Lactobacillus rhamnosus GR-1-Induced IL-10 Production in Human Placental Trophoblast Cells Involves Activation of JAK/STAT and MAPK Pathways
Yeganegi M, Leung C, Martins A, Kim S, Reid G, Challis J, Bocking A. Lactobacillus rhamnosus GR-1-Induced IL-10 Production in Human Placental Trophoblast Cells Involves Activation of JAK/STAT and MAPK Pathways. Reproductive Sciences 2010, 17: 1043-1051. PMID: 20858906, DOI: 10.1177/1933719110377237.Peer-Reviewed Original ResearchConceptsHuman placental trophoblast cellsPlacental trophoblast cellsPreterm birthEnzyme-linked immunosorbent assayRhamnosus GR-1Gr-1Trophoblast cellsIntrauterine infection/inflammationAnti-inflammatory effectsIL-10 productionInfection/inflammationWestern blot analysisHealthy pregnancyPhosphorylation of STAT3IL-10Janus kinase/signal transducerJAK/STATCytokine regulationKinase/signal transducerPotential preventionPlacental trophoblastsMitogen-activated protein kinase pathwayAbsence of pretreatmentHuman placentaSTAT-3