1996
Function and expression of a human idiotypic network in Schistosomiasis japonica
WISNEWSKI A, OLDS G, JOHNSON J, RAMIREZ B, KRESINA T. Function and expression of a human idiotypic network in Schistosomiasis japonica. Parasite Immunology 1996, 18: 439-447. PMID: 9226679, DOI: 10.1111/j.1365-3024.1996.tb01027.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsAntibodies, Anti-IdiotypicAntibodies, HelminthAntibodies, HeterophileAntigens, HelminthChildFemaleGranulomaHumansImmunoglobulin GImmunoglobulin IdiotypesIn Vitro TechniquesLymphocyte ActivationMiceOvumPregnancySchistosoma japonicumSchistosomiasis japonicaSolubilityT-LymphocytesConceptsS. japonicum soluble egg antigensAnti-idiotypic antibodiesSchistosomiasis japonicaHuman anti-idiotypic antibodySoluble egg antigenNon-related antigensAnti-idiotypic antiseraS. japonicum infectionHuman lymphocyte blastogenesisCross-reactive idiotypeDose-dependent mannerHepatosplenic diseaseAcute infectionSerum levelsBlastogenic responseLymphocyte blastogenesisEgg antigenImmunoregulatory networkGranuloma formationJaponicum infectionFormation assaysS. japonicumAntibodiesAntigenDependent manner
1994
Induction Of Hepatic Pathology In Scid-Hu Mice Engrafted With Peripheral Blood Lymphocytes Of Patients With Schistosomiasis Japonica
Kresina T, Wisnewski A, Love-Homan L, Ramirez B, Neil G. Induction Of Hepatic Pathology In Scid-Hu Mice Engrafted With Peripheral Blood Lymphocytes Of Patients With Schistosomiasis Japonica. The Journal Of Infectious Diseases 1994, 170: 733-736. PMID: 8077739, DOI: 10.1093/infdis/170.3.733.Peer-Reviewed Original ResearchConceptsPeripheral blood lymphocytesSCID-hu miceHepatic pathologyBlood lymphocytesActivation of PBLSerum profileSoluble worm antigenic preparationTh1 phenotype cytokinesTh2 phenotype cytokinesInflammatory cell infiltrateSoluble egg antigenHuman immune responseSchistosomiasis japonica infectionHuman cytokine profilesCytokine profileCell infiltrateEgg antigenClinical examinationIL-4SCID miceImmune responseGamma interferonSpecific cytokinesSchistosomiasis japonicaAntigenic preparations
1991
An immunoregulatory human monoclonal antibody in schistosomiasis japonica
Kresina T, Guan X, Posner M, Wisnewski A, Olds G. An immunoregulatory human monoclonal antibody in schistosomiasis japonica. Human Antibodies 1991, 2: 42-45. PMID: 1651785, DOI: 10.3233/hab-1991-2107.Peer-Reviewed Original ResearchConceptsHuman monoclonal antibodyMonoclonal antibodiesEgg antigenAntigen-induced blastogenesisAdult wormsEpstein-Barr virusSoluble egg antigenOS cell linesWestern blot analysisChronic schistosomiasisSoluble eggBarr virusChinese patientsChronic diseasesAntibody-producing hybridomasAntigen reactivitySchistosomiasis japonicaCarbohydrate antigensWestern blotDecompression operationMurine splenocytesSplenocytesAntibodiesAntigenSchistosoma japonicum