2023
Prevalence and Influence of Frailty on Hospital Outcomes After Surgical Resection of Spinal Meningiomas
Elsamadicy A, Koo A, Reeves B, Craft S, Sayeed S, Sherman J, Sarkozy M, Aurich L, Fernandez T, Lo S, Shin J, Sciubba D, Mendel E. Prevalence and Influence of Frailty on Hospital Outcomes After Surgical Resection of Spinal Meningiomas. World Neurosurgery 2023, 173: e121-e131. PMID: 36773810, DOI: 10.1016/j.wneu.2023.02.019.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreLength of stayHealth care resource utilizationSpinal meningiomasNonroutine dischargeAdverse eventsDischarge dispositionInternational ClassificationExtended LOSMean LOSNational Inpatient Sample databaseFrailty Risk ScoreInfluence of frailtyImpact of frailtyRetrospective cohort studyPerioperative adverse eventsTenth Revision codesClinical Modification codesCost of admissionMultivariate regression analysisHospital outcomesPatient frailtyAdult patientsCohort studyPatient demographics
2020
Portending Influence of Racial Disparities on Extended Length of Stay after Elective Anterior Cervical Discectomy and Interbody Fusion for Cervical Spondylotic Myelopathy
Elsamadicy AA, Koo AB, David WB, Sarkozy M, Freedman IG, Reeves BC, Laurans M, Kolb L, Sciubba DM. Portending Influence of Racial Disparities on Extended Length of Stay after Elective Anterior Cervical Discectomy and Interbody Fusion for Cervical Spondylotic Myelopathy. World Neurosurgery 2020, 142: e173-e182. PMID: 32599203, DOI: 10.1016/j.wneu.2020.06.155.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanCerebrospinal Fluid LeakCervical VertebraeCohort StudiesComorbidityDiskectomyElective Surgical ProceduresFemaleHealthcare DisparitiesHumansIntraoperative ComplicationsLength of StayMaleMiddle AgedPostoperative ComplicationsPrevalenceRetrospective StudiesSpinal Cord CompressionSpinal FusionSpondylosisUnited StatesWhite PeopleConceptsCervical spondylotic myelopathyElective anterior cervical discectomyAnterior cervical discectomyAA cohortSpondylotic myelopathyCervical discectomyExtended LOSC cohortSignificant independent risk factorsNational Inpatient Sample databaseLonger hospital stayPrevalence of comorbiditiesRetrospective cohort studyIndependent risk factorNumber of complicationsAfrican AmericansElective ACDFNonroutine dischargeAA raceC patientsHospital stayAdult patientsCohort studyIndependent predictorsAA patientsInfluence of gender on discharge disposition after spinal fusion for adult spine deformity correction
Elsamadicy AA, Freedman IG, Koo AB, David WB, Lee M, Kundishora AJ, Kuzmik GA, Gorrepati R, Hong CS, Kolb L, Laurans M, Abbed K. Influence of gender on discharge disposition after spinal fusion for adult spine deformity correction. Clinical Neurology And Neurosurgery 2020, 194: 105875. PMID: 32388244, DOI: 10.1016/j.clineuro.2020.105875.Peer-Reviewed Original ResearchConceptsDischarge dispositionSpine deformity correctionSpinal fusionFemale cohortMale cohortDeformity correctionElective spine fusion surgeryNon-routine discharge dispositionNationwide Inpatient Sample databaseSpine surgical careSurgical site hematomaNon-routine dischargeElective spinal fusionICD-9 codesSpine fusion surgeryInfluence of genderPostoperative MIPostoperative UTIHospital staySite hematomaHospital factorsIndependent predictorsMale patientsFemale patientsFusion surgery
2019
Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction
Elsamadicy AA, Camara-Quintana J, Kundishora AJ, Lee M, Freedman IG, Long A, Qureshi T, Laurans M, Tomak P, Karikari IO. Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 127: e108-e113. PMID: 30876992, DOI: 10.1016/j.wneu.2019.02.165.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexComorbidityDiabetes MellitusDyslipidemiasElective Surgical ProceduresFemaleHeart DiseasesHumansHypertensionLaminectomyLength of StayMaleMiddle AgedObesityPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPrevalencePulmonary Disease, Chronic ObstructiveRetrospective StudiesSpinal DiseasesSpinal FusionTreatment OutcomeUnited StatesYoung AdultConceptsPatient-reported pain scoresComplex spinal fusionPain scoresImpact of obesityReadmission ratesSurgical outcomesDeformity correctionSpinal fusionAmbulatory statusPatient demographicsComplication ratePreoperative body mass indexPrimary complex spinal fusionShort-term surgical outcomesAdult deformity correctionInferior surgical outcomesPostoperative complication profileLength of surgeryPostoperative complication ratePrevalence of obesityBody mass indexPatient-reported outcomesComplex spinal surgeryPaucity of dataMajor academic institution
2018
Prevalence and Cost Analysis of Chronic Pain After Hernia Repair: A Potential Alternative Approach With Neurostimulation
Elsamadicy AA, Ashraf B, Ren X, Sergesketter AR, Charalambous L, Kemeny H, Ejikeme T, Yang S, Pagadala P, Parente B, Xie J, Pappas TN, Lad SP. Prevalence and Cost Analysis of Chronic Pain After Hernia Repair: A Potential Alternative Approach With Neurostimulation. Neuromodulation Technology At The Neural Interface 2018, 22: 960-969. PMID: 30320933, PMCID: PMC6465156, DOI: 10.1111/ner.12871.Peer-Reviewed Original ResearchConceptsChronic painInpatient/outpatientHernia repairPrescription costsCP cohortOutpatient costsIndex hernia repairPrevalence of CPChronic pain cohortHealthcare resource utilizationHealth care utilizationCurrent treatment paradigmsRetrospective longitudinal studyYears of ageLongitudinal multivariate analysisNonopioid treatmentPain prescriptionsCP diagnosisPain cohortCare utilizationDiagnosis yearTruven MarketScanPain diagnosisTreatment paradigmInclusion criteriaIndependent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients.
Elsamadicy AA, Ren X, Kemeny H, Charalambous L, Sergesketter AR, Rahimpour S, Williamson T, Goodwin CR, Abd-El-Barr MM, Gottfried ON, Xie J, Lad SP. Independent Associations With 30- and 90-Day Unplanned Readmissions After Elective Lumbar Spine Surgery: A National Trend Analysis of 144 123 Patients. Neurosurgery 2018, 84: 758-767. PMID: 29893899, DOI: 10.1093/neuros/nyy215.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryChronic obstructive pulmonary disorderLumbar spine surgeryNational Readmission DatabaseUnplanned hospital readmissionPatient risk factorsUnplanned readmissionHospital readmissionSpine surgeryDeficiency anemiaInsurance statusRisk factorsElective spinal surgeryUnplanned readmission rateObstructive pulmonary disorderMultivariate regression analysisPaucity of dataInpatient complicationsNational healthcare expendituresReadmission ratesDural tearPulmonary disordersIndependent associationPatient outcomesSpinal surgeryInfluence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery.
Elsamadicy AA, Kemeny H, Adogwa O, Sankey EW, Goodwin CR, Yarbrough CK, Lad SP, Karikari IO, Gottfried ON. Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery. Journal Of Neurosurgery Spine 2018, 29: 40-45. PMID: 29701564, DOI: 10.3171/2017.12.spine171079.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanDiagnostic Self EvaluationDisability EvaluationElective Surgical ProceduresFemaleHealth StatusHealthcare DisparitiesHumansLumbar VertebraeMaleMiddle AgedPainPatient Reported Outcome MeasuresPatient SatisfactionPrevalenceProspective StudiesRetrospective StudiesSelf ConceptTime FactorsWhite PeopleConceptsElective lumbar spine surgeryPatient-reported outcomesLumbar spine surgerySpine surgeryPatient satisfactionRacial disparitiesPatient demographicsReadmission ratesWhite patientsAA patientsMedical recordsLong-term patient-reported outcomesOverall patient-reported outcomeGreater body mass indexBaseline patient demographicsInferior surgical outcomesVAS-LP scoresPatient-reported satisfactionOverall patient satisfactionBody mass indexVisual analog scaleAfrican American patientsPatient-specific factorsPatient satisfaction measuresPerception of health
2017
Prevalence, healthcare resource utilization and overall burden of fungal meningitis in the United States
Charalambous LT, Premji A, Tybout C, Hunt A, Cutshaw D, Elsamadicy AA, Yang S, Xie J, Giamberardino C, Pagadala P, Perfect JR, Lad SP. Prevalence, healthcare resource utilization and overall burden of fungal meningitis in the United States. Journal Of Medical Microbiology 2017, 67: 215-227. PMID: 29244019, PMCID: PMC6557145, DOI: 10.1099/jmm.0.000656.Peer-Reviewed Original ResearchConceptsHealthcare resource utilizationFungal meningitisCryptococcal meningitisMeningitis patientsTruven Health Analytics MarketScan databaseLong-term morbidityLength of stayLarge longitudinal cohortHealth economic impactCandida meningitisLong followMarketScan databasePrimary diagnosisLongitudinal cohortOverall burdenCandidiasis patientsMeningitisHistoplasmosis patientsMeningitis diagnosisPatientsOriginal diagnosisSingle pathogenPrevalent typeDiagnosisUnited StatesThe Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesPrevalence and Cost Analysis of Complex Regional Pain Syndrome (CRPS): A Role for Neuromodulation
Elsamadicy AA, Yang S, Sergesketter AR, Ashraf B, Charalambous L, Kemeny H, Ejikeme T, Ren X, Pagadala P, Parente B, Xie J, Lad SP. Prevalence and Cost Analysis of Complex Regional Pain Syndrome (CRPS): A Role for Neuromodulation. Neuromodulation Technology At The Neural Interface 2017, 21: 423-430. PMID: 28961359, PMCID: PMC5876058, DOI: 10.1111/ner.12691.Peer-Reviewed Original ResearchConceptsComplex regional pain syndromeRegional pain syndromeCRPS diagnosisPain prescriptionsPain syndromeBaseline costsMedian costDiagnosis of CRPSOne-yearHealthcare resource utilizationHealthcare utilization costsOverall cost burdenRetrospective longitudinal studyPaucity of dataLongitudinal multivariate analysisUS healthcare systemBaseline characteristicsCRPS patientsTruven MarketScanPrescription costsTotal cumulative costsDiagnosis periodPatientsMultivariate analysisOutpatientsPrevalence of Specific Types of Pain Diagnoses in a Sample of United States Adults.
Murphy KR, Han JL, Yang S, Hussaini SM, Elsamadicy AA, Parente B, Xie J, Pagadala P, Lad SP. Prevalence of Specific Types of Pain Diagnoses in a Sample of United States Adults. Pain Physician 2017, 20: e257-e268. PMID: 28158163, DOI: 10.36076/ppj.2017.e268.Peer-Reviewed Original ResearchConceptsDegenerative spine diseasePain diagnosisPain conditionsLimb painBack painChronic painSpine diseaseComplex regional pain syndromePost-laminectomy painPost-laminectomy syndromeUnited States patient populationMedicare Supplemental databasesChronic pain conditionsRegional pain syndromeNon-randomized studiesSpecific pain diagnosesUnited States adultsHealth care servicesPain syndromePain patientsPatient populationTruven MarketScanPatient cohortRetrospective analysisPain
2016
Drivers of 30-Day Readmission in Elderly Patients (>65 Years Old) After Spine Surgery: An Analysis of 500 Consecutive Spine Surgery Patients
Adogwa O, Elsamadicy AA, Han J, Karikari IO, Cheng J, Bagley CA. Drivers of 30-Day Readmission in Elderly Patients (>65 Years Old) After Spine Surgery: An Analysis of 500 Consecutive Spine Surgery Patients. World Neurosurgery 2016, 97: 518-522. PMID: 27474458, DOI: 10.1016/j.wneu.2016.07.032.Peer-Reviewed Original ResearchConceptsElective spine surgerySpine surgeryUnplanned readmissionEarly readmissionElderly patientsHospital stayConsecutive spine surgery patientsCauses of readmissionSpine surgery patientsDays of dischargeMajority of patientsCommon primary reasonsSkilled nursing facilitiesQuality of carePaucity of dataMajor academic hospitalNonsurgical complicationsSD ageSurgery patientsEmergency departmentMental statusAcademic hospitalCommon causeReadmissionNursing facilities