2022
Discontinuation of hormonal contraception due to changes in mood and decreases in sexual desire: the role of adverse childhood experiences
Novick AM, Johnson RL, Lazorwitz A, Belyavskaya A, Berkowitz L, Norton A, Sammel MD, Epperson CN. Discontinuation of hormonal contraception due to changes in mood and decreases in sexual desire: the role of adverse childhood experiences. The European Journal Of Contraception & Reproductive Health Care 2022, 27: 212-220. PMID: 35133231, PMCID: PMC9133050, DOI: 10.1080/13625187.2022.2030702.Peer-Reviewed Original Research
2021
Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraception
Lazorwitz A, Aquilante C, Shortt J, Sheeder J, Teal S, Gignoux C. Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraception. Clinical And Translational Science 2021, 14: 1713-1718. PMID: 33650294, PMCID: PMC8504805, DOI: 10.1111/cts.13014.Peer-Reviewed Original ResearchConceptsSelf-reported race/ethnicityHispanic/Latina ethnicityRace/ethnicityContraceptive implant usersSerum etonogestrel concentrationsEtonogestrel concentrationsLatina ethnicitySide effectsBlack/African American raceImplant usersSelf-reported black raceReproductive-aged womenNon-Hispanic raceMultivariable logistic regressionAfrican American racePharmacodynamics/pharmacokineticsHormonal contraceptionPharmacodynamic outcomesBlack race
2019
Pre- and post-operative counseling for women on hormonal contraceptives receiving sugammadex at an academic hospital
Lazorwitz A, Dindinger E, Aguirre N, Sheeder J. Pre- and post-operative counseling for women on hormonal contraceptives receiving sugammadex at an academic hospital. Journal Of Anesthesia 2019, 34: 294-297. PMID: 31865457, PMCID: PMC8496978, DOI: 10.1007/s00540-019-02725-2.Peer-Reviewed Original ResearchConceptsHormonal contraceptionDrug-drug interactionsUnintended pregnancyPost-operative counselingRetrospective chart reviewChart reviewRisk patientsHormonal contraceptivesColorado HospitalAcademic hospitalFDA labelContraceptive methodsSugammadexContraceptionPatientsWomenUnnecessary riskPregnancyHospitalCounselingExposureMedicationsContraceptivesProgestinsEstrogenInfluence of Genetic Variants on Steady-State Etonogestrel Concentrations Among Contraceptive Implant Users.
Lazorwitz A, Aquilante C, Oreschak K, Sheeder J, Guiahi M, Teal S. Influence of Genetic Variants on Steady-State Etonogestrel Concentrations Among Contraceptive Implant Users. Obstetrics And Gynecology 2019, 133: 783-794. PMID: 30870275, PMCID: PMC6448146, DOI: 10.1097/aog.0000000000003189.Peer-Reviewed Original ResearchConceptsSerum etonogestrel concentrationsBody mass indexContraceptive implant usersEtonogestrel concentrationsSteroid hormone metabolismImplant useGenetic variantsHepatic enzyme inducersReproductive-age womenImplant usersHormone metabolismPersonalized medicine approachVariant allele frequencyOvulatory suppressionEtonogestrel implantsMass indexHormonal contraceptionConcomitant useWomen's healthPg/Medicine approachParticipant characteristicsSteroid hormonesEnzyme inducersPharmacogenomic investigations