2023
Predictors of Neurodevelopment in Microcephaly Associated with Congenital Zika Syndrome: A Prospective Study
Mattos A, Rastely-Junior V, Pires M, Aguilar J, Lessa M, Regis C, Wanderley M, Leony J, Bouzon J, Ballalai V, Vieira C, Carvalho G, Almeida J, Nery N, Leal R, Costa F, Ko A, Reis M, Oliveira-Filho J. Predictors of Neurodevelopment in Microcephaly Associated with Congenital Zika Syndrome: A Prospective Study. Children 2023, 10: 1831. PMID: 38136033, PMCID: PMC10741834, DOI: 10.3390/children10121831.Peer-Reviewed Original ResearchCongenital Zika syndromeEvans indexZika syndromeHead circumferenceNeurodevelopmental delayMedian head circumferenceBayley-III scoresCT scan analysisMicrocephaly AssociatedNeurodevelopmental examinationProspective studyVentricle enlargementBrain abnormalitiesCongenital manifestationsMultiprofessional teamGross motorNeonate periodDevelopmental anomaliesDevelopmental delaySyndromeMicrocephalyBlinded expertsMonthsChildrenCircumference
2022
Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil
Aromolaran A, Araujo K, Ladines-Lim JB, Nery N, do Rosário MS, Rastely VN, Archanjo G, Daltro D, da Silveira Carvalho G, Pimentel K, de Almeida JRM, de Siqueira IC, Ribeiro HC, Oliveira-Filho J, de Oliveira D, Henriques DF, Rodrigues SG, da Costa Vasconcelos P, de Almeida ARP, Sacramento GA, Cruz JS, Sarno M, de Paula Freitas B, Mattos A, Khouri R, Reis MG, Ko AI, Costa F. Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil. International Journal Of Infectious Diseases 2022, 120: 201-204. PMID: 35470025, PMCID: PMC9119857, DOI: 10.1016/j.ijid.2022.04.030.Peer-Reviewed Original ResearchConceptsZIKV exposurePregnant womenSocioeconomic statusRelative disease burdenCongenital Zika syndromeZika virus epidemicLow socioeconomic statusZika syndromeClinical presentationDisease burdenSimilar prevalenceSerologic dataDifferent socioeconomic statusS HospitalHospitalLarge hospitalsMicrocephalyStudy centersVirus epidemicWomenPositive associationInfantsUnequal burdenHigh rateExposure rate
2021
Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly
Ticona J, Nery N, Doss-Gollin S, Gambrah C, Lessa M, Rastely-Júnior V, Matos A, de Paula Freitas B, Borja A, Wunder EA, Ballalai V, Vieira C, Cruz JS, de Oliveira D, Araujo DB, Oliveira DB, Maeda D, Mendes EA, Soares C, Durigon EL, de Souza Ferreira LC, Belfort R, Almeida A, Oliveira-Filho J, Reis MG, Ko AI, Costa F. Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly. PLOS ONE 2021, 16: e0256444. PMID: 34525107, PMCID: PMC8443077, DOI: 10.1371/journal.pone.0256444.Peer-Reviewed Original ResearchConceptsCongenital Zika syndromeHammersmith Infant Neurological ExaminationHINE scoresZika syndromeHead circumferenceBayley-IIILong-term outcomesGreater head circumferenceSevere developmental delayYears of ageSevere neurodevelopmental delayToddler neurodevelopmentNeurological evaluationMedian ageNeurodevelopmental outcomesNeurological examinationMultivariable analysisNeurodevelopmental assessmentOutpatient clinicNeurodevelopmental evaluationNeurodevelopmental delayBayley ScalesNeurodevelopmental profileSevere microcephalyMild delay