Surgical Monotherapy Versus Surgery Plus Adjuvant Radiotherapy in High‐Risk Cutaneous Squamous Cell Carcinoma: A Systematic Review of Outcomes
Jambusaria‐PAHLAJANI A, MILLER CJ, QUON H, SMITH N, KLEIN RQ, SCHMULTS CD. Surgical Monotherapy Versus Surgery Plus Adjuvant Radiotherapy in High‐Risk Cutaneous Squamous Cell Carcinoma: A Systematic Review of Outcomes. Dermatologic Surgery 2009, 35: 574-584. PMID: 19415791, DOI: 10.1111/j.1524-4725.2009.01095.x.Peer-Reviewed Original ResearchConceptsHigh-risk SCCAdjuvant radiotherapyClear surgical marginsDisease-specific deathPerineural invasionLocal recurrenceDistant metastasisSurgical marginsHigh-risk cutaneous squamous cell carcinomaCases of PNICutaneous squamous cell carcinomaHigh-risk featuresSurgical margin statusHigh cure ratesSquamous cell carcinomaOutcomes of interestNerve involvementMargin statusRegional metastasesCutaneous SCCWorse prognosisSCC casesSquamous cellsCell carcinomaCure rate