2020
Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders
Barron DS, Gao S, Dadashkarimi J, Greene AS, Spann MN, Noble S, Lake EMR, Krystal JH, Constable RT, Scheinost D. Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders. Cerebral Cortex 2020, 31: 2523-2533. PMID: 33345271, PMCID: PMC8023861, DOI: 10.1093/cercor/bhaa371.Peer-Reviewed Original ResearchConceptsMacroscale brain networksIndividual differencesBrain networksMemory deficitsFunctional connectivityAttention deficit hyper-activity disorderTask-based functional MRI dataLong-term memoryWhole-brain functional connectivityDiagnostic groupsWhole-brain patternsDefault mode networkFunctional MRI dataHuman Connectome ProjectPsychiatric disordersMemory constructsMemory performanceTransdiagnostic sampleBrain correlatesMode networkFunctional connectomeConnectome ProjectLimbic networkHealthy participantsMemoryFunctional connectivity predicts changes in attention observed across minutes, days, and months
Rosenberg MD, Scheinost D, Greene AS, Avery EW, Kwon YH, Finn ES, Ramani R, Qiu M, Constable RT, Chun MM. Functional connectivity predicts changes in attention observed across minutes, days, and months. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 3797-3807. PMID: 32019892, PMCID: PMC7035597, DOI: 10.1073/pnas.1912226117.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelsAttentional stateSustained attentionIndividual differencesSustained attention functionFunctional connectivity signaturesFunctional brain connectivityFunctional connectivity patternsAttention functionConnectivity signaturesFunctional connectivityBrain connectivityConnectivity patternsAttentionSingle personSame patternIndividualsConnectivityIndependent studiesRecent workState changesPersonsPeopleDifferencesAbility
2019
There is no single functional atlas even for a single individual: Functional parcel definitions change with task
Salehi M, Greene AS, Karbasi A, Shen X, Scheinost D, Constable RT. There is no single functional atlas even for a single individual: Functional parcel definitions change with task. NeuroImage 2019, 208: 116366. PMID: 31740342, DOI: 10.1016/j.neuroimage.2019.116366.Peer-Reviewed Original ResearchCombining multiple connectomes improves predictive modeling of phenotypic measures
Gao S, Greene AS, Constable RT, Scheinost D. Combining multiple connectomes improves predictive modeling of phenotypic measures. NeuroImage 2019, 201: 116038. PMID: 31336188, PMCID: PMC6765422, DOI: 10.1016/j.neuroimage.2019.116038.Peer-Reviewed Original ResearchConceptsMultiple connectomesLarge open-source datasetOpen-source datasetNovel prediction frameworkPredictive modelingSingle predictive modelPredictive modelArt algorithmsPrediction frameworkMultiple tasksPredictive model approachPrincipled waySpecific algorithmsFunctional connectivity matricesConnectivity matrixDifferent tasksPrediction performanceConnectome-based predictive modelingHuman Connectome ProjectTaskSuperior performanceAlgorithmComplementary informationNaïve extensionsConnectome Project
2018
Task-induced brain state manipulation improves prediction of individual traits
Greene AS, Gao S, Scheinost D, Constable RT. Task-induced brain state manipulation improves prediction of individual traits. Nature Communications 2018, 9: 2807. PMID: 30022026, PMCID: PMC6052101, DOI: 10.1038/s41467-018-04920-3.Peer-Reviewed Original ResearchConceptsBrain statesIndividual differencesBrain-behavior relationshipsFluid intelligence scoresTask-based functional connectivity analysisResting-state fMRI dataBrain functional organizationFunctional connectivity analysisCognitive tasksFluid intelligenceIntelligence scoresFunctional connectivityFMRI dataConnectivity analysisHuman behaviorIndividual traitsTaskCertain tasksFunctional organizationOutperform modelsSuch relationshipsCognitionState manipulationIntelligenceVariance