2017
The aged rhesus macaque manifests Braak stage III/IV Alzheimer's‐like pathology
Paspalas CD, Carlyle BC, Leslie S, Preuss TM, Crimins JL, Huttner AJ, van Dyck C, Rosene DL, Nairn AC, Arnsten AFT. The aged rhesus macaque manifests Braak stage III/IV Alzheimer's‐like pathology. Alzheimer's & Dementia 2017, 14: 680-691. PMID: 29241829, PMCID: PMC6178089, DOI: 10.1016/j.jalz.2017.11.005.Peer-Reviewed Original ResearchConceptsLate-onset Alzheimer's diseaseCortical pathologyEntorhinal cortexAnimal modelsBraak stage III/IVAlzheimer's diseaseStage III/IVRhesus macaquesProgression of tauAlzheimer-like pathologyPrimary visual cortexSequence of tauDorsolateral prefrontal cortexTau pathologyPreventive strategiesAssociation cortexVisual cortexPrefrontal cortexCortexPathologyDiseaseOld animalsProtein kinase A (PKA) phosphorylationGenetic insultsMacaques
2015
Stress weakens prefrontal networks: molecular insults to higher cognition
Arnsten AF. Stress weakens prefrontal networks: molecular insults to higher cognition. Nature Neuroscience 2015, 18: 1376-1385. PMID: 26404712, PMCID: PMC4816215, DOI: 10.1038/nn.4087.Peer-Reviewed Original Research
2012
Attention deficit hyperactivity disorder
Berridge C, Devilbiss D, Spencer R, Schmeichel B, Arnsten A. Attention deficit hyperactivity disorder. 2012, 303-320. DOI: 10.1017/cbo9780511980053.018.Peer-Reviewed Original ResearchAttention deficit hyperactivity disorderDeficit hyperactivity disorderHyperactivity disorderNeurodevelopmental disordersMore effective treatmentsMultiple sclerosisDisease groupEffective treatmentParkinson's diseaseBipolar disorderBrain disordersAlzheimer's diseaseClinical advancementTranslational neuroscienceSubstance abuseDiseaseDisordersField of psychiatryPublic healthCliniciansNeurologyPsychiatryPainSclerosisEpilepsy
2007
Norepinephrine and cognitive disorders
Arnsten A. Norepinephrine and cognitive disorders. 2007, 408-435. DOI: 10.1017/cbo9780511544156.015.Peer-Reviewed Original ResearchNoradrenergic drugsCentral nervous system norepinephrineNervous system norepinephrineRole of norepinephrineNoradrenergic neuronsCNS diseaseTherapeutic effectCognitive disordersNorepinephrineNeurological disordersNorepinephrine's roleBrain diseasesNew disease indicationsChemical neurotransmittersDisease indicationsDrugsDiseasePharmacologyDisordersTherapeuticsBasic biologyMolecular biologyNeurotransmittersNeuronsBrain