2023
Cerebral embolic protection during transcatheter heart interventions.
Jimenez Diaz V, Kapadia S, Linke A, Mylotte D, Lansky A, Grube E, Settergren M, Puri R. Cerebral embolic protection during transcatheter heart interventions. EuroIntervention 2023, 19: 549-570. PMID: 37720969, PMCID: PMC10495748, DOI: 10.4244/eij-d-23-00166.Peer-Reviewed Original ResearchConceptsCerebral embolic protection devicesTranscatheter aortic valve replacementNew cerebral lesionsMajority of patientsCerebral lesionsTransfemoral transcatheter aortic valve replacementHeart interventionsCerebral embolic protectionAortic valve replacementEmbolic protection devicesBrain imaging studiesPrimary endpointDevastating complicationPeriprocedural strokeValve replacementEmbolic protectionEmbolic showerApparent strokeCerebral embolisationTranscatheter proceduresSpecific trialsImaging studiesStrokePatientsLesionsEffects of Elective Coronary Revascularization vs Medical Therapy Alone on Noncardiac Mortality A Meta-Analysis
Navarese E, Lansky A, Farkouh M, Grzelakowska K, Bonaca M, Gorog D, Raggi P, Kelm M, Yeo B, Umińska J, Curzen N, Kubica J, Wijns W, Kereiakes D. Effects of Elective Coronary Revascularization vs Medical Therapy Alone on Noncardiac Mortality A Meta-Analysis. JACC Cardiovascular Interventions 2023, 16: 1144-1156. PMID: 37225285, DOI: 10.1016/j.jcin.2023.02.030.Peer-Reviewed Original ResearchConceptsChronic coronary syndromeElective coronary revascularizationNoncardiac mortalityMedical therapyCoronary revascularizationTrial sequential analysisCumulative Z-curveRate ratioA Meta-AnalysisRandom-effects modelMeta-analysis findingsCoronary syndromeISCHEMIA trialRandomized trialsTrial evidenceRevascularizationTreatment groupsPrespecified endpointsMeta-AnalysisPatientsMortalityFutility boundariesDeath rateTrialsTreatment effects
2013
The collateral circulation of the heart
Meier P, Schirmer SH, Lansky AJ, Timmis A, Pitt B, Seiler C. The collateral circulation of the heart. BMC Medicine 2013, 11: 143. PMID: 23735225, PMCID: PMC3689049, DOI: 10.1186/1741-7015-11-143.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseCollateral arteriesArtery diseaseCollateral circulationCoronary arteryOcclusive coronary artery diseaseRelevant protective roleEpicardial coronary arteriesFirst clinical trialIntracoronary pressure measurementsRecent pilot studyExternal counterpulsationEnd arteriesClinical trialsBlood supplyArteryProtective roleGranulocyte colonyAnastomotic vesselsPilot studyGrowth factorGold standardDiseasePressure measurementsVessels
2002
Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction
Stone GW, Peterson MA, Lansky AJ, Dangas G, Mehran R, Leon MB. Impact of normalized myocardial perfusion after successful angioplasty in acute myocardial infarction. Journal Of The American College Of Cardiology 2002, 39: 591-597. PMID: 11849856, DOI: 10.1016/s0735-1097(01)01779-x.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionTIMI 3 flowAcute myocardial infarctionMyocardial infarctionMyocardial perfusionMyocardial blushSuccessful angioplastyAngiographic myocardial blush gradeOne-year cumulative mortalityEpicardial coronary flowMyocardial blush scoreNormal myocardial blushHigh-risk featuresHigh-risk patientsMyocardial blush gradeAbnormal myocardial perfusionMyocardial perfusion gradePercutaneous coronary interventionSurvival of patientsNormal myocardial perfusionTIMI 0Blush gradeCardiogenic shockInfarct arteryCoronary intervention