2010
Selection Criteria for Drug-Eluting Versus Bare-Metal Stents and the Impact of Routine Angiographic Follow-Up 2-Year Insights From the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial
Stone GW, Parise H, Witzenbichler B, Kirtane A, Guagliumi G, Peruga JZ, Brodie BR, Dudek D, Möckel M, Lansky AJ, Mehran R. Selection Criteria for Drug-Eluting Versus Bare-Metal Stents and the Impact of Routine Angiographic Follow-Up 2-Year Insights From the HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial. Journal Of The American College Of Cardiology 2010, 56: 1597-1604. PMID: 20888162, DOI: 10.1016/j.jacc.2010.08.608.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPaclitaxel-eluting stentsBare metal stentsDrug-eluting stentsElevation myocardial infarctionRisk factorsMyocardial infarctionClinical benefitVersus Bare-Metal StentsAbsolute incremental benefitHORIZONS-AMI trialBaseline risk factorsReference vessel diameterAngiographic Follow-upAbsolute treatment effectLesion revascularizationTLR proceduresTLR rateDiabetes mellitusIndependent predictorsRisk strataFollow-upRisk groupsHigh riskAntirestenotic properties
2008
Angiographic Surrogate End Points in Drug-Eluting Stent Trials A Systematic Evaluation Based on Individual Patient Data From 11 Randomized, Controlled Trials
Pocock SJ, Lansky AJ, Mehran R, Popma JJ, Fahy MP, Na Y, Dangas G, Moses JW, Pucelikova T, Kandzari DE, Ellis SG, Leon MB, Stone GW. Angiographic Surrogate End Points in Drug-Eluting Stent Trials A Systematic Evaluation Based on Individual Patient Data From 11 Randomized, Controlled Trials. Journal Of The American College Of Cardiology 2008, 51: 23-32. PMID: 18174032, DOI: 10.1016/j.jacc.2007.07.084.Peer-Reviewed Original ResearchConceptsDrug-eluting stentsBare metal stentsAngiographic measuresTLR riskEnd pointDifferent drug-eluting stentsPrimary end pointRisk of TLRFollow-up angiographyLower revascularization ratesSurrogate end pointsIndividual patient dataSuitable surrogate markerDES trialsRevascularization ratesTLR rateClinical restenosisControlled TrialsFuture trialsStent implantationStent trialsSurrogate marker
2006
Drug-Eluting and Bare Nitinol Stents for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: Long-Term Results from the SIROCCO Trial
Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Oliva V, Tielbeek A, Anderson J, Wiesinger B, Tepe G, Lansky A, Jaff MR, Mudde C, Tielemans H, Beregi JP. Drug-Eluting and Bare Nitinol Stents for the Treatment of Atherosclerotic Lesions in the Superficial Femoral Artery: Long-Term Results from the SIROCCO Trial. Journal Of Endovascular Therapy 2006, 13: 701-710. PMID: 17154704, DOI: 10.1583/05-1704.1.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlloysAngioplasty, BalloonAnti-Bacterial AgentsAtherosclerosisBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleDouble-Blind MethodDrug CarriersFemaleFemoral ArteryHumansKaplan-Meier EstimateMaleMiddle AgedProspective StudiesProsthesis FailureRecurrenceSafetySirolimusStentsTreatment OutcomeConceptsChronic limb ischemiaAnkle-brachial indexBare stent groupRestenosis rateSirolimus groupLimb ischemiaStent groupSuperficial femoral artery occlusionType C lesionsDouble-blinded studySymptoms of claudicationBare nitinol stentsMajority of patientsSuperficial femoral arteryFemoral artery occlusionStent restenosis rateNitinol self-expanding stentsSelf-expanding stentsTypes of stentsTVR ratesTLR rateArtery occlusionC lesionsClinical outcomesDrug-Eluting
2003
Optimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries
Iakovou I, Mintz GS, Dangas G, Abizaid A, Mehran R, Lansky AJ, Kobayashi Y, Hirose M, Ashby DT, Stone GW, Moses JW, Leon MB. Optimal final lumen area and predictors of target lesion revascularization after stent implantation in small coronary arteries. The American Journal Of Cardiology 2003, 92: 1171-1176. PMID: 14609591, DOI: 10.1016/j.amjcard.2003.07.025.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationGreater stent expansionSmall coronary arteriesCoronary arteryLesion revascularizationTLR rateStent implantationStent areaSmall vesselsPredictors of TLRAngiographic reference vessel diameterGroup IStent expansionLumen areaHigher TLR rateGroup II patientsBaseline patient characteristicsReference vessel diameterPrior myocardial infarctionEarly clinical eventsReference vessel areaFinal lumen areaHospital outcomesClinical restenosisPatient characteristics
2000
Randomized Comparison of GR-II Stent and Palmaz-Schatz Stent for Elective Treatment of Coronary Stenoses
Lansky A, Roubin G, O’Shaughnessy C, Moore P, Dean L, Raizner A, Safian R, Zidar J, Kerr J, Popma J, Mehran R, Kuntz R, Leon M. Randomized Comparison of GR-II Stent and Palmaz-Schatz Stent for Elective Treatment of Coronary Stenoses. Circulation 2000, 102: 1364-1368. PMID: 10993853, DOI: 10.1161/01.cir.102.12.1364.Peer-Reviewed Original ResearchConceptsCoronary stenosisPalmaz-SchatzElective treatmentDe novo native coronary stenosisStent minimal lumen diameterMultivariate logistic regression analysisPrimary end pointTarget lesion revascularizationFree survival rateStent thrombosis ratesLong-term followNative coronary stenosisMinimal lumen diameterLogistic regression analysisPalmaz-Schatz stentsBalloon angioplasty proceduresRestenosis frequencyAngiographic restenosisLesion revascularizationProspective multicenterTLR rateFree survivalAcute treatmentConsecutive patientsDiabetes mellitusPercutaneous revascularization of the internal mammary artery graft: short- and long-term outcomes
Gruberg L, Dangas G, Mehran R, Hong M, Waksman R, Mintz G, Kent K, Pichard A, Satler L, Lansky A, Stone G, Leon M. Percutaneous revascularization of the internal mammary artery graft: short- and long-term outcomes. Journal Of The American College Of Cardiology 2000, 35: 944-948. PMID: 10732892, DOI: 10.1016/s0735-1097(99)00652-x.Peer-Reviewed Original ResearchConceptsInternal mammary artery graftMammary artery graftsIMA graftsPercutaneous revascularizationBalloon angioplastyArtery graftClinical outcomesProcedural successMyocardial infarctionOne-year clinical outcomesLong-term clinical outcomesQ-wave myocardial infarctionAlternative interventional techniquesLower TLR rateUrgent bypass surgeryHigh procedural successLong-term outcomesTreatment of stenosisLong-term resultsOne-year ratesHospital complicationsHospital outcomesTLR rateAnastomotic lesionsBypass surgery