2022
Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Primary Spinal Intradural/Cord Tumors
Elsamadicy AA, Koo AB, Reeves BC, Pennington Z, Sarkozy M, Hersh A, Havlik J, Sherman JJZ, Goodwin CR, Kolb L, Laurans M, Lo S, Shin JH, Sciubba DM. Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Primary Spinal Intradural/Cord Tumors. Global Spine Journal 2022, 13: 2074-2084. PMID: 35016582, PMCID: PMC10556884, DOI: 10.1177/21925682211069937.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreNon-routine dischargeFrailty Risk ScoreImpact of frailtyCost of admissionDischarge dispositionFrail cohortPrimary tumorSpinal cordRisk scoreNationwide Inpatient Sample databaseRetrospective cohort studyHealthcare resource utilizationLength of stayPrimary spinal tumorsGreater mean costICD-10 codesICD-10-CM codesLarge national datasetPerioperative complicationsPostoperative complicationsAdult patientsCohort studyLonger LOSPatient characteristics
2021
Impact of Racial Disparities on All-Cause Mortality in Patients With Tumors of the Spinal Cord or Spinal Meninges: A Propensity-Score Analysis
Elsamadicy AA, Freedman I, Koo AB, David WB, Reeves BC, Hengartner A, Pennington Z, Laurans M, Kolb L, Shin JH, Sciubba D. Impact of Racial Disparities on All-Cause Mortality in Patients With Tumors of the Spinal Cord or Spinal Meninges: A Propensity-Score Analysis. Global Spine Journal 2021, 13: 1365-1373. PMID: 34318727, PMCID: PMC10416582, DOI: 10.1177/21925682211033827.Peer-Reviewed Original ResearchSpinal cordCause mortalitySpinal meningesNonmalignant tumorsCox proportional hazards regression analysisProportional hazards regression analysisIntradural spine tumorsReceipt of RTOutcomes of patientsRetrospective cohort studyEnd Results registryKaplan-Meier methodOverall survival estimatesSpinal cord tumorsAssociation of survivalLog-rank testAfrican American patientsPopulation-based estimatesPropensity score analysisPropensity-score matchingCohort studyCord tumorsSpine tumorsWhite patientsAnalysis ageHypermutated phenotype in gliosarcoma of the spinal cord
Hong CS, Kuzmik GA, Kundishora AJ, Elsamadicy AA, Koo AB, McGuone D, Blondin NA, DiLuna ML, Erson-Omay EZ. Hypermutated phenotype in gliosarcoma of the spinal cord. Npj Precision Oncology 2021, 5: 8. PMID: 33580181, PMCID: PMC7881101, DOI: 10.1038/s41698-021-00143-w.Peer-Reviewed Original ResearchSpinal cordWhole-exome sequencingLow-grade brain gliomasVariant of glioblastomaLow-grade gliomasTumor anteriorAdjuvant radiationNeurological deficitsSomatic single nucleotide variationsPoor prognosisGrade gliomasTemozolomide treatmentBrain gliomasGliosarcomaMicrosatellite stabilityCordSomatic mutationsHypermutator phenotypeGliomasComprehensive genetic characterizationGenomic mechanismsSingle nucleotide variationsPhenotypeFirst reportPathway genes
2020
Race and All-cause Mortality in Patients with a Primary Malignant or Nonmalignant Tumor of the Spinal Cord or Spinal Meninges
Elsamadicy A, Freedman I, Koo A, David W, Reeves B, Antonios J, Laurans M, Kolb L, Sciubba D. Race and All-cause Mortality in Patients with a Primary Malignant or Nonmalignant Tumor of the Spinal Cord or Spinal Meninges. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_203.Peer-Reviewed Original Research