2019
Altered functional connectivity and low-frequency signal fluctuations in early psychosis and genetic high risk
Tang Y, Zhou Q, Chang M, Chekroud A, Gueorguieva R, Jiang X, Zhou Y, He G, Rowland M, Wang D, Fu S, Yin Z, Leng H, Wei S, Xu K, Wang F, Krystal JH, Driesen NR. Altered functional connectivity and low-frequency signal fluctuations in early psychosis and genetic high risk. Schizophrenia Research 2019, 210: 172-179. PMID: 30685394, DOI: 10.1016/j.schres.2018.12.041.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCerebral CortexConnectomeFemaleGenetic Predisposition to DiseaseHumansMagnetic Resonance ImagingMalePsychotic DisordersRiskSchizophreniaYoung AdultConceptsFunctional connectivityHigh-risk individualsAltered functional connectivityHealthy comparison subjectsGenetic high riskGenetic high-risk individualsLow-frequency signal fluctuationsFunctional magnetic resonanceALFF abnormalitiesALFF measuresFunctional connectivity measuresBasal gangliaFirst episodeHigh riskEarly psychosisComparison subjectsSchizophrenia diathesisSchizophrenia vulnerabilityFESzGenetic riskLow-frequency fluctuationsIllnessSchizophreniaVoxel connectivityGHR
2018
Reading the (functional) writing on the (structural) wall: Multimodal fusion of brain structure and function via a deep neural network based translation approach reveals novel impairments in schizophrenia
Plis SM, Amin MF, Chekroud A, Hjelm D, Damaraju E, Lee HJ, Bustillo JR, Cho K, Pearlson GD, Calhoun VD. Reading the (functional) writing on the (structural) wall: Multimodal fusion of brain structure and function via a deep neural network based translation approach reveals novel impairments in schizophrenia. NeuroImage 2018, 181: 734-747. PMID: 30055372, PMCID: PMC6321628, DOI: 10.1016/j.neuroimage.2018.07.047.Peer-Reviewed Original ResearchMeSH KeywordsAdultConnectomeDeep LearningFemaleGray MatterHumansMagnetic Resonance ImagingMaleMiddle AgedNerve NetPsychotic DisordersSchizophreniaConceptsGray matter patternsIntrinsic connectivity networksPosterior cingulate cortexHealthy controlsDynamic functional connectivityStructural MRIFunctional MRIDFNC statesGray matter densitySignificant group differencesTemporal lobeTemporal cortexCingulate cortexSame brainFunctional connectivityBrain structuresCognitive scoresStrong associationLinkage/associationMultimodal brain imaging dataImaging dataGroup differencesSignificant correlationSMRI dataCortex
2016
Altered functional brain connectivity in children and young people with opsoclonus–myoclonus syndrome
Chekroud A, Anand G, Yong J, Pike M, Bridge H. Altered functional brain connectivity in children and young people with opsoclonus–myoclonus syndrome. Developmental Medicine & Child Neurology 2016, 59: 98-104. PMID: 27658927, DOI: 10.1111/dmcn.13262.Peer-Reviewed Original ResearchConceptsOpsoclonus-myoclonus syndromeMagnetic resonance imagingMotor cortexOccipito-parietal regionsAltered functional brain connectivityWidespread brain involvementResting-state functional MRI dataComparison groupStructural brain changesCross-sectional studyFunctional brain connectivitySeed-based analysisBrain functional connectivityAge-matched comparison participantsBrain involvementMotor sequelaeBasal gangliaBrain changesPatientsResonance imagingBrain regionsFunctional MRI dataFunctional connectivityVisual networkBrain connectivity
2014
Cerebellar and cortical abnormalities in paediatric opsoclonus‐myoclonus syndrome
Anand G, Bridge H, Rackstraw P, Chekroud A, Yong J, Stagg C, Pike M. Cerebellar and cortical abnormalities in paediatric opsoclonus‐myoclonus syndrome. Developmental Medicine & Child Neurology 2014, 57: 265-272. PMID: 25290446, DOI: 10.1111/dmcn.12594.Peer-Reviewed Original ResearchConceptsOpsoclonus-myoclonus syndromePediatric opsoclonus-myoclonus syndromeGray matter volumeCortical thicknessDiffusion-weighted imagesCerebellar atrophyFlocculonodular lobeMatter volumeMagnetic resonance spectroscopy scansCerebral cortical thicknessTract-based spatial statisticsT1-weighted structural imagesCerebellar gray matter volumeWhole-brain levelWhole-brain analysisWhite matter integrityCerebellar gray matterPersistent symptomatologyClinical outcomesMotor sequelaeChronic phaseCortical abnormalitiesMotor cortexBrain levelsOMS group