Estrogen enhances stress-induced prefrontal cortex dysfunction: relevance to Major Depressive Disorder in women
Shansky R, Arnsten A. Estrogen enhances stress-induced prefrontal cortex dysfunction: relevance to Major Depressive Disorder in women. Dialogues In Clinical Neuroscience 2006, 8: 478-481. PMCID: PMC3181833.Peer-Reviewed Original ResearchMajor depressive disorderPost-traumatic stress disorderDepressive disorderPrevalence of MDDPrefrontal cortex dysfunctionMost anxiety disordersAnimal modelsMental illnessBrain regionsEstrogenStress disorderAnxiety disordersNeurobiological responsesWomenDisordersEffects of stressLiterature demonstratingMenGreater vulnerabilityBiological causesDysfunctionIllnessPrevalenceStress responseBrain