2024
Pilot study of a novel, alternative subdermal scapular insertion site for the etonogestrel contraceptive implant
Clure C, Sheeder J, Lazorwitz A. Pilot study of a novel, alternative subdermal scapular insertion site for the etonogestrel contraceptive implant. Contraception 2024, 135: 110442. PMID: 38552822, DOI: 10.1016/j.contraception.2024.110442.Peer-Reviewed Original ResearchEtonogestrel contraceptive implantContraceptive implantsMedian body mass indexMedian pain scoreBody mass indexTime pointsBleeding side effectsEtonogestrel implantImplant placementReproductive-age femalesENG implantSite painPain scoresMedian ageInsertion siteEtonogestrelMass indexPilot studyPatient populationInferior edgeSide effectsPharmacokineticsImplantationWeeksSerum
2023
An exploratory study on the possible association of serum etonogestrel concentrations with mood concerns and symptoms among contraceptive implant users
Diamond B, Sheeder J, Lazorwitz A. An exploratory study on the possible association of serum etonogestrel concentrations with mood concerns and symptoms among contraceptive implant users. Contraception 2023, 129: 110298. PMID: 37802462, PMCID: PMC10842501, DOI: 10.1016/j.contraception.2023.110298.Peer-Reviewed Original ResearchConceptsMood-related side effectsContraceptive implant usersENG implant usersInter-individual variabilitySide effectsImplant usersEtonogestrel contraceptive implant usersMood changesWide inter-individual variabilitySerum etonogestrel concentrationsPHQ-9 scoresSerum drug levelsLiquid chromatography-mass spectrometry assaySubset of participantsEtonogestrel concentrationsPrimary outcomePharmacokinetic variabilityMood concernsBaseline questionnairePHQ-9Blood drawDrug levelsMood symptomsImplant usePossible association
2022
P077Pilot study on a novel, alternative subdermal scapular insertion site for the etonogestrel contraceptive implant
Clure C, Sheeder J, Lazorwitz A. P077Pilot study on a novel, alternative subdermal scapular insertion site for the etonogestrel contraceptive implant. Contraception 2022, 116: 91. DOI: 10.1016/j.contraception.2022.09.101.Peer-Reviewed Original ResearchEtonogestrel contraceptive implantContraceptive implantsENG implantENG levelsSide effectsMedian pain scoreTime pointsReproductive-aged womenScapular insertionPain scoresSite painMedian ageMedian BMIImplant useInferior edgeInsertion siteWeek twoYears of useFirst weekPilot studyImplant usersPharmacokineticsImplantsFirst yearWeeksDiscontinuation of hormonal contraception due to changes in mood and decreases in sexual desire: the role of adverse childhood experiences
Novick AM, Johnson RL, Lazorwitz A, Belyavskaya A, Berkowitz L, Norton A, Sammel MD, Epperson CN. Discontinuation of hormonal contraception due to changes in mood and decreases in sexual desire: the role of adverse childhood experiences. The European Journal Of Contraception & Reproductive Health Care 2022, 27: 212-220. PMID: 35133231, PMCID: PMC9133050, DOI: 10.1080/13625187.2022.2030702.Peer-Reviewed Original Research
2021
Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraception
Lazorwitz A, Aquilante C, Shortt J, Sheeder J, Teal S, Gignoux C. Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraception. Clinical And Translational Science 2021, 14: 1713-1718. PMID: 33650294, PMCID: PMC8504805, DOI: 10.1111/cts.13014.Peer-Reviewed Original ResearchConceptsSelf-reported race/ethnicityHispanic/Latina ethnicityRace/ethnicityContraceptive implant usersSerum etonogestrel concentrationsEtonogestrel concentrationsLatina ethnicitySide effectsBlack/African American raceImplant usersSelf-reported black raceReproductive-aged womenNon-Hispanic raceMultivariable logistic regressionAfrican American racePharmacodynamics/pharmacokineticsHormonal contraceptionPharmacodynamic outcomesBlack race
2019
Relationship Between Etonogestrel Concentrations and Bleeding Patterns in Contraceptive Implant Users.
Lazorwitz A, Aquilante C, Dindinger E, Harrison M, Sheeder J, Teal S. Relationship Between Etonogestrel Concentrations and Bleeding Patterns in Contraceptive Implant Users. Obstetrics And Gynecology 2019, 134: 807-813. PMID: 31503152, PMCID: PMC6768730, DOI: 10.1097/aog.0000000000003452.Peer-Reviewed Original ResearchConceptsSerum etonogestrel concentrationsContraceptive implant usersEtonogestrel concentrationsOral contraceptive pillsRelated side effectsAbnormal bleedingSide effectsBleeding patternsContraceptive pillsContraceptive implantsBothersome bleedingImplant usersProspective cross-sectional studyReproductive-aged womenMultivariable logistic regressionHormonal contraceptive methodsCross-sectional studyDiscontinuation ratesEtonogestrel implantsPatient satisfactionPill prescriptionMedical recordsBleedingContraceptive methodsImplant use