2012
HIV as an independent risk factor for incident lung cancer
Sigel K, Wisnivesky J, Gordon K, Dubrow R, Justice A, Brown ST, Goulet J, Butt AA, Crystal S, Rimland D, Rodriguez-Barradas M, Gibert C, Park LS, Crothers K. HIV as an independent risk factor for incident lung cancer. AIDS 2012, 26: 1017-1025. PMID: 22382152, PMCID: PMC3580210, DOI: 10.1097/qad.0b013e328352d1ad.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosIndependent risk factorUninfected patientsLung cancerSimilar HIVHIV infectionSurveillance biasRisk factorsIncidence rateVeterans Aging Cohort Study Virtual CohortVeterans Affairs Central Cancer RegistryChronic obstructive pulmonary diseaseIncident lung cancerObstructive pulmonary diseaseCentral Cancer RegistryLung cancer stageSimilar stage distributionRace/ethnicityExcess smokingMultivariable adjustmentAnalytic cohortPulmonary diseaseBacterial pneumoniaCancer RegistryPotential confounders
2010
HIV Infection and Risk for Incident Pulmonary Diseases in the Combination Antiretroviral Therapy Era
Crothers K, Huang L, Goulet JL, Goetz MB, Brown ST, Rodriguez-Barradas MC, Oursler KK, Rimland D, Gibert CL, Butt AA, Justice AC. HIV Infection and Risk for Incident Pulmonary Diseases in the Combination Antiretroviral Therapy Era. American Journal Of Respiratory And Critical Care Medicine 2010, 183: 388-395. PMID: 20851926, PMCID: PMC3266024, DOI: 10.1164/rccm.201006-0836oc.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseObstructive pulmonary diseaseCombination antiretroviral therapy eraAntiretroviral therapy eraPulmonary diseaseTherapy eraPulmonary infectionHIV infectionVeterans Aging Cohort Study Virtual CohortIncident chronic obstructive pulmonary diseaseLower HIV RNA levelsVirtual cohortVeterans Affairs Healthcare SystemAssociation of HIVMost pulmonary diseasesHIV RNA levelsRates of asthmaIncidence rate ratiosSelf-reported smokingLarge Health SurveyPulmonary hypertensionUninfected patientsComorbid diseasesOpportunistic pneumoniaBacterial pneumonia
2006
Medical Disease and Alcohol Use Among Veterans With Human Immunodeficiency Infection
Justice AC, Lasky E, McGinnis KA, Skanderson M, Conigliaro J, Fultz SL, Crothers K, Rabeneck L, Rodriguez-Barradas M, Weissman SB, Bryant K. Medical Disease and Alcohol Use Among Veterans With Human Immunodeficiency Infection. Medical Care 2006, 44: s52-s60. PMID: 16849969, DOI: 10.1097/01.mlr.0000228003.08925.8c.Peer-Reviewed Original ResearchConceptsICD-9 diagnostic codesICD-9 codesChart reviewMedical diseasesDiagnostic codesAlcohol useHepatitis CLevel of exposureHIV infectionAlcohol exposureMultivariate modelGreater exposure levelsCD4 cell countHIV-positive patientsIntravenous drug useObstructive lung diseaseHuman immunodeficiency infectionCurrent alcohol useNonlinearity of associationsDiagnosis of abuseCohort studyBacterial pneumoniaPast drinkersViral loadLung disease
2005
The Impact of Cigarette Smoking on Mortality, Quality of Life, and Comorbid Illness Among HIV‐Positive Veterans
Crothers K, Griffith TA, McGinnis KA, Rodriguez‐Barradas M, Leaf DA, Weissman S, Gibert CL, Butt AA, Justice AC. The Impact of Cigarette Smoking on Mortality, Quality of Life, and Comorbid Illness Among HIV‐Positive Veterans. Journal Of General Internal Medicine 2005, 20: 1142-1145. PMID: 16423106, PMCID: PMC1490270, DOI: 10.1111/j.1525-1497.2005.0255.x.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseQuality of lifeHIV-positive patientsImpact of smokingPhysical component summaryHIV-positive veteransCurrent smokersRespiratory symptomsBacterial pneumoniaActive antiretroviral therapyCD4 cell countHIV RNA levelsProspective observational studyObstructive pulmonary diseaseShort Form-12National VA databasesRace/ethnicityAntiretroviral therapyComorbid illnessesComponent summaryHIV infectionPatient questionnairePulmonary diseaseChart extractionCigarette smoking