2024
Efficacy and utility of antifibrinolytics in pediatric spine surgery: a systematic review and network meta-analysis
Aghajanian S, Mohammadifard F, Kohandel Gargari O, Naeimi A, Bahadorimonfared A, Elsamadicy A. Efficacy and utility of antifibrinolytics in pediatric spine surgery: a systematic review and network meta-analysis. Neurosurgical Review 2024, 47: 177. PMID: 38644447, DOI: 10.1007/s10143-024-02424-x.Peer-Reviewed Original ResearchConceptsNetwork meta-analysisRate of complicationsBlood lossSpine surgeryEpsilon-aminocaproic acidMeta-analysisTranexamic acidEfficacy of antifibrinolyticsPediatric spine surgeryPerioperative blood lossReduce blood lossStandardized outcome dataRandomized clinical trialsStandard of carePerioperative bleedingTransfusion volumeTransfusion rateAntifibrinolytic agentsMassive transfusionPediatric patientsSafety profilePediatric surgeryProbability of efficacyAntifibrinolyticsClinical trials
2020
Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction.
Elsamadicy AA, Adil SM, Charalambous L, Drysdale N, Koo AB, Lee M, Kundishora AJ, Camara-Quintana J, Kolb L, Laurans M, Abbed K, Karikari IO. Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction. Spine 2020, 45: 268-274. PMID: 31996654, DOI: 10.1097/brs.0000000000003260.Peer-Reviewed Original ResearchConceptsIntraoperative blood transfusionComplex spinal fusionAllogenic blood transfusionPostoperative deliriumBlood transfusionSpinal fusionIndependent associationDeformity correctionMultivariate nominal-logistic regression analysisPrimary complex spinal fusionAdult spine deformity patientsAdult deformity correctionBetter overall patient careGreater complication risksRetrospective cohort studySpine deformity patientsOverall patient careNominal logistic regression analysisMajor academic institutionHospital stayCohort studyBlood lossPrimary outcomeComplication riskDeformity patients
2019
Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction.
Elsamadicy AA, Lubkin DT, Sergesketter AR, Adil SM, Charalambous LT, Drysdale N, Williamson T, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction. Journal Of Neurosurgery Spine 2019, 30: 376-381. PMID: 30641841, DOI: 10.3171/2018.9.spine18686.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionSpinal fusionSpine surgeryDeformity correctionAdult deformity correctionCost-conscious healthcareMethodsThe medical recordsPostoperative complication rateMean lengthBody mass indexFollow-up radiographsRevision of surgeryComplex spine surgeryMajor academic institutionHospital stayAdult patientsComplication ratePatient demographicsReadmission ratesBlood lossPrimary outcomeMass indexEarly radiographsPostoperative radiographs
2017
Assessing the effectiveness of routine use of post-operative in-patient physical therapy services
Adogwa O, Elsamadicy AA, Fialkoff J, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Assessing the effectiveness of routine use of post-operative in-patient physical therapy services. Journal Of Spine Surgery 2017, 3: 149-154. PMID: 28744494, PMCID: PMC5506300, DOI: 10.21037/jss.2017.04.03.Peer-Reviewed Original ResearchHospital stayPhysical therapy servicesComplication ratePT cohortTherapy servicesPeri-operative complication ratesPost-operative complication rateRoutine useElective spine surgeryPost-operative ambulationPeri-operative complicationsMajor academic medical centerProlonged bed restAcademic medical centerPT servicesImproved ambulationPerioperative complicationsBaseline characteristicsHospital dischargePatient demographicsReadmission ratesBlood lossAmbulation statusOperative timeRisk stratificationEffects of immediate post-operative pain medication on length of hospital stay: does it make a difference?
Elsamadicy AA, Adogwa O, Fialkoff J, Vuong VD, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Effects of immediate post-operative pain medication on length of hospital stay: does it make a difference? Journal Of Spine Surgery 2017, 3: 155-162. PMID: 28744495, PMCID: PMC5506320, DOI: 10.21037/jss.2017.04.04.Peer-Reviewed Original ResearchPost-operative pain medicationPatient reported outcomesElective spine surgeryPain medicationUrinary tract infectionSpine surgeryHospital stayComplication ratePatient carePost-operative complication rateSignificant differencesDecreased pain scoresHospital readmission ratesPatient-controlled analgesicMajor academic medical centerAcademic medical centerHealth care costsHealth care dollarsHospital coursePain scoresBaseline characteristicsPatient demographicsReadmission ratesTract infectionsBlood lossIncreased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study
Elsamadicy AA, Adogwa O, Warwick H, Sergesketter A, Lydon E, Shammas RL, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Increased 30-Day Complication Rates Associated with Laminectomy in 874 Adult Patients with Spinal Deformity Undergoing Elective Spinal Fusion: A Single Institutional Study. World Neurosurgery 2017, 102: 370-375. PMID: 28359921, DOI: 10.1016/j.wneu.2017.03.096.Peer-Reviewed Original ResearchConceptsElective spinal fusionSpinal fusionSpinal deformityAdult patientsComplication rateComplication Rates AssociatedAllogeneic blood transfusionPostoperative complication rateSingle institutional studyUrinary tract infectionHigh complication rateIntensive care unitMajor academic institutionPatient demographicsReadmission ratesTract infectionsBlood lossBlood transfusionPrimary outcomeWound drainageCare unitIntraoperative durotomyMedical recordsMental statusInstrumentation failureEffect of employment status on length of hospital stay, 30-day readmission and patient reported outcomes after spine surgery
Adogwa O, Elsamadicy AA, Fialkoff J, Mehta AI, Vasquez RA, Cheng J, Karikari IO, Bagley CA. Effect of employment status on length of hospital stay, 30-day readmission and patient reported outcomes after spine surgery. Journal Of Spine Surgery 2017, 3: 44-49. PMID: 28435917, PMCID: PMC5386895, DOI: 10.21037/jss.2017.03.08.Peer-Reviewed Original ResearchElective spine surgeryHospital staySpine surgeryReadmission ratesComplication ratePatient cohortFunctional improvementPeri-operative complication ratesPost-operative complication rateEmployment statusUnplanned hospital readmissionDays of dischargeGreater functional improvementMajor academic medical centerAcademic medical centerCause readmissionBaseline characteristicsPatient demographicsBlood lossHospital readmissionPrimary outcomeReadmission preventionUnemployed patientsOperative timeMedical recordsImpact of Obesity on Complications and 30-Day Readmission Rates After Cranial Surgery: A Single-Institutional Study of 224 Consecutive Craniotomy/Craniectomy Procedures
Sergesketter A, Elsamadicy AA, Gottfried ON. Impact of Obesity on Complications and 30-Day Readmission Rates After Cranial Surgery: A Single-Institutional Study of 224 Consecutive Craniotomy/Craniectomy Procedures. World Neurosurgery 2017, 100: 244-249. PMID: 28093346, DOI: 10.1016/j.wneu.2017.01.019.Peer-Reviewed Original ResearchConceptsImpact of obesityBody mass indexReadmission ratesCranial surgeryPostoperative complicationsMass indexSurgical outcomesPreoperative body mass indexMean body mass indexBaseline patient characteristicsEffect of obesityPrevalence of obesityMajor academic institutionHospital stayMost patientsObese cohortObese patientsPatient characteristicsSurgical complicationsBlood lossConsecutive patientsNonobese cohortPrimary outcomeTumor excisionMedical records