Featured Publications
Epilepsy Surgery: A Practical Case-Based Approach 2024th Edition
Published by Springer International Publishing, May 2023 DOI 10.1007/978-3-031-23828-4 ISBNs 978-3-03-123827-7, 978-3-03-123828-4Books
2024
Combined neuromodulation and resection for functional cortex epilepsy: a case series.
Merenzon M, Sivaraju A, Herlopian A, Gerrard J, Quraishi I, Hirsch L, Spencer D, Damisah E. Combined neuromodulation and resection for functional cortex epilepsy: a case series. Journal Of Neurosurgery 2024, 1-9. PMID: 38848588, DOI: 10.3171/2024.3.jns24122.Peer-Reviewed Original ResearchMedically refractory epilepsySeizure onset zoneFunctional cortexSeizure outcomeRefractory epilepsyMonths of follow-up dataMaximal safe resectionMedian follow-upTreated with resectionImprove seizure outcomeFocal neuromodulationFollow-up dataPreservation of functionRetrospective analysis of individualsSafe resectionPartial resectionMedian intervalCase seriesPreoperative assessmentSurgical interventionRNS deviceNeurological deficitsNo significant changesResectionRetrospective analysisImproving Clinician Performance in Classifying EEG Patterns on the Ictal-Interictal Injury Continuum Using Interpretable Machine Learning.
Barnett A, Guo Z, Jing J, Ge W, Kaplan P, Kong W, Karakis I, Herlopian A, Jayagopal L, Taraschenko O, Selioutski O, Osman G, Goldenholz D, Rudin C, Westover M. Improving Clinician Performance in Classifying EEG Patterns on the Ictal-Interictal Injury Continuum Using Interpretable Machine Learning. NEJM AI 2024, 1 PMID: 38872809, PMCID: PMC11175595, DOI: 10.1056/aioa2300331.Peer-Reviewed Original ResearchDominant, Mesial Temporal Lobe Epilepsy Due to Hippocampal Sclerosis
Herlopian A. Dominant, Mesial Temporal Lobe Epilepsy Due to Hippocampal Sclerosis. 2024, 735-745. DOI: 10.1007/978-3-031-23828-4_29.Peer-Reviewed Original ResearchHippocampal sclerosisOlfactory hallucinationsNeuropsychological outcomesTemporal lobe epilepsyMesial temporal lobe epilepsyDeep brain stimulationHippocampalVisual field defectsBrain stimulationLobe epilepsyThermoablative therapyField defectsSeizure outcomePost-ablationFebrile seizuresPharmacoresistant epilepsyPotential complicationsTherapyPatientsPalilaliaSclerosisHallucinationsHippocampusEpilepsySniffingNon-dominant, Non-lesional Mesial Temporal Lobe Epilepsy
Herlopian A, Mattson R. Non-dominant, Non-lesional Mesial Temporal Lobe Epilepsy. 2024, 63-86. DOI: 10.1007/978-3-031-23828-4_4.Peer-Reviewed Original ResearchTemporal lobe epilepsyLobe epilepsySurgical outcomesMRI-negative temporal lobe epilepsyInterictal PET scanPharmacoresistant temporal lobe epilepsyPost-operative resultsFavorable post-operative resultsTemporal lobe seizuresSlow wave activityMRI-negativePET scansHypermotor symptomsPharmacoresistant epilepsyRespiratory manifestationsNon-lesionalFronto-parietal cortexPatientsEpilepsyImpaired awarenessNon-dominant, Lesional Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Temporal Lobe Epilepsy. 2024, 361-374. DOI: 10.1007/978-3-031-23828-4_16.Peer-Reviewed Original ResearchDominant, Non-lesional Frontal and Parietal Lobe Epilepsy
Herlopian A. Dominant, Non-lesional Frontal and Parietal Lobe Epilepsy. 2024, 669-697. DOI: 10.1007/978-3-031-23828-4_27.Peer-Reviewed Original ResearchNon-lesional Bilateral Mesial Temporal Lobe Epilpesy
Quraishi I, Herlopian A. Non-lesional Bilateral Mesial Temporal Lobe Epilpesy. 2024, 781-818. DOI: 10.1007/978-3-031-23828-4_32.ChaptersMultifocal Epilepsy Due to New-Onset Refractory Status Epilepticus
Herlopian A, Gunawardane N. Multifocal Epilepsy Due to New-Onset Refractory Status Epilepticus. 2024, 497-532. DOI: 10.1007/978-3-031-23828-4_21.Peer-Reviewed Original ResearchRefractory status epilepticusStatus epilepticusNew-onset refractory status epilepticusOnset refractory status epilepticusSuper-refractory status epilepticusSingle pulse electrical stimulationCortico-cortical evoked potentialsResponsive neurostimulation deviceNew-onsetMultifocal epilepsySurgical interventionNeuroimaging characteristicsEpilepticusPulse electrical stimulationEpileptic networkEvaluate functional connectivityPatientsCortical stimulationNeurostimulation devicesElectrical stimulationFunctional connectivityLanguage mappingStimulationNon-dominant, Lesional Hemispheric Epilepsy
Herlopian A. Non-dominant, Lesional Hemispheric Epilepsy. 2024, 653-666. DOI: 10.1007/978-3-031-23828-4_26.Peer-Reviewed Original ResearchNon-dominant, Temporal Lobe Epilepsy Due to Dual Pathology
Herlopian A. Non-dominant, Temporal Lobe Epilepsy Due to Dual Pathology. 2024, 175-187. DOI: 10.1007/978-3-031-23828-4_9.Peer-Reviewed Original ResearchNon-dominant, Lesional Frontal Lobe Epilepsy Involving the Prefrontal Cortex
Herlopian A. Non-dominant, Lesional Frontal Lobe Epilepsy Involving the Prefrontal Cortex. 2024, 189-220. DOI: 10.1007/978-3-031-23828-4_10.Peer-Reviewed Original ResearchDominant, Lesional Posterior Quadrant Epilepsy
Herlopian A, Tolba H, Mattson R. Dominant, Lesional Posterior Quadrant Epilepsy. 2024, 757-777. DOI: 10.1007/978-3-031-23828-4_31.Peer-Reviewed Original ResearchIctal high-frequency oscillationsPeriventricular nodular heterotopiaPredicting surgical outcomesSurgical decision-making processFocal cortical dysplasiaPropagation of seizuresInterictal epileptiform dischargesThermoablative therapyNodular heterotopiaSurgical outcomesCortical dysplasiaIctal patternsCortical malformationsEpileptiform dischargesIntracranial monitoringPharmacoresistant epilepsyClonic movementsIctal vocalizationSpeech disturbanceCephalic auraTherapyPatientsHigh-frequency oscillationsAcquired, Lesional Lennox-Gastaut Syndrome
Herlopian A. Acquired, Lesional Lennox-Gastaut Syndrome. 2024, 919-943. DOI: 10.1007/978-3-031-23828-4_37.Peer-Reviewed Original ResearchCentromedian nucleusConfirm electrode placementGeneralized atonic seizuresLennox-Gastaut syndromeCentromedian thalamic nucleusLanguage lateralizationPost-operative language deficitsRare entityLennox-GastautCorpus callosotomySurgical interventionCortical malformationsAtonic seizuresSurgical proceduresThalamic nucleiCorpus callosumEpileptic networkDeep brain stimulation devicesLanguage deficitsNeurostimulation devicesElectrode placementPatientsNeurophysiological recordingsEpilepsyLanguageNon-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex
Herlopian A. Non-dominant, Lesional Frontal Lobe Epilepsy Overlapping with Motor Cortex. 2024, 469-496. DOI: 10.1007/978-3-031-23828-4_20.Peer-Reviewed Original ResearchFocal cortical dysplasiaCortical dysplasiaIntracranial monitoringPredictors of seizure freedomIctal onset patternsPost-operative outcomesSurgical decision-making processFrontal lobe epilepsySensorimotor functionDysplastic cortexResection marginsSurgical interventionSeizure freedomEpileptiform patternsLobe epilepsyPharmacoresistant epilepsyMotor cortexOnset patternsDysplasiaCortexPatientsCircuit organizationEpileptiformEpilepsyDominant, Lesional Congenital Hemispheric Epilepsy
Herlopian A, Mahmud S, Mattson R. Dominant, Lesional Congenital Hemispheric Epilepsy. 2024, 699-731. DOI: 10.1007/978-3-031-23828-4_28.Peer-Reviewed Original ResearchCorpus callosotomyPorencephalic cystPartial frontal lobe resectionGeneralized atonic seizuresAnterior corpus callosotomyFrontal lobe resectionStartle-induced seizuresThalamic hypometabolismAtonic seizuresLobe resectionNeuroimaging findingsHemispheric epilepsyCallosotomyPatientsComplex symptomsSeizuresCystsEpilepsyNon-dominant, Lesional Neocortical Temporal Lobe Epilepsy
Herlopian A. Non-dominant, Lesional Neocortical Temporal Lobe Epilepsy. 2024, 105-134. DOI: 10.1007/978-3-031-23828-4_6.Peer-Reviewed Original ResearchVacuolating neuronal tumorInterictal high-frequency oscillationsDysembryoplastic neuroepithelial tumorEpileptic networkSurgical decision-making processFocal cortical dysplasiaNeuroepithelial tumorsNeuronal tumorsRadiological findingsCortical dysplasiaClinical manifestationsIctal semiologyPharmacoresistant epilepsyDystonic posturingTumorHigh-frequency oscillationsMultifocal Epilepsy and Non-dominant Cingulate Lesion
Herlopian A, Gray T, Quraishi I. Multifocal Epilepsy and Non-dominant Cingulate Lesion. 2024, 393-429. DOI: 10.1007/978-3-031-23828-4_18.ChaptersMultifocal epilepsyEEG findings of patientsFindings of patientsAnti-seizure medicationsPrognostic roleSurgical outcomesEEG findingsEEG changesCingulate epilepsyHabitual seizuresIctal tachycardiaAnterior cingulate gyrusEpilepsy monitoring unitVascular lesionsIctal speechPredictive valueOutcome determinantsPatientsMonitor unitsCingulate cortexEpilepsyCingulate gyrusCingulateCortexEEGNon-dominant, Non-lesional Orbitofrontal-Plus Epilepsy
Herlopian A. Non-dominant, Non-lesional Orbitofrontal-Plus Epilepsy. 2024, 563-598. DOI: 10.1007/978-3-031-23828-4_23.Peer-Reviewed Original ResearchResection surgeryIntracranial monitoringInterictal PET scanIctal onset patternsPost-operative outcomesNon-lesional epilepsySurgical work-upInterictal epileptiform dischargesNon-invasive modalityDelta slowingEEG findingsInvestigative armamentariumTonic seizuresEpileptiform dischargesPET scansIctal propagationWidespread hypometabolismWork-upInsular epilepsyPsychiatric manifestationsOnset patternsSpike rateEpilepsySurgeryPatientsHypothalamic Hamartoma
Herlopian A. Hypothalamic Hamartoma. 2024, 327-338. DOI: 10.1007/978-3-031-23828-4_14.Peer-Reviewed Original Research