Modulation of systolic and diastolic function by endothelin‐1: relation to coronary flow
OFFSTAD J, TØNNESSEN T, KIRKEBØEN KA, ILEBEKK A, DOWNING SE. Modulation of systolic and diastolic function by endothelin‐1: relation to coronary flow. Acta Physiologica 1995, 154: 103-111. PMID: 7572206, DOI: 10.1111/j.1748-1716.1995.tb09892.x.Peer-Reviewed Original ResearchConceptsCoronary flowConstant perfusion pressureDiastolic stiffnessET-1Constant coronary flowDiastolic functionVentricular end-diastolic pressureVentricular systolic pressureEnd-diastolic pressureLeft ventricular functionEffects of endothelinPositive inotropic effectHaemodynamic alterationsSystolic functionPerfusion pressureSystolic pressureVentricular functionDiastolic pressureInotropic effectEndothelin-1Cardiac contractilityMmHg sCPP groupRat heartMmHg