2013
Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate
Wisnewski AV, Liu J. Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate. Molecular Immunology 2013, 54: 233-237. PMID: 23295252, PMCID: PMC3563841, DOI: 10.1016/j.molimm.2012.11.017.Peer-Reviewed Original ResearchConceptsEpitope specificityAutologous serum proteinsLow molecular weight chemicalsOccupational asthmaOccupational allergensMolecular determinantsDisease pathogenesisSecreting clonesCDR3 regionWestern blotGene usageMonoclonal antibodiesMajor causeWeight chemicalsIgG1 mAbGermline gene usageHuman albuminImmune specificityMAbsSerum proteinsELISADiagnostic reagentsUseful diagnostic reagentHybridomasSomatic hypermutation
1996
Human antibody variable region gene usage in HIV-1 infection.
Wisnewski A, Cavacini L, Posner M. Human antibody variable region gene usage in HIV-1 infection. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1996, 11: 31-8. PMID: 8528730, DOI: 10.1097/00042560-199601010-00004.Peer-Reviewed Original ResearchConceptsHIV-1 infectionHIV-1 pathogenesisVariable region gene usageRegion gene usageGene usageHuman immunodeficiency virus type 1 (HIV-1) infectionHIV-1-infected patientsVirus type 1 infectionHuman humoral immune responseAnti-HIV-1 antibodiesDifferent lymphoid compartmentsType 1 infectionHumoral immune responsePeripheral blood lymphocytesPolymerase chain reaction studiesHuman monoclonal antibodyAIDS patientsInfected patientsBlood lymphocytesLymphoid compartmentsGene expressionHIV-1Immune responseSerum IgSerological studies