2021
Impact of intensity of behavioral treatment, with or without medication treatment, for opioid use disorder on HIV outcomes in persons with HIV
Kennedy AJ, McGinnis KA, Merlin JS, Edelman EJ, Gordon AJ, Korthuis PT, Skanderson M, Williams EC, Wyse J, Oldfield B, Bryant K, Justice A, Fiellin DA, Kraemer KL. Impact of intensity of behavioral treatment, with or without medication treatment, for opioid use disorder on HIV outcomes in persons with HIV. Journal Of Substance Use And Addiction Treatment 2021, 132: 108509. PMID: 34130128, PMCID: PMC8628025, DOI: 10.1016/j.jsat.2021.108509.Peer-Reviewed Original ResearchConceptsOpioid use disorderVACS Index 2.0Viral loadMOUD receiptART initiationCD4 countART adherenceUse disordersVeterans Aging Cohort Study (VACS) dataBehavioral treatmentHIV clinical outcomesLog viral loadCD4 cell countAntiretroviral treatment initiationCohort study dataPoor health outcomesPre-post changesHIV outcomesTreatment initiationClinical outcomesMedication treatmentMOUD treatmentPWHHealth outcomesCell count
2020
Impact of behavioral and medication treatment for alcohol use disorder on changes in HIV-related outcomes among patients with HIV: A longitudinal analysis
McGinnis KA, Skanderson M, Edelman EJ, Gordon AJ, Korthuis PT, Oldfield B, Williams EC, Wyse J, Bryant K, Fiellin DA, Justice AC, Kraemer KL. Impact of behavioral and medication treatment for alcohol use disorder on changes in HIV-related outcomes among patients with HIV: A longitudinal analysis. Drug And Alcohol Dependence 2020, 217: 108272. PMID: 32971391, PMCID: PMC7757793, DOI: 10.1016/j.drugalcdep.2020.108272.Peer-Reviewed Original ResearchConceptsAlcohol use disorderDetectable VLVisits/monthUse disordersVeterans Aging Cohort Study (VACS) dataCohort study dataRace/ethnicityUndetectable VLMedian ageTreatment initiationMedication treatmentImproved adherenceHIVBehavioral treatmentFirst monthIntensity groupTreatment intensityMonthsImpact of BehavioralOutcomesLinear regression modelsLongitudinal analysisVisitsVLAdherenceInsights Provided by Depression Screening Regarding Pain, Anxiety, and Substance use in a Veteran Population
Stevens ER, Mazumdar M, Caniglia EC, Khan MR, Young KE, Edelman EJ, Gordon AJ, Fiellin DA, Maisto SA, Chichetto NE, Crystal S, Gaither JR, Justice AC, Braithwaite RS. Insights Provided by Depression Screening Regarding Pain, Anxiety, and Substance use in a Veteran Population. Journal Of Primary Care & Community Health 2020, 11: 2150132720949123. PMID: 32772883, PMCID: PMC7418233, DOI: 10.1177/2150132720949123.Peer-Reviewed Original ResearchConceptsPositive predictive valueSubstance useOdds ratioVeterans Aging Cohort Study (VACS) dataPHQ-9 scoresPrimary care settingCohort study dataTest performance characteristicsSymptoms of anxietyMedian ageDepression screeningLikelihood ratio valuesDepression screenPHQ-9Care settingsVeteran populationPredictive valueSignificant associationSymptomsDiagnostic assessmentAnxietyStudy dataAdditional informationAssociationPain
2019
Predictors of initiation of and retention on medications for alcohol use disorder among people living with and without HIV
Oldfield BJ, McGinnis KA, Edelman EJ, Williams EC, Gordon AJ, Akgün K, Crystal S, Fiellin LE, Gaither JR, Goulet JL, Korthuis PT, Marshall BDL, Justice AC, Bryant K, Fiellin DA, Kraemer KL. Predictors of initiation of and retention on medications for alcohol use disorder among people living with and without HIV. Journal Of Substance Use And Addiction Treatment 2019, 109: 14-22. PMID: 31856946, PMCID: PMC6982467, DOI: 10.1016/j.jsat.2019.11.002.Peer-Reviewed Original ResearchConceptsAlcohol use disorderUse disordersHIV statusUninfected individualsVeterans Aging Cohort Study (VACS) dataEvidence-based medicationsNew alcohol use disorderPrevalence of initiationMultivariable logistic regressionPredictors of initiationFacility-level predictorsCohort study dataMedication initiationPrescription fillsMultivariable analysisBlack raceTreatment gapDecreased oddsNew diagnosisPLWHOlder ageLogistic regressionMedicationsHIVSpecific subpopulations
2018
Gender and alcohol use
Matson TE, McGinnis KA, Rubinsky AD, Frost MC, Czarnogorski M, Bryant KJ, Edelman EJ, Satre DD, Catz SL, Bensley KM, Fiellin DA, Justice AC, Williams EC. Gender and alcohol use. AIDS 2018, 32: 2247-2253. PMID: 30005010, PMCID: PMC6136970, DOI: 10.1097/qad.0000000000001946.Peer-Reviewed Original ResearchConceptsAlcohol useHIV careViral suppressionART treatmentVeterans Aging Cohort Study (VACS) dataVeterans Health Administration patientsAUDIT-C alcoholHIV medical careHIV care continuumLarge national cohortCohort study dataPoisson regression modelsPrescribed ARTPrevalence of engagementRetrospective cohortNational cohortUS veteransWorse outcomesCare continuumRelative riskStratified analysisMedical careHIVGender modifiesWomenLevel of Alcohol Use Associated with HIV Care Continuum Targets in a National U.S. Sample of Persons Living with HIV Receiving Healthcare
Williams EC, McGinnis KA, Edelman EJ, Matson TE, Gordon AJ, Marshall BDL, Bryant KJ, Rubinsky AD, Lapham GT, Satre DD, Richards JE, Catz SL, Fiellin DA, Justice AC, Bradley KA. Level of Alcohol Use Associated with HIV Care Continuum Targets in a National U.S. Sample of Persons Living with HIV Receiving Healthcare. AIDS And Behavior 2018, 23: 140-151. PMID: 29995206, PMCID: PMC6344313, DOI: 10.1007/s10461-018-2210-6.Peer-Reviewed Original ResearchConceptsViral suppressionAlcohol use levelsART treatmentVeterans Aging Cohort Study (VACS) dataAlcohol useAUDIT-C screeningCare continuum outcomesHIV care continuumCohort study dataHigh-level drinkingPoisson regression modelsContinuum outcomesHIV treatmentAdjusted prevalenceCare engagementCare continuumGreater alcohol useHIVPatientsUse levelsTreatmentRegression modelsStudy dataNational U.S. sampleAssociationChanges in alcohol use associated with changes in HIV disease severity over time: A national longitudinal study in the Veterans Aging Cohort
Williams EC, McGinnis KA, Bobb JF, Rubinsky AD, Lapham GT, Skanderson M, Catz SL, Bensley KM, Richards JE, Bryant KJ, Edelman EJ, Satre DD, Marshall BDL, Kraemer KL, Blosnich JR, Crystal S, Gordon AJ, Fiellin DA, Justice AC, Bradley KA. Changes in alcohol use associated with changes in HIV disease severity over time: A national longitudinal study in the Veterans Aging Cohort. Drug And Alcohol Dependence 2018, 189: 21-29. PMID: 29859388, PMCID: PMC6344121, DOI: 10.1016/j.drugalcdep.2018.04.022.Peer-Reviewed Original ResearchConceptsHIV severityAUDIT-C screensViral loadAlcohol useVeterans Aging Cohort Study (VACS) dataPoor HIV controlVeterans Aging CohortHIV disease severityAUDIT-C scoresCohort study dataLow-level drinkingStable drinkingVL analysisHIV controlMean changeAging CohortDisease severityPLWHGreater riskCD4Individual alcohol useSeverityDrinking trajectoriesNational Longitudinal StudyLongitudinal study
2016
The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy
Edelman E, Gordon K, Tate J, Becker W, Bryant K, Crothers K, Gaither, Gibert C, Gordon A, Marshall B, Rodriguez‐Barradas M, Samet J, Skanderson M, Justice A, Fiellin D. The impact of prescribed opioids on CD4 cell count recovery among HIV‐infected patients newly initiating antiretroviral therapy. HIV Medicine 2016, 17: 728-739. PMID: 27186715, PMCID: PMC5053822, DOI: 10.1111/hiv.12377.Peer-Reviewed Original ResearchConceptsCD4 cell countBaseline CD4 cell countCell countPrescribed opioidsImmunosuppressive propertiesVeterans Aging Cohort Study (VACS) dataCD4 cell count recoveryAntiretroviral therapy responseCell count recoveryShort-term opioidsViral load suppressionCohort study dataOverall disease severityYear of initiationPrimary independent variableOpioid durationAntiretroviral therapyCount recoveryComorbid conditionsPharmacy dataOpioid propertiesTherapy responseOpioidsPatientsHIV