2019
Comparison of the prevalence, severity, and risk factors for hepatic steatosis in HIV-infected and uninfected people
Torgersen J, So-Armah K, Freiberg MS, Goetz MB, Budoff MJ, Lim JK, Taddei T, Butt AA, Rodriguez-Barradas MC, Justice AC, Kostman JR, Lo Re V. Comparison of the prevalence, severity, and risk factors for hepatic steatosis in HIV-infected and uninfected people. BMC Gastroenterology 2019, 19: 52. PMID: 30987601, PMCID: PMC6466708, DOI: 10.1186/s12876-019-0969-1.Peer-Reviewed Original ResearchConceptsAdvanced hepatic fibrosisSeverity of steatosisHepatic steatosisHIV infectionHIV statusHepatic fibrosisLiver attenuationCardiovascular diseaseSteatosis severityUninfected individualsGreater severityVeterans Aging Cohort StudyNoncontrast abdominal CTAging Cohort StudySpleen attenuation ratioHepatic steatosis severityCross-sectional studyMultivariable linear regressionUninfected participantsAntiretroviral therapyCohort studyAbdominal CTUninfected personsOverall prevalenceRisk factors
2018
Markers of chronic obstructive pulmonary disease are associated with mortality in people living with HIV
Triplette M, Justice A, Attia EF, Tate J, Brown ST, Goetz MB, Kim JW, Rodriguez-Barradas MC, Hoo GWS, Wongtrakool C, Akgün K, Crothers K. Markers of chronic obstructive pulmonary disease are associated with mortality in people living with HIV. AIDS 2018, 32: 487-493. PMID: 29135579, PMCID: PMC6366454, DOI: 10.1097/qad.0000000000001701.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersFemaleHIV InfectionsHumansLongitudinal StudiesLungMaleMiddle AgedPulmonary Disease, Chronic ObstructiveRespiratory Function TestsSurvival AnalysisTomography, X-Ray ComputedConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseRisk of deathStudy participantsVACS IndexPulmonary diseaseComputed tomographyImpact of COPDVeterans Aging Cohort Study (VACS) IndexMultivariable Cox regression modelsBurden of comorbiditiesPredictors of mortalityPulmonary function testingCox regression modelMedian followUninfected subjectsAirflow obstructionCohort studyPulmonary functionPulmonary variablesFunction testingMultivariable modelPLWHCT characteristicsMortality rate
2014
Findings in asymptomatic HIV-infected patients undergoing chest computed tomography testing
Sigel K, Wisnivesky J, Shahrir S, Brown ST, Justice A, Kim J, Rodriguez-Barradas MC, Akgün KM, Rimland D, Hoo GW, Crothers K. Findings in asymptomatic HIV-infected patients undergoing chest computed tomography testing. AIDS 2014, 28: 1007-1014. PMID: 24401647, PMCID: PMC4018450, DOI: 10.1097/qad.0000000000000189.Peer-Reviewed Original ResearchMeSH KeywordsAsymptomatic InfectionsCohort StudiesFemaleHIV InfectionsHumansLung NeoplasmsMaleMiddle AgedRadiography, ThoracicRisk AssessmentTomography, X-Ray ComputedConceptsNational Lung Screening TrialNLST criteriaCT findingsLung cancerCT scanHIV-Associated Lung Emphysema (EXHALE) studyAbnormal CT scansCD4 cell countChest CT findingsHigh-risk smokersAbnormal CT findingsLung cancer mortalityBalance of benefitsUninfected participantsUninfected veteransAsymptomatic HIVCD4 cellsAbnormal findingsTomography screeningUnadjusted riskHIV statusMultivariable analysisCancer mortalityChest CTClinical evaluation