Association of Histologic Findings With Long-Term Outcomes in Symptomatic Obstructive Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy
Jadam S, Gaballa A, Alashi A, Xu B, Thamilarasan M, Rodriguez E, Tan C, Ospina S, Smedira N, Popovic Z, Desai M. Association of Histologic Findings With Long-Term Outcomes in Symptomatic Obstructive Hypertrophic Cardiomyopathy Patients Undergoing Surgical Myectomy. JACC Heart Failure 2024 PMID: 39545888, DOI: 10.1016/j.jchf.2024.10.006.Peer-Reviewed Original ResearchObstructive hypertrophic cardiomyopathySurgical myectomyLong-term outcomesMyocyte hypertrophyInterstitial fibrosisHistological findingsHypertrophic cardiomyopathyObstructive hypertrophic cardiomyopathy patientsHistological scoresAssociated with long-term outcomesSevere histological findingsHypertrophic cardiomyopathy patientsKaplan-Meier analysisMultivariate Cox analysisLeft ventricular hypertrophyComposite of deathPrimary eventDiastolic dysfunctionCardiac transplantationPrimary endpointTertiary centerCardiomyopathy patientsMicrovascular ischemiaVentricular hypertrophyCox analysis