Featured Publications
Beyond implantation effect? Long-term seizure reduction and freedom following intracranial monitoring without additional surgical interventions
Percy J, Zaveri H, Duckrow RB, Gerrard J, Farooque P, Hirsch LJ, Spencer DD, Sivaraju A. Beyond implantation effect? Long-term seizure reduction and freedom following intracranial monitoring without additional surgical interventions. Epilepsy & Behavior 2020, 111: 107231. PMID: 32615416, DOI: 10.1016/j.yebeh.2020.107231.Peer-Reviewed Original ResearchConceptsLong-term seizure freedomSeizure freedomSeizure frequencyElectrode implantationIntracranial studiesLong-term seizure reductionAdditional surgical interventionSeizure onset localizationIntracranial electroencephalogram monitoringSeizure reductionConsecutive patientsSurgical interventionEpileptogenic networksElectroencephalogram monitoringNeuromodulatory effectsRetrospective analysisIntracranial monitoringTransient improvementDepth electrodesPatientsYear 4ImplantationAdequate dataYearsPrognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome
Sivaraju A, Gilmore EJ, Wira CR, Stevens A, Rampal N, Moeller JJ, Greer DM, Hirsch LJ, Gaspard N. Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome. Intensive Care Medicine 2015, 41: 1264-1272. PMID: 25940963, DOI: 10.1007/s00134-015-3834-x.Peer-Reviewed Original ResearchConceptsBetter outcomesPoor outcomeEpileptiform dischargesPost-cardiac arrest comatose patientsCritical care EEG terminologyPost-cardiac arrest comaMethodsProspective cohort studyContinuous EEG monitoringLow-voltage EEGPositive predictive valueAbsence of reactivityEEG terminologyCohort studySpontaneous circulationBrainstem reflexesClinical outcomesComatose patientsFalse positive ratePoor prognosisPrognostic significanceSuppression burstsClinical variablesClinical correlatesElectroencephalographic patternsElectroencephalographic predictors
2024
Predictors of follow-up care for critically-ill patients with seizures and epileptiform abnormalities on EEG monitoring
Rice H, Fernandes M, Punia V, Rubinos C, Sivaraju A, Zafar S. Predictors of follow-up care for critically-ill patients with seizures and epileptiform abnormalities on EEG monitoring. Clinical Neurology And Neurosurgery 2024, 241: 108275. PMID: 38640778, PMCID: PMC11167629, DOI: 10.1016/j.clineuro.2024.108275.Peer-Reviewed Original ResearchConceptsNeurological follow-upFollow-up visitFollow-upAntiseizure medicationsOutpatient follow-upCritically-ill patientsContinuous EEGEpileptiform abnormalitiesPredictors of follow-upPrevent long-term complicationsIllness severityYounger ageRetrospective cohort studyLong-term complicationsFollow-up statusIntensive care unitProbability of follow-upHigher illness severityPredictors of readmissionContinuous EEG recordingsRisk stratificationEEG monitoringCohort studyCritically-illCare unitSeizing Control: Primary Visual Cortex Epilepsy Treated With Resection and Responsive Neurostimulation: 2-Dimensional Operative Video
Merenzon M, Lamsam L, McGrath H, Sivaraju A, Hirsch L, Cukiert A, Zibly Z, Spencer D, Damisah E. Seizing Control: Primary Visual Cortex Epilepsy Treated With Resection and Responsive Neurostimulation: 2-Dimensional Operative Video. Operative Neurosurgery 2024, 27: 262-263. PMID: 39007609, DOI: 10.1227/ons.0000000000001109.Peer-Reviewed Original Research
2023
Impact of acute symptomatic seizures and their management on patient-reported outcomes after stroke
Punia V, Li Y, Lapin B, Chandan P, Newey C, Hantus S, Dhakar M, Rubinos C, Zafar S, Sivaraju A, Katzan I, investigators F. Impact of acute symptomatic seizures and their management on patient-reported outcomes after stroke. Epilepsy & Behavior 2023, 140: 109115. PMID: 36804847, DOI: 10.1016/j.yebeh.2023.109115.Peer-Reviewed Original ResearchConceptsPatient-reported outcome measuresAnti-seizure medicationsAcute symptomatic seizuresOutcome measuresSymptomatic seizuresHospital dischargeASM useExact testFirst patient-reported outcome measureRetrospective cohort studyPatient-reported outcomesStandard of careContinuous EEG monitoringFisher's exact testWilcoxon rank sum testChi-square testRank sum testPROM completionStroke clinicCohort studyRecent strokeStroke patientsNeuro-QoLPhysical functionPatientsTransfrontal Approach to the Amygdala for Ablation With Laser Interstitial Thermal Therapy: An Epilepsy Case Report
Lamsam L, Brigido M, Sivaraju A, Hirsch L, Spencer D, Chiang V, Damisah E. Transfrontal Approach to the Amygdala for Ablation With Laser Interstitial Thermal Therapy: An Epilepsy Case Report. Operative Neurosurgery 2023, 24: e381-e384. PMID: 36715982, PMCID: PMC10158899, DOI: 10.1227/ons.0000000000000576.Peer-Reviewed Original ResearchConceptsStereotactic laser amygdalohippocampotomyLaser interstitial thermal therapyEntorhinal cortexInterstitial thermal therapyComplete ablationMesial temporal lobe epilepsyTemporal arteriovenous malformationTemporal lobe epilepsyLeft temporal arteriovenous malformationMiddle frontal gyrusPrior craniotomyOpen resectionLobe epilepsyCase reportMedial amygdalaArteriovenous malformationsAnterior entorhinal cortexTransfrontal approachAmygdalaInvasive surgeryFrontal gyrusThermal therapyIntracranial electroencephalographyResection
2021
Gerstmann Syndrome Deconstructed by Cortical Stimulation
Vaddiparti A, McGrath H, Benjamin C, Sivaraju A, Spencer DD, Hirsch LJ, Damisah E, Quraishi IH. Gerstmann Syndrome Deconstructed by Cortical Stimulation. Neurology 2021, 97: 420-422. PMID: 34187861, PMCID: PMC9246017, DOI: 10.1212/wnl.0000000000012441.Peer-Reviewed Original Research
2008
Increased beat-to-beat ‘R’ amplitude variability in patients with panic disorder
Yeragani V, Chokka P, Tancer M, Sivaraju A, Bar K. Increased beat-to-beat ‘R’ amplitude variability in patients with panic disorder. International Journal Of Cardiology 2008, 143: 431-432. PMID: 19097657, DOI: 10.1016/j.ijcard.2008.12.003.Peer-Reviewed Original Research