2019
Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study
Makanga PT, Sacoor C, Schuurman N, Lee T, Vilanculo FC, Munguambe K, Boene H, Ukah UV, Vidler M, Magee LA, Sevene E, von Dadelszen P, Firoz T, Macete E, Vala A, Amose F, Pires R, Nhamirre Z, Macamo M, Chiaú R, Matavele A, Nhancolo A, Cutana S, Mandlate E, Macuacua S, Bique C, Mocumbi S, Gonçálves E, Maculuve S, Biz A, Mulungo D, Augusto O, Filimone P, Nobela V, Tchavana C, Nkumbula C, Bone J, Dunsmuir D, Drebit S, Kariya C, Kinshella M, Li J, Lui M, Payne B, Khowaja A, Sawchuck D, Sharma S, Tu D, Ukah U. Place-specific factors associated with adverse maternal and perinatal outcomes in Southern Mozambique: a retrospective cohort study. BMJ Open 2019, 9: e024042. PMID: 30782892, PMCID: PMC6367983, DOI: 10.1136/bmjopen-2018-024042.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, SpontaneousAdultCohort StudiesFamilyFemaleFloodsGeographyHealth Services AccessibilityHumansInfant, NewbornLeast-Squares AnalysisLive BirthMaternal AgeMaternal MortalityMozambiqueParityPerinatal MortalityPregnancyPregnancy OutcomeRegression AnalysisRetrospective StudiesSocial SupportStillbirthToilet FacilitiesYoung AdultConceptsRetrospective cohort studyPerinatal outcomesCohort studyMaternal healthReproductive-age womenCommunity health workersCommunity-level interventionsNeonatal outcomesAdverse outcomesAge womenReproductive ageHealth workersDelphi consensusAverage ageTargeted interventionsSocial determinantsSignificant geographic variabilityLevel interventionsMultisectoral collaborationWomenBaseline phaseHousehold censusOutcomesPregnancyFamily support
2018
Validation of the WHO Disability Assessment Schedule (WHODAS 2.0) 12‐item tool against the 36‐item version for measuring functioning and disability associated with pregnancy and history of severe maternal morbidity
Silveira C, Souza RT, Costa ML, Parpinelli MA, Pacagnella RC, Ferreira EC, Mayrink J, Guida JP, Sousa MH, Say L, Chou D, Filippi V, Barreix M, Barbour K, Firoz T, von Dadelszen P, Cecatti JG, Andreucci C, Andreucci C, Angelini C, Angelini C, Ferraz J, Ferraz J, Zanardi D, Zanardi D, Camargo R, Cottler S, Fawole O, Gadama L, Ghérissi A, Gyte G, Hindin M, Jayathilaka A, Kalamar A, Kone Y, Kostanjsek N, Lange I, Magee L, Mathur A, McCaw‐Binns A, Morgan M, Munjanja S, Gichuhi G, Petzold M, Sullivan E, Taulo F, Tunçalp Ö, Vanderkruik R. Validation of the WHO Disability Assessment Schedule (WHODAS 2.0) 12‐item tool against the 36‐item version for measuring functioning and disability associated with pregnancy and history of severe maternal morbidity. International Journal Of Gynecology & Obstetrics 2018, 141: 39-47. PMID: 29851113, PMCID: PMC6001571, DOI: 10.1002/ijgo.12465.Peer-Reviewed Original ResearchConceptsSevere maternal morbidityMaternal morbidityWHO Disability Assessment ScheduleTotal scoreRetrospective cohort studyDisability Assessment ScheduleInternal consistencyWHODAS-12Cohort studyPostpartum womenYear postpartumTertiary facilityAssessment ScheduleGood internal consistencySecondary analysisMorbidityMean differenceWomenConfirmatory factor analysisInstrument agreementLong-term repercussionsCronbach's alphaPregnancyAlpha coefficientScoresA framework for healthcare interventions to address maternal morbidity
Firoz T, McCaw‐Binns A, Filippi V, Magee LA, Costa ML, Cecatti JG, Barreix M, Adanu R, Chou D, Say L, Barbour K, Cottler S, Fawole O, Gadama L, Ghérissi A, Gyte G, Hindin M, Jayathilaka A, Kalamar A, Kone Y, Kostanjsek N, Lange I, Mathur A, Morgan M, Munjanja S, Gichuhi G, Petzold M, Sullivan E, Taulo F, Tunçalp Ö, Vanderkruik R, von Dadelszen P. A framework for healthcare interventions to address maternal morbidity. International Journal Of Gynecology & Obstetrics 2018, 141: 61-68. PMID: 29851114, PMCID: PMC6001624, DOI: 10.1002/ijgo.12469.Peer-Reviewed Original ResearchConceptsMaternal healthMaternal morbidityChronic conditionsNoncommunicable diseasesEmergency obstetric careMaternal health servicesIntegrated health programsLong-term healthNCD programsMaternal deathsObstetric carePregnant womenWomen's healthMorbidityEarly interventionHealth servicesHealth programsHealth systemHealthcare interventionsHealth agendaFuture healthRelated interventionsWomenPregnancyInterventionHypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy
Butalia S, Audibert F, Côté AM, Firoz T, Logan AG, Magee LA, Mundle W, Rey E, Rabi DM, Daskalopoulou SS, Nerenberg KA, Canada H. Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy. Canadian Journal Of Cardiology 2018, 34: 526-531. PMID: 29731014, DOI: 10.1016/j.cjca.2018.02.021.Peer-Reviewed Original ResearchConceptsManagement of hypertensionAntihypertensive therapySevere hypertensionBlood pressure targetsNewborn adverse outcomesManagement of womenTreatment of hypertensionGynaecologists of CanadaSociety of ObstetriciansAntihypertensive medicationsNonsevere hypertensionPressure targetsNewborn complicationsAdverse outcomesCanadian recommendationsHypertensionPregnancyCanada guidelinesTherapyGuidelinesSpecific evidenceManagementMedicationsComplicationsObstetricians
2017
Seasonal variation in geographical access to maternal health services in regions of southern Mozambique
Makanga PT, Schuurman N, Sacoor C, Boene HE, Vilanculo F, Vidler M, Magee L, von Dadelszen P, Sevene E, Munguambe K, Firoz T. Seasonal variation in geographical access to maternal health services in regions of southern Mozambique. International Journal Of Health Geographics 2017, 16: 1. PMID: 28086893, PMCID: PMC5237329, DOI: 10.1186/s12942-016-0074-4.Peer-Reviewed Original ResearchConceptsMaternal health servicesLife-saving careHealth facilitiesHealth servicesPregnant womenPrimary care centersMaternal careGeographical accessNearest health facilityHealth service planningPopulation of womenMinistry of HealthResultsForty-sixTertiary facilityReproductive ageCare centerHealth centersWomen populationFacility assessmentsSecondary facilitiesCareWomenService planningHousehold censusDeterminants of accessIncidence of myocardial infarction in pregnancy: a systematic review and meta-analysis of population-based studies
Gibson P, Narous M, Firoz T, Chou D, Barreix M, Say L, James M, Group O. Incidence of myocardial infarction in pregnancy: a systematic review and meta-analysis of population-based studies. European Heart Journal - Quality Of Care And Clinical Outcomes 2017, 3: 198-207. PMID: 28838086, PMCID: PMC5862024, DOI: 10.1093/ehjqcco/qcw060.Peer-Reviewed Original ResearchConceptsPregnancy-associated myocardial infarctionCase fatality rateMyocardial infarctionMaternal mortalitySystematic reviewIndirect maternal deathsMaternal myocardial infarctionPooled incidence estimatesCardiovascular risk factorsPopulation-based cohortPopulation-based studyCase-control studyHigh rateMaternal incidencePooled incidenceMaternal deathsCommon etiologyMaternal ageRisk factorsIncidence estimatesCardiac diseaseDate restrictionsMortality rateFatality rateElectronic databases
2016
Community perspectives on the determinants of maternal health in rural southern Mozambique: a qualitative study
Firoz T, Vidler M, Makanga PT, Boene H, Chiaú R, Sevene E, Magee LA, von Dadelszen P, Munguambe K, the CLIP Working Group. Community perspectives on the determinants of maternal health in rural southern Mozambique: a qualitative study. Reproductive Health 2016, 13: 112. PMID: 27719679, PMCID: PMC5056498, DOI: 10.1186/s12978-016-0217-x.Peer-Reviewed Original ResearchConceptsSocio-cultural determinantsRural southern MozambiqueQualitative studyIntimate partner violenceKey community groupsExploratory qualitative studyFocus group discussionsGender relationsMaternal healthDeterminants of healthCivil warPartner violenceCommunity representativesLocal contextCommunity leadersCommunity perspectiveCommunity groupsMaternal health programsLocal unemploymentCommunity perceptionsLocal historyCultural determinantsSocial relationshipsAdministrative postsHealth sectorBarriers and facilitators to health care seeking behaviours in pregnancy in rural communities of southern Mozambique
Munguambe K, Boene H, Vidler M, Bique C, Sawchuck D, Firoz T, Makanga PT, Qureshi R, Macete E, Menéndez C, von Dadelszen P, Sevene E. Barriers and facilitators to health care seeking behaviours in pregnancy in rural communities of southern Mozambique. Reproductive Health 2016, 13: 31. PMID: 27356968, PMCID: PMC4943506, DOI: 10.1186/s12978-016-0141-0.Peer-Reviewed Original ResearchConceptsHealth care providersCommunity health workersHealth facilitiesCare providersPregnant womenAntenatal careReproductive ageHealth workersHealth carePrimary health care providersTimely appropriate careLower abdominal painFlu-like symptomsTraditional healersTraditional birth attendantsWomen's health careHealth care servicesCommunity-based health care providersAntenatal cardsAbdominal painAntenatal recordsPrompt referralBirth preparednessLack of transportAntenatal periodConstructing maternal morbidity – towards a standard tool to measure and monitor maternal health beyond mortality
Chou D, Tunçalp Ö, Firoz T, Barreix M, Filippi V, von Dadelszen P, van den Broek N, Cecatti JG, Say L, on behalf of the Maternal Morbidity Working Group. Constructing maternal morbidity – towards a standard tool to measure and monitor maternal health beyond mortality. BMC Pregnancy And Childbirth 2016, 16: 45. PMID: 26935070, PMCID: PMC4774187, DOI: 10.1186/s12884-015-0789-4.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHumansMaternal HealthMorbidityPregnancyPregnancy ComplicationsTerminology as TopicConceptsMaternal morbidityUniversal health coverageRelated Health ProblemsMorbidity categoriesMaternal historyMaternal healthDisability componentMedical conditionsMorbidityInternational ClassificationHealth problemsHealth conditionsHealth coverageExpert meetingStandard identification criteriaAssessment toolWomenGoal planningLiterature reviewPregnancyReviewSymptomsMortalityPrevalenceChildbirthChoice of Imaging Studies in Acutely Ill Pregnant Women
Firoz T, Miller MA, Bourjeily G. Choice of Imaging Studies in Acutely Ill Pregnant Women. CHEST Journal 2016, 149: 290-291. PMID: 26757297, DOI: 10.1016/j.chest.2015.10.055.Peer-Reviewed Original Research
2015
In Response
Magee LA, Pels A, Helewa M, Rey E, von Dadelszen P, Bujold E, Côté AM, Douglas MJ, Eastabrook G, Firoz T, Gibson P, Gruslin A, Hutcheon J, Koren G, Lange I, Leduc L, Logan AG, MacDonell KL, Moutquin JM, Sebbag I, Audibert F. In Response. Journal Of Obstetrics And Gynaecology Canada 2015, 37: 775-776. PMID: 26605445, DOI: 10.1016/s1701-2163(15)30146-8.Peer-Reviewed Original Research
2014
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review
Firoz T, Magee L, MacDonell K, Payne B, Gordon R, Vidler M, von Dadelszen P, Group T. Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review. BJOG An International Journal Of Obstetrics & Gynaecology 2014, 121: 1210-1218. PMID: 24832366, PMCID: PMC4282072, DOI: 10.1111/1471-0528.12737.Peer-Reviewed Original ResearchConceptsOral antihypertensive agentsSevere hypertensionAntihypertensive agentsRelative riskOral antihypertensive therapySublingual nifedipine capsulesBlood pressure reductionRisk of strokePregnancy/postpartumResource-constrained settingsAntihypertensive therapyExperienced hypotensionOral labetalolOral nifedipineParenteral hydralazineFetal outcomesOral agentsPostpartum hypertensionDiastolic BPSystolic BPDATA COLLECTIONNifedipine capsulesTarget BPCochrane LibraryPostpartum womenMagnesium Sulphate for the Management of Preeclampsia and Eclampsia in Low and Middle Income Countries: A Systematic Review of Tested Dosing Regimens
Gordon R, Magee LA, Payne B, Firoz T, Sawchuck D, Tu D, Vidler M, de Silva D, von Dadelszen P. Magnesium Sulphate for the Management of Preeclampsia and Eclampsia in Low and Middle Income Countries: A Systematic Review of Tested Dosing Regimens. Journal Of Obstetrics And Gynaecology Canada 2014, 36: 154-163. PMID: 24518915, DOI: 10.1016/s1701-2163(15)30662-9.Peer-Reviewed Original ResearchConceptsManagement of preeclampsiaLoading doseMiddle-income countriesCare facilitiesMgSO4 loading doseRate of eclampsiaRelevant English language publicationsDuration of treatmentMagnesium sulfateUse of MgSO4Income countriesEnglish-language publicationsMaternal safetyMaintenance dosingDosing regimensEclampsiaHospital settingEclampsia treatmentMinimum effective dosagePreeclampsiaSystematic reviewMgSO4 loadingRegimensEffective dosageLanguage publications
2013
Pharmacotherapy for Preeclampsia in Low and Middle Income Countries: An Analysis of Essential Medicines Lists
Lalani S, Firoz T, Magee LA, Sawchuck D, Payne B, Gordon R, Vidler M, von Dadelszen P. Pharmacotherapy for Preeclampsia in Low and Middle Income Countries: An Analysis of Essential Medicines Lists. Journal Of Obstetrics And Gynaecology Canada 2013, 35: 215-223. PMID: 23470109, DOI: 10.1016/s1701-2163(15)30993-2.Peer-Reviewed Original ResearchConceptsEssential Medicines ListAntihypertensive therapyMiddle-income countriesMedicines ListOral antihypertensive therapyParenteral antihypertensive therapyNational essential medicines listsEclampsia/preeclampsiaPrevalence of drugIncome countriesWorld Health OrganizationOral furosemidePreeclampsia complicationsLabor inductionPreterm birthPulmonary edemaParenteral dexamethasoneSodium nitroprussideCalcium gluconatePreeclampsiaTherapyHealth OrganizationMagnesium sulfateComprehensive managementPharmacotherapy
2012
Preeclampsia in Low and Middle Income Countries—Health Services Lessons Learned From the PRE-EMPT (PRE-Eclampsia–Eclampsia Monitoring, Prevention & Treatment) Project
von Dadelszen P, Firoz T, Donnay F, Gordon R, Hofmeyr G, Lalani S, Payne BA, Roberts JM, Teela KC, Vidler M, Sawchuck D, Magee LA. Preeclampsia in Low and Middle Income Countries—Health Services Lessons Learned From the PRE-EMPT (PRE-Eclampsia–Eclampsia Monitoring, Prevention & Treatment) Project. Journal Of Obstetrics And Gynaecology Canada 2012, 34: 917-926. PMID: 23067947, DOI: 10.1016/s1701-2163(16)35405-6.Peer-Reviewed Original ResearchConceptsHypertensive disordersAdverse eventsMiddle-income countriesMillennium Development Goal 5Impact of preeclampsiaMagnesium sulfate therapyIncome countriesParticular preeclampsiaPreeclampsia preventionSulfate therapyRisk stratificationHealth burdenPreeclampsiaHealth servicesMobile healthGoal 5WomenDisordersPriority focusLesser extentComplicationsPregnancyTherapyPreventionThe PIERS Experience: Research or Quality Improvement?
Firoz T, Magee LA, Payne BA, Menzies JM, von Dadelszen P, Group F. The PIERS Experience: Research or Quality Improvement? Journal Of Obstetrics And Gynaecology Canada 2012, 34: 379-381. PMID: 22472340, DOI: 10.1016/s1701-2163(16)35221-5.Peer-Reviewed Original Research
2011
Pre-eclampsia in low and middle income countries
Firoz T, Sanghvi H, Merialdi M, von Dadelszen P. Pre-eclampsia in low and middle income countries. Best Practice & Research Clinical Obstetrics & Gynaecology 2011, 25: 537-548. PMID: 21592865, DOI: 10.1016/j.bpobgyn.2011.04.002.Peer-Reviewed Original ResearchConceptsHealth care workersCare workersCommunity health care workersTreatment of eclampsiaDrug of choiceHealth care forcePerinatal morbidityBlood pressureMiddle-income countriesPre-eclampsiaExact prevalencePrinciples of careMaternal mortalityPregnant womenRelated deathsHealth care worker shortageTimely careEclampsiaPrevention strategiesLMICsLack of trainingMagnesium sulfateWomenIncome countriesMortalityPostpartum evaluation and long term implications
Firoz T, Melnik T. Postpartum evaluation and long term implications. Best Practice & Research Clinical Obstetrics & Gynaecology 2011, 25: 549-561. PMID: 21536498, DOI: 10.1016/j.bpobgyn.2011.03.003.Peer-Reviewed Original ResearchConceptsCardiovascular diseaseEarly-onset pre-eclampsiaPre-existing metabolic abnormalitiesTraditional cardiovascular risk factorsCardiovascular risk factorsPremature cardiovascular diseaseIschemic heart diseaseManagement of hypertensionHeart-healthy lifestyleLong-term implicationsPostpartum evaluationRenal diseaseMetabolic abnormalitiesPre-eclampsiaNext pregnancyWeeks postpartumHeart diseaseMonths postpartumPostpartum periodRisk factorsSecondary causesHigh riskHypertensionCare needsDisease pathophysiology