2009
Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells
Genzen JR, Yang D, Ravid K, Bordey A. Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells. Fluids And Barriers Of The CNS 2009, 6: 15. PMID: 19922651, PMCID: PMC2791093, DOI: 10.1186/1743-8454-6-15.Peer-Reviewed Original ResearchEpendymal cellsCiliary beat frequencyPurinergic receptorsCerebrospinal fluidA2B receptor activationReceptor activationP2X7-/- micePurinergic receptor subtypesAdenosine A2B receptorAdenosine receptor agonistsMetabolic breakdown productsCalcium imaging experimentsCerebrospinal fluid dynamicsA2B expressionFlow of CSFBrain parenchymaReceptor agonistPurinergic agentsReceptor subtypesAirway epitheliumFluid balancePharmacological approachesVentricular systemKnockout miceA2B receptors
2000
Muscarinic Activation of BK Channels Induces Membrane Oscillations in Glioma Cells and Leads to Inhibition of Cell Migration
Bordey A, Sontheimer H, Trouslard J. Muscarinic Activation of BK Channels Induces Membrane Oscillations in Glioma Cells and Leads to Inhibition of Cell Migration. The Journal Of Membrane Biology 2000, 176: 31-40. PMID: 10882426, DOI: 10.1007/s00232001073.Peer-Reviewed Original ResearchConceptsPatch-clamp recordingsGlioma cellsAstrocytoma cellsCell migrationCultured human astrocytoma cellsIntracellular free calcium concentrationACh receptor agonistsFree calcium concentrationHuman astrocytoma cellsRelease of Ca2Glioma cell migrationMuscarinic activationMuscarinic antagonistCerebral tumorsMuscarinic receptorsReceptor agonistBath applicationActivate Ca2Intracellular injectionCerebrospinal fluidACh applicationAcetylcholineBiphasic increaseIntracellular storesExternal calcium