2021
Parsing the antidepressant effects of non-invasive brain stimulation and pharmacotherapy: A symptom clustering approach on ELECT-TDCS
Goerigk S, Padberg F, Chekroud A, Kambeitz J, Bühner M, Brunoni A. Parsing the antidepressant effects of non-invasive brain stimulation and pharmacotherapy: A symptom clustering approach on ELECT-TDCS. Brain Stimulation 2021, 14: 906-912. PMID: 34048940, DOI: 10.1016/j.brs.2021.05.008.Peer-Reviewed Original ResearchMeSH KeywordsAntidepressive AgentsBrainCluster AnalysisDepressive Disorder, MajorDouble-Blind MethodHumansTranscranial Direct Current StimulationTreatment OutcomeConceptsTranscranial direct current stimulationNon-invasive brain stimulationDepressive symptomsBrain stimulationEfficacy of tDCSCore depressive symptomsLinear mixed regression modelsDepressive symptom clustersConsiderable inter-individual variabilityDirect current stimulationEscitalopram 20Antidepressant effectsAntidepressant efficacyInter-individual variabilityAtypical symptomsDepressed patientsMixed regression modelsInsomnia symptomsTDCS sessionsPharmacotherapyEscitalopramSymptomsPlaceboSymptom clustersCurrent stimulation
2020
Precision non-implantable neuromodulation therapies: a perspective for the depressed brain
Borrione L, Bellini H, Razza L, Avila A, Baeken C, Brem A, Busatto G, Carvalho A, Chekroud A, Daskalakis Z, Deng Z, Downar J, Gattaz W, Loo C, Lotufo P, da Graça M. Martin M, McClintock S, O’Shea J, Padberg F, Passos I, Salum G, Vanderhasselt M, Fraguas R, Benseñor I, Valiengo L, Brunoni A. Precision non-implantable neuromodulation therapies: a perspective for the depressed brain. Brazilian Journal Of Psychiatry 2020, 42: 403-419. PMID: 32187319, PMCID: PMC7430385, DOI: 10.1590/1516-4446-2019-0741.Peer-Reviewed Original ResearchMeSH KeywordsBrainDeep Brain StimulationDepressionDepressive Disorder, MajorElectroconvulsive TherapyHumansTranscranial Direct Current StimulationTranscranial Magnetic StimulationTreatment OutcomeConceptsMajor depressive disorderSide effectsCurrent first-line treatmentMultiple medication trialsMagnetic seizure therapyFirst-line treatmentCognitive side effectsTranscranial direct current stimulationTranscranial magnetic stimulationDirect current stimulationCognitive behavioral therapyCost-effectiveness analysisClinical respondersSeizure therapyElectroconvulsive therapyMedication trialsPathophysiological mechanismsClinical trialsDepressed patientsDepressive disorderDepressed brainMagnetic stimulationNeuromodulation techniquesCurrent stimulationTherapy