2017
Identification of HIV infection-related DNA methylation sites and advanced epigenetic aging in HIV-positive, treatment-naive U.S. veterans
Nelson KN, Hui Q, Rimland D, Xu K, Freiberg MS, Justice AC, Marconi VC, Sun YV. Identification of HIV infection-related DNA methylation sites and advanced epigenetic aging in HIV-positive, treatment-naive U.S. veterans. AIDS 2017, 31: 571-575. PMID: 27922854, PMCID: PMC5263111, DOI: 10.1097/qad.0000000000001360.Peer-Reviewed Original ResearchConceptsHIV-positive individualsHIV-negative individualsHIV infectionART initiationBlood samplesTreatment-naive HIV-positive individualsVeterans Aging Cohort StudyHIV-negative groupHIV-positive patientsAging Cohort StudyDNAm ageCohort of veteransPeripheral blood samplesNaive HIVAntiretroviral therapyAntiretroviral treatmentCohort studyStudy cohortAge-related diseasesMyocardial infarctionLarge cohortHealthy personsHigh riskHIVU.S. veterans
2009
Incidence of Non-AIDS-Defining Malignancies in HIV-Infected Versus Noninfected Patients in the HAART Era: Impact of Immunosuppression
Bedimo RJ, McGinnis KA, Dunlap M, Rodriguez-Barradas MC, Justice AC. Incidence of Non-AIDS-Defining Malignancies in HIV-Infected Versus Noninfected Patients in the HAART Era: Impact of Immunosuppression. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2009, 52: 203-208. PMID: 19617846, PMCID: PMC2814969, DOI: 10.1097/qai.0b013e3181b033ab.Peer-Reviewed Original ResearchConceptsActive antiretroviral therapy (HAART) eraAntiretroviral therapy eraIncidence rate ratiosCD4 countTherapy eraAnal cancerLow CD4 countHigher CD4 countsMedian CD4 countImpact of immunosuppressionRate ratioCohort of veteransNon-AIDSNoninfected patientsHAART eraUninfected patientsHodgkin's lymphomaIncidence rateProstate cancerHIVPatientsCancerIndividual cancersMalignancyIncidence
2006
Development and Verification of a “Virtual” Cohort Using the National VA Health Information System
Fultz SL, Skanderson M, Mole LA, Gandhi N, Bryant K, Crystal S, Justice AC. Development and Verification of a “Virtual” Cohort Using the National VA Health Information System. Medical Care 2006, 44: s25-s30. PMID: 16849965, DOI: 10.1097/01.mlr.0000223670.00890.74.Peer-Reviewed Original ResearchConceptsPositive predictive valueIntegrated electronic medical recordsOutpatient codesPredictive valueCohort of veteransVA administrative dataElectronic medical recordsAdministrative dataMajority of subjectsInpatient codesSimilar HIVHAART eraHIV infectionCase RegistryPharmacy benefit managementPharmacy dataMedical recordsClinical dataLarge cohortConfirmatory laboratoryIndependent clinical dataHIVHealth information systemsVirtual cohortCohort
2003
Testing, Referral, and Treatment Patterns for Hepatitis C Virus Coinfection in a Cohort of Veterans with Human Immunodeficiency Virus Infection
Fultz SL, Justice AC, Butt AA, Rabeneck L, Weissman S, Rodriguez-Barradas M, Team V. Testing, Referral, and Treatment Patterns for Hepatitis C Virus Coinfection in a Cohort of Veterans with Human Immunodeficiency Virus Infection. Clinical Infectious Diseases 2003, 36: 1039-1046. PMID: 12684917, DOI: 10.1086/374049.Peer-Reviewed Original ResearchConceptsAlcohol consumptionHepatitis CHuman immunodeficiency virus-positive patientsHepatitis C virus coinfectionHuman immunodeficiency virus (HIV) infectionImmunodeficiency virus-positive patientsC virus coinfectionUnderwent liver biopsyHepatitis C therapyImmunodeficiency virus infectionVirus-positive patientsHepatitis C treatmentTreatment of patientsCohort of veteransVeterans Affairs electronic medical recordsHepatitis C virusCurrent alcohol consumptionHealth care providersElectronic medical recordsC therapyCohort studyLiver biopsyTreatment patternsVirus coinfectionPsychiatric comorbidity