2021
Prostate Cancer Screening and Incidence among Aging Persons Living with HIV
Leapman MS, Stone K, Wadia R, Park LS, Gibert CL, Goetz MB, Bedimo R, Rodriguez-Barradas M, Shebl F, Justice AC, Brown ST, Crothers K, Sigel KM. Prostate Cancer Screening and Incidence among Aging Persons Living with HIV. Journal Of Urology 2021, 207: 324-332. PMID: 34555924, PMCID: PMC8741750, DOI: 10.1097/ju.0000000000002249.Peer-Reviewed Original ResearchConceptsPSA testingHIV statusProstate cancerProstate biopsyCancer incidenceHuman immunodeficiency virus statusProstate-specific antigen (PSA) testingVeterans Aging Cohort StudyProspective national cohortMultivariable Poisson modelsAging Cohort StudySpecific antigen testingHuman immunodeficiency virusProstate cancer screeningUninfected comparatorsCohort studyIncident cancerAntigen testingImmunodeficiency virusMean ageCancer screeningNational cohortCancer stageVirus statusMultivariable model
2018
Association of Viral Suppression With Lower AIDS-Defining and Non-AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study.
Park LS, Tate JP, Sigel K, Brown ST, Crothers K, Gibert C, Goetz MB, Rimland D, Rodriguez-Barradas MC, Bedimo RJ, Justice AC, Dubrow R. Association of Viral Suppression With Lower AIDS-Defining and Non-AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study. Annals Of Internal Medicine 2018, 169: 87-96. PMID: 29893768, PMCID: PMC6825799, DOI: 10.7326/m16-2094.Peer-Reviewed Original ResearchConceptsLong-term viral suppressionViral suppressionLong-term suppressionCancer incidenceCancer riskHIV treatment successLow viral suppressionViral suppression statusProspective cohort studyT-cell countsEffect of CD4HIV-positive veteransCancer incidence ratesNational InstituteNational Cancer InstituteAIDS definingNon-AIDSUninfected veteransAntiretroviral therapyExcess cancer riskProspective cohortCohort studyUninfected personsIncidence rateTreatment success
2016
Time trends in cancer incidence in persons living with HIV/AIDS in the antiretroviral therapy era
Park LS, Tate JP, Sigel K, Rimland D, Crothers K, Gibert C, Rodriguez-Barradas MC, Goetz MB, Bedimo RJ, Brown ST, Justice AC, Dubrow R. Time trends in cancer incidence in persons living with HIV/AIDS in the antiretroviral therapy era. AIDS 2016, 30: 1795-1806. PMID: 27064994, PMCID: PMC4925286, DOI: 10.1097/qad.0000000000001112.Peer-Reviewed Original ResearchConceptsAntiretroviral therapy eraIncidence rateUninfected personsTherapy eraCohort studyCancer incidenceVeterans Aging Cohort StudyImproved immune functionLarge HIV cohortProspective cohort studyCrude incidence rateIncident cancer diagnosisRisk factor prevalenceAging Cohort StudyEvidence-based screeningIncidence rate ratiosIncidence time trendsFuture cancer incidenceTime trendsHIV/AIDSTrend P valueCancer groupingsSpecific cancer typesART regimensHIV care
2015
Cumulative Incidence of Cancer Among Persons With HIV in North America: A Cohort Study.
Silverberg MJ, Lau B, Achenbach CJ, Jing Y, Althoff KN, D'Souza G, Engels EA, Hessol NA, Brooks JT, Burchell AN, Gill MJ, Goedert JJ, Hogg R, Horberg MA, Kirk GD, Kitahata MM, Korthuis PT, Mathews WC, Mayor A, Modur SP, Napravnik S, Novak RM, Patel P, Rachlis AR, Sterling TR, Willig JH, Justice AC, Moore RD, Dubrow R. Cumulative Incidence of Cancer Among Persons With HIV in North America: A Cohort Study. Annals Of Internal Medicine 2015, 163: 507-18. PMID: 26436616, PMCID: PMC4711936, DOI: 10.7326/m14-2768.Peer-Reviewed Original ResearchConceptsAge 75 yearsNon-Hodgkin lymphomaCumulative cancer incidenceCumulative incidenceLung cancerKaposi's sarcomaCalendar trendsCohort studyHIV statusHodgkin's lymphomaCancer incidenceLiver cancerNorth American AIDS Cohort CollaborationOral cavity/pharyngeal cancerHigher cumulative incidenceMortality rate trendsCohort CollaborationAnal cancerAntiretroviral therapyPharyngeal cancerSmoking cessationColorectal cancerLifetime riskIncidence trendsUninfected adults