2014
Local versus general anesthesia for transcatheter aortic valve implantation (TAVR) – systematic review and meta-analysis
Fröhlich GM, Lansky AJ, Webb J, Roffi M, Toggweiler S, Reinthaler M, Wang D, Hutchinson N, Wendler O, Hildick-Smith D, Meier P. Local versus general anesthesia for transcatheter aortic valve implantation (TAVR) – systematic review and meta-analysis. BMC Medicine 2014, 12: 41. PMID: 24612945, PMCID: PMC4022332, DOI: 10.1186/1741-7015-12-41.Peer-Reviewed Original ResearchConceptsShorter hospital stayGeneral anesthesiaHospital stayRelative riskProcedure timeSevere aortic valve stenosisTranscatheter aortic valve implantationResultsSeven observational studiesAcute kidney injuryProcedure-related mortalityPooled relative riskAortic valve implantationAortic valve stenosisShort-term outcomesShorter procedure timeRandom-effects modelKidney injuryValve implantationOverall mortalityValve stenosisRandomized trialsTransfemoral TAVRLocal anesthesiaTreatment optionsMyocardial infarction
2005
Impact of In-Hospital Acquired Thrombocytopenia in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction
Nikolsky E, Sadeghi HM, Effron MB, Mehran R, Lansky AJ, Na Y, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Stuckey TD, Turco M, Carroll JD, Grines CL, Stone GW. Impact of In-Hospital Acquired Thrombocytopenia in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. The American Journal Of Cardiology 2005, 96: 474-481. PMID: 16098296, DOI: 10.1016/j.amjcard.2005.04.005.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAge DistributionAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalCause of DeathFemaleFollow-Up StudiesHemorrhageHumansImmunoglobulin Fab FragmentsIncidenceInpatientsMaleMiddle AgedMyocardial InfarctionOdds RatioPlatelet Aggregation InhibitorsPlatelet CountProspective StudiesRisk FactorsSex DistributionSurvival RateThrombocytopeniaTreatment OutcomeConceptsPrimary percutaneous coronary interventionPercutaneous coronary interventionAcute myocardial infarctionHemorrhagic complicationsAcquired thrombocytopeniaPlatelet countMyocardial infarctionHigher baseline platelet countGreater body mass indexNadir platelet countPrevious aspirin useUse of abciximabBaseline platelet countBlood product transfusionLonger hospital stayMajor hemorrhagic complicationsHours of onsetBody mass indexAspirin useBaseline thrombocytopeniaCADILLAC trialIschemic complicationsCause mortalityHospital stayPrimary angioplastyContrast-Induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables
Dangas G, Iakovou I, Nikolsky E, Aymong ED, Mintz GS, Kipshidze NN, Lansky AJ, Moussa I, Stone GW, Moses JW, Leon MB, Mehran R. Contrast-Induced nephropathy after percutaneous coronary interventions in relation to chronic kidney disease and hemodynamic variables. The American Journal Of Cardiology 2005, 95: 13-19. PMID: 15619387, DOI: 10.1016/j.amjcard.2004.08.056.Peer-Reviewed Original ResearchConceptsContrast-induced nephropathyChronic kidney diseasePercutaneous coronary interventionIntra-aortic balloon pump useCoronary interventionKidney diseasePump usePredictors of CINPresence of CKDBaseline chronic kidney diseaseLower baseline hematocritBaseline renal functionContrast medium volumeHospital complicationsPeriprocedural hypotensionHospital stayBaseline characteristicsRenal functionConsecutive patientsEjection fractionBaseline hematocritPulmonary edemaHemodynamic variablesHemodynamic parametersPatients
2004
Minimally invasive coronary artery bypass grafting versus stenting for patients with proximal left anterior descending coronary artery disease
Shirai K, Lansky AJ, Mehran R, Dangas GD, Costantini CO, Fahy M, Slack S, Mintz GS, Stone GW, Leon MB. Minimally invasive coronary artery bypass grafting versus stenting for patients with proximal left anterior descending coronary artery disease. The American Journal Of Cardiology 2004, 93: 959-962. PMID: 15081435, DOI: 10.1016/j.amjcard.2003.12.048.Peer-Reviewed Original ResearchConceptsCoronary artery bypassInvasive coronary artery bypassLAD stentingCoronary artery diseaseArtery bypassArtery diseaseClinical outcomesAnterior descending (LAD) coronary artery diseaseConventional coronary artery bypassHigher repeat revascularization ratesQ-wave myocardial infarctionHospital event ratesProximal LAD diseaseRepeat revascularization rateShorter hospital staySubgroup of patientsConventional balloon angioplastyIncidence of deathLong-term efficacyLAD revascularizationMIDCAB groupHospital stayLAD diseaseRevascularization ratesVessel revascularization
2001
Normal Flow (TIMI-3) Before Mechanical Reperfusion Therapy Is an Independent Determinant of Survival in Acute Myocardial Infarction
Stone G, Cox D, Garcia E, Brodie B, Morice M, Griffin J, Mattos L, Lansky A, O’Neill W, Grines C. Normal Flow (TIMI-3) Before Mechanical Reperfusion Therapy Is an Independent Determinant of Survival in Acute Myocardial Infarction. Circulation 2001, 104: 636-641. PMID: 11489767, DOI: 10.1161/hc3101.093701.Peer-Reviewed Original ResearchConceptsTIMI 3 flowAcute myocardial infarctionInitial TIMI 3 flowMyocardial infarctionPrimary PTCAEarly reperfusionHeart failureIndependent determinantsNew-onset heart failurePostprocedural TIMI 3 flowTIMI 3 flow ratesMechanical reperfusion therapyTIMI 0/1 flowTIMI 2 flowProspective randomized trialsShorter hospital stayVentricular ejection fractionInitial angiographyAngiographic evidenceHospital stayLytic therapyReperfusion therapyVentricular failureSpontaneous reperfusionEarly administration
2000
Evolving trends in interventional device use and outcomes: Results from the National Cardiovascular Network database
Peterson E, Lansky A, Anstrom K, Muhlbaier L, Popma J, Satler L, Lanzilotta M, Network F. Evolving trends in interventional device use and outcomes: Results from the National Cardiovascular Network database. American Heart Journal 2000, 139: 198-207. PMID: 10650291, DOI: 10.1016/s0002-8703(00)90226-6.Peer-Reviewed Original ResearchConceptsComplication rateCoronary anatomyAtherectomy devicesInterventional strategiesClinical practiceNew coronary interventional devicesCoronary stentsCoronary interventional devicesCoronary stent usePatient's coronary anatomyPercutaneous interventional strategyPostprocedure hospital stayProcedural success rateOverall mortality rateGeneral clinical practiceNew interventional strategiesDevice usePercentage of casesRotational atherectomy deviceInterventional databasePostprocedure lengthHospital stayCoronary interventionDirectional atherectomyPatient characteristics