Mitochondrial network reorganization and transient expansion during oligodendrocyte generation
Bame X, Hill R. Mitochondrial network reorganization and transient expansion during oligodendrocyte generation. Nature Communications 2024, 15: 6979. PMID: 39143079, PMCID: PMC11324877, DOI: 10.1038/s41467-024-51016-2.Peer-Reviewed Original ResearchConceptsDecreased mitochondrial sizeLoss of mitochondriaMitochondrial motilityMitochondrial dynamicsCellular checkpointsMitochondrial distributionMitochondrial sizeMitochondrial contentOligodendrocyte precursor cellsSubcellular partitioningDistal processesMotilityOligodendrocyte generationOligodendrocyte processesLocal microenvironmentPrecursor cellsExtensive expansionMitochondriaOligodendrocyte lineageTransient expansionLineagesOligodendrocytesAging brainMyelinating oligodendrocytesMorphometrics