMC2900521, DOI: 10.1016/j.mcn.2010.05.001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAstrocytesBasic Helix-Loop-Helix Transcription FactorsBeta-GalactosidaseCell LineageCerebellumGenes, ReporterGlial Fibrillary Acidic ProteinGreen Fluorescent ProteinsIntegrasesMiceMice, Inbred C57BLMice, TransgenicNeurogenesisNeuronsPromoter Regions, GeneticStem CellsTime FactorsConceptsExternal granule cell layerGranule cell precursorsInternal granule cell layerGranule cell layerGranule cellsRhombic lipAstroglial cellsProtein expression profilesGlial fibrillary acidic protein promoterCerebellar granule cell precursorsHuman glial fibrillary acidic protein promoterEmbryonic rhombic lipInducible Cre recombinaseNeuronal progenitor cellsReporter proteinFirst postnatal weekNeural stem cell markersLate embryogenesisCellular plasticityImmature granule cellsEarly postnatal developmentCell layerReporter geneCerebellar granule neuronsStem cell markersGABAA Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels
Young SZ, Platel JC, Nielsen JV, Jensen NA, Bordey A. GABAA Increases Calcium in Subventricular Zone Astrocyte-Like Cells Through L- and T-Type Voltage-Gated Calcium Channels. Frontiers In Cellular Neuroscience 2010, 4: 8. PMID: 20422045, PMCID: PMC2857959, DOI: 10.3389/fncel.2010.00008.Peer-Reviewed Original ResearchVoltage-gated calcium channelsT-type voltage-gated calcium channelsAstrocyte-like cellsSubventricular zoneReceptor activationCalcium channelsFunctional voltage-gated calcium channelsChannel activator BayK 8644Glial fibrillary acidic protein promoterHuman glial fibrillary acidic protein promoterNeurogenic subventricular zonePostnatal subventricular zoneAcidic protein promoterAmbient GABABayK 8644Transgenic miceReceptor activityL-typeProtein promoterReceptorsTonicActivationCellsIntracellularMibefradil