2012
First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial.
Qian J, Xu B, Lansky AJ, Yang YJ, Qiao SB, Wu YJ, Chen J, Hu FH, Yang WX, Mintz GS, Leon MB, Gao RL. First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial. Chinese Medical Journal 2012, 125: 970-6. PMID: 22613516.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsQuantitative coronary angiographyDrug-eluting stentsAbluminal grooveMyocardial infarctionDe novo coronary artery diseaseDe novo native coronary stenosisIschemia-driven target lesion revascularizationNovo coronary artery diseaseStent late lumen lossFirst-generation drug-eluting stentsComplete strut coverageAdverse cardiac eventsTarget lesion revascularizationTarget vessel revascularizationClinical success rateCoronary artery diseaseLate lumen lossNative coronary stenosisPrior myocardial infarctionStent late lossLate DES thrombosisLong-term restenosisLesion revascularizationPrimary endpoint
2000
Randomized Comparison of GR-II Stent and Palmaz-Schatz Stent for Elective Treatment of Coronary Stenoses
Lansky A, Roubin G, O’Shaughnessy C, Moore P, Dean L, Raizner A, Safian R, Zidar J, Kerr J, Popma J, Mehran R, Kuntz R, Leon M. Randomized Comparison of GR-II Stent and Palmaz-Schatz Stent for Elective Treatment of Coronary Stenoses. Circulation 2000, 102: 1364-1368. PMID: 10993853, DOI: 10.1161/01.cir.102.12.1364.Peer-Reviewed Original ResearchConceptsCoronary stenosisPalmaz-SchatzElective treatmentDe novo native coronary stenosisStent minimal lumen diameterMultivariate logistic regression analysisPrimary end pointTarget lesion revascularizationFree survival rateStent thrombosis ratesLong-term followNative coronary stenosisMinimal lumen diameterLogistic regression analysisPalmaz-Schatz stentsBalloon angioplasty proceduresRestenosis frequencyAngiographic restenosisLesion revascularizationProspective multicenterTLR rateFree survivalAcute treatmentConsecutive patientsDiabetes mellitus
1998
Paradoxic Decreases in Atherosclerotic Plaque Mass in Insulin-Treated Diabetic Patients
Kornowski R, Mintz G, Lansky A, Hong M, Kent K, Pichard A, Satler L, Popma J, Bucher T, Leon M. Paradoxic Decreases in Atherosclerotic Plaque Mass in Insulin-Treated Diabetic Patients. The American Journal Of Cardiology 1998, 81: 1298-1304. PMID: 9631966, DOI: 10.1016/s0002-9149(98)00157-x.Peer-Reviewed Original ResearchConceptsArterial areaPlaque accumulationLumen compromiseDe novo native coronary stenosisInsulin-treated patientsInsulin-treated diabeticsNative coronary stenosisMultivariate linear regression analysisAtherosclerotic lesion formationBody surface areaParadoxic decreaseInsulin useDiabetes mellitusDiabetic patientsIndependent predictorsRemodeling indexAnginal syndromePlaque burdenCoronary stenosisArterial shrinkageInsulin treatmentPlaque massIntravascular ultrasoundLinear regression analysisReference segments