2023
Ovarian absence: a systematic literature review and case series report
Chen H, Grimshaw A, Taylor-Giorlando M, Vijayakumar P, Li D, Margetts M, Pelosi E, Vash-Margita A. Ovarian absence: a systematic literature review and case series report. Journal Of Ovarian Research 2023, 16: 13. PMID: 36642704, PMCID: PMC9841619, DOI: 10.1186/s13048-022-01090-1.Peer-Reviewed Original ResearchConceptsOvarian absenceUterine abnormalitiesVascular accidentRenal abnormalitiesInfertility/subfertilityCase series reportWeb of SciencePelvic painDiagnostic laparoscopyClinical presentationVascular etiologyOvid EmbaseCochrane LibraryFrequent presentationUncommon conditionSeries reportCongenital anomaliesOvid MEDLINEOvarian abnormalitiesFertility considerationsGenitourinary anatomyExclusion criteriaEmbryological defectUnpublished casesSystematic review
2021
The Embryological Landscape of Mayer-Rokitansky-Kuster-Hauser Syndrome: Genetics and Environmental Factors.
Kyei-Barffour I, Margetts M, Vash-Margita A, Pelosi E. The Embryological Landscape of Mayer-Rokitansky-Kuster-Hauser Syndrome: Genetics and Environmental Factors. The Yale Journal Of Biology And Medicine 2021, 94: 657-672. PMID: 34970104, PMCID: PMC8686787.Peer-Reviewed Original ResearchConceptsMRKH syndromeClinical presentationMayer-RokitanskyEmbryonic developmentEnvironmental factorsEpigenetic changesFunctional validationCandidate genesGenetic analysisMolecular mechanismsDevelopmental pathwaysKüster-Hauser syndromeEarly organogenesisKuster-Hauser syndromeKey pathwaysGenetic componentInheritance patternEnvironmental compoundsIncomplete penetranceClinical managementDiscordant phenotypesEarly diagnosisAnimal modelsGeneticsTranslational studiesProgression of Cystadenoma to Mucinous Borderline Ovarian Tumor in Young Females: Case Series and Literature Review
Beroukhim G, Ozgediz D, Cohen PJ, Hui P, Morotti R, Schwartz PE, Yang-Hartwich, Vash-Margita A. Progression of Cystadenoma to Mucinous Borderline Ovarian Tumor in Young Females: Case Series and Literature Review. Journal Of Pediatric And Adolescent Gynecology 2021, 35: 359-367. PMID: 34843973, DOI: 10.1016/j.jpag.2021.11.003.Peer-Reviewed Original ResearchConceptsMucinous borderline ovarian tumorsBorderline ovarian tumorsOvarian tumorsYale-New Haven HospitalRetrospective chart reviewBenign ovarian tumorsBenign ovarian lesionsRate of recurrenceNew Haven HospitalAbdominal painPreoperative characteristicsChart reviewDisease recurrenceRecurrent cystsCase seriesChief complaintClinical presentationClinicopathologic featuresFemale patientsMucinous cystadenomaOvarian cystsOvarian lesionsTumor stageAdolescent patientsSubsequent surveillance3. SWIFT Accurately Predicts Lichen Sclerosus among Premenarchal Girls
Wang M, Wininger M, Vash-Margita A. 3. SWIFT Accurately Predicts Lichen Sclerosus among Premenarchal Girls. Journal Of Pediatric And Adolescent Gynecology 2021, 34: 240-241. DOI: 10.1016/j.jpag.2021.02.007.Peer-Reviewed Original ResearchLichen sclerosusPremenarchal girlsUrinary incontinenceVulvar complaintsPhysical examRetrospective chart reviewRisk stratification toolAdolescent gynecology clinicInstitutional review boardPremenarchal patientsChart reviewGynecology clinicClinical presentationTertiary hospitalVulvar irritationUnique patientsBackground prevalenceLS diagnosisVulvar biopsyPatient visitsInclusion criteriaEffective treatmentAverage ageDichotomous outcomesPatients
2020
Characteristics Among Premenarchal Girls With Lichen Sclerosus.
Wang M, Arlen AM, Vash-Margita A. Characteristics Among Premenarchal Girls With Lichen Sclerosus. Journal Of Lower Genital Tract Disease 2020, 25: 152-157. PMID: 33284147, DOI: 10.1097/lgt.0000000000000584.Peer-Reviewed Original ResearchConceptsLower urinary tract symptomsResolution/improvementPremenarchal girlsRetrospective chart reviewUrinary tract symptomsChronic inflammatory dermatosisPediatric urology clinicPediatric–adolescent gynecologyPaucity of dataL symptomsLS symptomsLUTS symptomsVulvar LSBowel symptomsPostmenopausal womenTract symptomsVoiding symptomsChart reviewMedian ageLichen sclerosusClinical presentationUrology clinicInflammatory dermatosesLS diagnosisPrepubertal girls