2023
Management of dynamic cervical kyphosis with dorsal epidural lipomatosis: a Hirayama disease variant? Illustrative case
Kundishora A, Reeves B, Moreno-De-Luca A, Hong C, Robert S, Elsamadicy A, Tuason D, DiLuna M. Management of dynamic cervical kyphosis with dorsal epidural lipomatosis: a Hirayama disease variant? Illustrative case. Journal Of Neurosurgery Case Lessons 2023, 5: case22481. PMID: 36880508, PMCID: PMC10550661, DOI: 10.3171/case22481.Peer-Reviewed Original ResearchCervical kyphosisHirayama diseaseMagnetic resonance imagingSelf-limiting natureTwo-level anterior cervical discectomySpinal magnetic resonance imagingNormal cervical lordosisAggressive surgical managementAnterior cervical discectomySpinal cord compressionPosterior spinal fusionProgressive paresthesiaCord compressionSurgical decompressionCervical discectomyCervical myelopathyEpidural lipomatosisCervical immobilizationMRI findingsCervical lordosisSurgical managementCervical collarCharacteristic findingsRare entityTreatment options
2020
Laser interstitial thermal therapy (LITT) vs. bevacizumab for radiation necrosis in previously irradiated brain metastases
Sujijantarat N, Hong CS, Owusu KA, Elsamadicy AA, Antonios JP, Koo AB, Baehring JM, Chiang VL. Laser interstitial thermal therapy (LITT) vs. bevacizumab for radiation necrosis in previously irradiated brain metastases. Journal Of Neuro-Oncology 2020, 148: 641-649. PMID: 32602021, DOI: 10.1007/s11060-020-03570-0.Peer-Reviewed Original ResearchConceptsLaser interstitial thermal therapyLonger overall survivalRadiation necrosisInterstitial thermal therapyBrain metastasesOverall survivalMedian volume decreaseMedian volume increaseBrain metastasis patientsPre-treatment patient characteristicsRetrospective chart reviewResultsTwenty-five patientsPre-treatment factorsBevacizumab patientsChart reviewMetastasis patientsLocal recurrencePatient characteristicsTreatment optionsTreatment responseBevacizumabPatientsLesional volumeThermal therapyStatistical significancePersistent STAG2 mutation despite multimodal therapy in recurrent pediatric glioblastoma
Hong CS, Vasquez JC, Kundishora AJ, Elsamadicy AA, Beckta JM, Sule A, Marks AM, Leelatian N, Huttner A, Bindra RS, DiLuna ML, Kahle KT, Erson-Omay EZ. Persistent STAG2 mutation despite multimodal therapy in recurrent pediatric glioblastoma. Npj Genomic Medicine 2020, 5: 23. PMID: 32528726, PMCID: PMC7264170, DOI: 10.1038/s41525-020-0130-7.Peer-Reviewed Original ResearchPediatric patientsStandard chemoradiationSTAG2 mutationsTumor clonesPediatric glioblastomaGross total resectionMultiple surgical resectionsTime of recurrenceHigh-grade gliomasDNA damage repair defectsWhole-exome sequencingVariety of treatmentsSurgical resectionNovel deleterious mutationsStandard therapyTotal resectionVaccine therapyClinical evidencePreclinical dataTreatment optionsMultimodal therapyPreclinical studiesClinical settingTherapyAdult counterparts
2017
Long-term Cost Utility of Spinal Cord Stimulation in Patients with Failed Back Surgery Syndrome.
Farber SH, Han JL, Elsamadicy AA, Hussaini Q, Yang S, Pagadala P, Parente B, Xie J, Lad SP. Long-term Cost Utility of Spinal Cord Stimulation in Patients with Failed Back Surgery Syndrome. Pain Physician 2017, 20: e797-e805. PMID: 28934786, PMCID: PMC8358894, DOI: 10.36076/ppj.20.5.e797.Peer-Reviewed Original ResearchConceptsConventional medical managementSpinal cord stimulationFBSS patientsSurgery syndromeCord stimulationSCS systemCost utilityFailed Back Surgery SyndromeBack surgery syndromePrior back surgeryGEE modelHealth care utilizationRandomized clinical trialsConventional managementLongitudinal GEE modelsTime of implantationLeg painSCS implantationBack painCare utilizationLong followMedical managementSignificant morbidityBack surgeryTreatment options