2024
Trust under development: The Italian validation of the Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) for adolescents
Milesi A, Liotti M, Locati F, De Carli P, Speranza A, Campbell C, Fonagy P, Lingiardi V, Parolin L. Trust under development: The Italian validation of the Epistemic Trust, Mistrust, and Credulity Questionnaire (ETMCQ) for adolescents. PLOS ONE 2024, 19: e0307229. PMID: 39186540, PMCID: PMC11346731, DOI: 10.1371/journal.pone.0307229.Peer-Reviewed Original ResearchConceptsSelf-report instrumentEpistemic trustContext of personality disordersConcept of epistemic trustDevelopment of mental disordersPersonality disorderEmotion dysregulationMeasure mentalizingMental disordersPsychological functioningItalian validationMental healthPsychopathologyAdolescent populationInterpersonal trustAdolescentsDisordersResearch contextEmpirical validationHigh schoolItalian adult populationAdult populationMentalQuestionnaireValidityHuman adolescent brain similarity development is different for paralimbic versus neocortical zones
Dorfschmidt L, Váša F, White S, Romero-García R, Kitzbichler M, Alexander-Bloch A, Cieslak M, Mehta K, Satterthwaite T, Consortium T, Bethlehem R, Seidlitz J, Vértes P, Bullmore E, Bullmore E, Dolan R, Goodyer I, Fonagy P, Jones P, Moutoussis M, Hauser T, Neufeld S, Romero-Garcia R, St Clair M, Vértes P, Whitaker K, Inkster B, Prabhu G, Ooi C, Toseeb U, Widmer B, Bhatti J, Villis L, Alrumaithi A, Birt S, Bowler A, Cleridou K, Dadabhoy H, Davies E, Firkins A, Granville S, Harding E, Hopkins A, Isaacs D, King J, Kokorikou D, Maurice C, McIntosh C, Memarzia J, Mills H, O’Donnell C, Pantaleone S, Scott J, Kiddle B, Polek E, Fearon P, Suckling J, van Harmelen A, Kievit R, Chamberlain S, Bethlehem R. Human adolescent brain similarity development is different for paralimbic versus neocortical zones. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2314074121. PMID: 39121162, PMCID: PMC11331068, DOI: 10.1073/pnas.2314074121.Peer-Reviewed Original ResearchConceptsMorphometric similarity networksFunctional connectivityNeocortical areasCortical areasFunctional MRI scansCourse of adolescenceAccelerated longitudinal designMagnetic resonance imagingStructure-function couplingCingulate cortexParalimbic areasInteroceptive functionAssociated with increased strengthIncreased hubnessFMRI networksStructural scansLongitudinal designCortical thinningDevelopment of human brainAdolescent developmentMorphometric similarityHealthy adolescentsAssociated with reduced strengthHuman brainCortexWHO treatment guideline for mental disorders
Leichsenring F, Abbass A, Fonagy P, Levy K, Lilliengren P, Luyten P, Midgley N, Milrod B, Steinert C. WHO treatment guideline for mental disorders. The Lancet Psychiatry 2024, 11: 676-677. PMID: 39067469, DOI: 10.1016/s2215-0366(24)00169-x.Peer-Reviewed Original ResearchExamination of a case of “treatment failure” in long-term psychoanalytic psychotherapy for treatment-resistant depression
Willemsen J, Rost F, Hustinx M, Fonagy P, Taylor D. Examination of a case of “treatment failure” in long-term psychoanalytic psychotherapy for treatment-resistant depression. The International Journal Of Psychoanalysis 2024, 105: 475-495. PMID: 39230487, DOI: 10.1080/00207578.2024.2352827.Peer-Reviewed Original ResearchConceptsTreatment-resistant depressionPsychoanalytic psychotherapyLong-term psychoanalytic psychotherapyLevels of depressionNegative therapeutic reactionExperiences of abandonmentPatients' levels of depressionStructured Clinical AssessmentPost-treatment outcomesTherapeutic relationshipPatterns of repetitionTherapy processTherapeutic reactionDepressionPsychic conflictPsychotherapyInternal worldInner worldClinical assessmentRandomized controlled trialsLack of symbolismDestructive patternsResearch contextInterpretive stanceTherapistsBrief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics
James K, Lisk S, Payne-Cook C, Farishta Z, Farrelly M, Sheikh A, Slusarczyk M, Byford S, Day C, Deighton J, Evans C, Fonagy P, Saunders D, Sclare I, Shearer J, Stallard P, Weaver T, Yarrum J, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST trial), a school-based cluster randomised controlled trial of the DISCOVER workshop for 16–18-year-olds: recruitment and baseline characteristics. Trials 2024, 25: 302. PMID: 38702825, PMCID: PMC11069277, DOI: 10.1186/s13063-024-08116-7.Peer-Reviewed Original ResearchConceptsSchool-based cluster randomised controlled trialWarwick-Edinburgh Mental Wellbeing ScaleCluster randomised controlled trialRandomised controlled trialsSchools TrialEducational workshopsMental Wellbeing ScaleControlled trialsOutcome data collectionSymptoms of depressionEthnic minority groupsSecondary schoolsReduce stigmaBaseline characteristicsPost-randomisationWellbeing ScaleSelf-referralSelf-referredLower wellbeingStudentsDistressed studentsEthnically diverse sampleSchoolWorkshop programmeGeneral wellbeingImplementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya—individually randomised superiority trial
Fonagy P, Chammay R, Ngunu C, Kumar M, Verdeli L, Allison E, Anani G, Fearon P, Fouad F, Hoare Z, Koyio L, Moore H, Nyandigisi A, Pilling S, Sender H, Skordis J, Evans R, Jaoude G, Madeghe B, Maradian S, O’Donnell C, Simes E, Truscott A, Wambua G, Yator O. Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya—individually randomised superiority trial. Trials 2024, 25: 217. PMID: 38532432, PMCID: PMC10964704, DOI: 10.1186/s13063-024-08039-3.Peer-Reviewed Original ResearchConceptsPostnatal depressionInterpersonal psychotherapyChild developmental outcomesMulti-site randomised controlled trialWomen's mental health needsStandard careEfficacy of interpersonal psychotherapyMaternal postnatal depressionMental health needsMental health concernsMiddle-income countriesRandomised controlled trialsDevelopmental outcomesHigh-income countriesAntenatal servicesChildbearing womenMother-child bondingRandomised superiority trialChildren's developmental progressHealth needsOffspring of womenMaternal depressionCommunity settingsLMIC contextsInterpersonal therapyClinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK
Bennett S, Cross J, Chowdhury K, Ford T, Heyman I, Coughtrey A, Dalrymple E, Byford S, Chorpita B, Fonagy P, Moss-Morris R, Reilly C, Smith J, Stephenson T, Varadkar S, Blackstone J, Quartly H, Hughes T, Lewins A, Moore E, Walji F, Welch A, Whelan E, Zacharia A, D'Oelsnitz A, Shah M, Xu L, Vezyroglou A, Mitchell K, Nizza I, Ganguli P, Shafran R. Clinical effectiveness of the psychological therapy Mental Health Intervention for Children with Epilepsy in addition to usual care compared with assessment-enhanced usual care alone: a multicentre, randomised controlled clinical trial in the UK. The Lancet 2024, 403: 1254-1266. PMID: 38461840, DOI: 10.1016/s0140-6736(23)02791-5.Peer-Reviewed Original ResearchConceptsChronic health conditionsMental health disordersUsual careMental health interventionsMental health difficultiesHealth conditionsHealth disordersHealth interventionsHealth difficultiesProgramme Grants for Applied Research programmeNational Institute for Health Research Programme Grants for Applied Research programmeTreating common mental health conditionsMICE groupPrimary mental health disorderYoung peopleMental health comorbiditiesMonths post-randomisationStudy inclusionMental health conditionsEvidence-based psychological treatmentsMental health treatmentMental health assessmentIntellectual disabilityParent-reported StrengthsParticipants aged 3A short version of the reflective functioning questionnaire: Validation in a greek sample.
Karagiannopoulou E, Milienos F, Desatnik A, Rentzios C, Athanasopoulos V, Fonagy P. A short version of the reflective functioning questionnaire: Validation in a greek sample. PLOS ONE 2024, 19: e0298023. PMID: 38319928, PMCID: PMC10846711, DOI: 10.1371/journal.pone.0298023.Peer-Reviewed Original ResearchConceptsReflective Functioning QuestionnaireBorderline personality disorderPsychological mindednessEpistemic mistrustEmotion regulationReflective functioningEpistemic trustBorderline personality disorder groupAssociated with insecure attachment stylesRobust three-factor structureBorderline personality traitsFactor structure invarianceNon-clinical groupPoor emotion regulationInsecure attachment stylesThree-factor structureMental health symptomsInternal mental statesCut-off scoreSelf-report questionnairesFunction QuestionnaireImpaired mental capacityPersonality disorderInsecure attachmentAttachment classificationsMentalizing psychiatric training
Fonagy P. Mentalizing psychiatric training. Acta Psychiatrica Scandinavica 2024, 149: 173-176. PMID: 38320854, DOI: 10.1111/acps.13662.Peer-Reviewed Original ResearchCommentary: Special Issue on Interpersonal Trust.
Fonagy P, Campbell C, Allison E, Luyten P. Commentary: Special Issue on Interpersonal Trust. Journal Of Personality Disorders 2024, 38: 10-18. PMID: 38324249, DOI: 10.1521/pedi.2024.38.1.10.Peer-Reviewed Original ResearchBayesian Decision-Making Under Uncertainty in Borderline Personality Disorder.
Manavalan M, Song X, Nolte T, Fonagy P, Montague P, Vilares I. Bayesian Decision-Making Under Uncertainty in Borderline Personality Disorder. Journal Of Personality Disorders 2024, 38: 53-74. PMID: 38324252, DOI: 10.1521/pedi.2024.38.1.53.Peer-Reviewed Original ResearchConceptsBorderline personality disorder patientsBorderline personality disorderPersonality disorderCharacteristics of borderline personality disorderSensorimotor tasksDomain-generalGeneral deficitPotential deficitsHealthy controlsDeficitsOptimal decision-makingDisordersTaskLowered levelsSensorimotorBorderlineCurrent informationDecision-makingBeliefsPerceptionEnhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial
Williams A, Cleare S, Borschmann R, Tench C, Gross J, Hollis C, Chapman-Nisar A, Naeche N, Townsend E, Slovak P, Youth O, Creswell C, Fonagy P, Arseneault L, Lloyd E, De Alcantara Mendes J, Holter C, Jirotka M, Lazar Z, Patalay P, Kelly Y, Kandola A, Sonuga-Barke E, Livingstone S, Kostryka-Allchorne K, Bourgaize J, Stoilova M, O’Connor R, Auer D, Lee S, Jawahar N, Etherson M, Greenhalgh C, Sayal K, Warren J, Wanniarachchi V, Glover K, Stallard P, Hall C, Lucassen M, Merry S, Stasiak K, Babbage C, Khan K, Parker A, Lockwood J, Gregory J, Nielsen E, Vallejos E, Woodcock R, Doherty S, Willingham L. Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial. BMJ Open 2024, 14: e079801. PMID: 38195171, PMCID: PMC10806609, DOI: 10.1136/bmjopen-2023-079801.Peer-Reviewed Original ResearchConceptsSelf-harm ideationSelf-harmEmotion dysregulationEmotion regulationRandomised controlled trialsWaitlist controlEnhance emotion regulationExperiences of self-harmSocially assistive robotsSelf-Harm QuestionnaireSelf-harm thoughtsControlled trialsPeer-reviewed open access journalsLGBTQ+ youthPeople’s own viewsAssistive robotsControl participantsIntervention participantsAcceptable interventionSemistructured interviewsLinear mixed modelsPreliminary evidenceEthical approvalKing's College LondonSecondary outcomesBrief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression
Lisk S, James K, Shearer J, Byford S, Stallard P, Deighton J, Saunders D, Yarrum J, Fonagy P, Weaver T, Sclare I, Day C, Evans C, Carter B, Brown J. Brief Educational Workshops in Secondary Schools Trial (BESST): a cluster randomised controlled trial. Secondary analysis in those with elevated symptoms of depression. BMJ Mental Health 2024, 27: e301192. PMID: 39209761, PMCID: PMC11367360, DOI: 10.1136/bmjment-2024-301192.Peer-Reviewed Original ResearchConceptsTreatment-as-usualCluster randomised controlled trialNational Health ServiceElevated symptoms of depressionQuality-adjusted life yearsElevated depressive symptomsSymptoms of depressionRandomised controlled trialsDepressive symptomsSchools TrialElevated symptomsEducational workshopsIntention-to-treatSecondary analysisPersonal Social Services perspectiveControlled trialsMultilevel linear regressionSocial Services perspectiveSchool-based interventionsCost-effectiveIntention-to-treat analysisOutcomes of participantsHealth servicesIncremental cost-effectiveness ratioClinically meaningful effect
2023
The online world as a means of connection and disconnection during the COVID-19 pandemic: A test of the interpersonal-connections-behaviour framework
Tibber M, Milne G, Fonagy P, Dekker T. The online world as a means of connection and disconnection during the COVID-19 pandemic: A test of the interpersonal-connections-behaviour framework. Journal Of Affective Disorders 2023, 347: 533-540. PMID: 38070743, DOI: 10.1016/j.jad.2023.12.006.Peer-Reviewed Original ResearchConceptsAssociated with poor mental healthPoor mental healthMental healthMental health risksSample of UK adultsSocial comparisonCross-sectional samplePeriod of social isolationIndividual-level moderatorsSocial isolationDirection of causalityClinical perspectiveItem questionsLonelinessLongitudinal analysisOnline socialisationUK adultsHigher levelsAnxietyDepressionDisconnectionHealthModeratelyItemsCOVID-19 pandemicBeyond Mentalizing: Epistemic Trust and the Transmission of Culture
Fonagy P, Allison E. Beyond Mentalizing: Epistemic Trust and the Transmission of Culture. The Psychoanalytic Quarterly 2023, 92: 599-640. PMID: 38095858, DOI: 10.1080/00332828.2023.2290023.Peer-Reviewed Original ResearchConceptsEpistemic trustCultural transmissionInterpersonal originsInterpersonal processesPsychological stateExperience of trustMentalizingPsychic changeLifelong impactPsychoanalytic processEssential humanityHuman cultureClinical implicationsTransmission of cultureTrustHuman beingsHelplessnessPsychoanalysis
2011
Get them before they get you: Trust, trustworthiness, and social cognition in boys with and without externalizing behavior problems
Sharp C, Carolyn H, Fonagy P. Get them before they get you: Trust, trustworthiness, and social cognition in boys with and without externalizing behavior problems. Development And Psychopathology 2011, 23: 647-658. PMID: 23786702, DOI: 10.1017/s0954579410000003.Peer-Reviewed Original Research
2009
A cluster randomized controlled trial of child‐focused psychiatric consultation and a school systems‐focused intervention to reduce aggression
Fonagy P, Twemlow SW, Vernberg EM, Nelson JM, Dill EJ, Little TD, Sargent JA. A cluster randomized controlled trial of child‐focused psychiatric consultation and a school systems‐focused intervention to reduce aggression. Journal Of Child Psychology And Psychiatry 2009, 50: 607-616. PMID: 19207633, DOI: 10.1111/j.1469-7610.2008.02025.x.Peer-Reviewed Original ResearchConceptsPsychiatric consultationSchool-based anti-bullying programsPercent of childrenTrial of effectivenessSystem-focused interventionsTAU conditionOutcome measuresActive interventionSignificant decreaseTrialsInterventionBehavioral changesSchool childrenChildrenAnti-bullying programsElementary school childrenStudy conditionsConsultationDisturbed childrenSchool-wide interventionsYearsLegitimacy of aggression
2004
Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data
Whittington CJ, Kendall T, Fonagy P, Cottrell D, Cotgrove A, Boddington E. Selective serotonin reuptake inhibitors in childhood depression: systematic review of published versus unpublished data. The Lancet 2004, 363: 1341-1345. PMID: 15110490, DOI: 10.1016/s0140-6736(04)16043-1.Peer-Reviewed Original ResearchConceptsSelective serotonin reuptake inhibitorsRisk-benefit profileFavorable risk-benefit profileSerotonin reuptake inhibitorsPeer-reviewed journalsAdverse eventsReuptake inhibitorsPositive risk-benefit profileUnfavourable risk-benefit profileTrial of sertralineSerious adverse eventsDiscontinuation of treatmentTreatment of depressionTrial of paroxetineDepressive symptom scoresSafety of medicinesClinical guideline developmentUnpublished dataSuicide-related behaviorsUnpublished trialsSymptom scoresFollowing outcomesGuideline developmentIntervention studiesSystematic review
2001
Treatment of Borderline Personality Disorder With Psychoanalytically Oriented Partial Hospitalization: An 18-Month Follow-Up
Bateman A, Fonagy P. Treatment of Borderline Personality Disorder With Psychoanalytically Oriented Partial Hospitalization: An 18-Month Follow-Up. American Journal Of Psychiatry 2001, 158: 36-42. PMID: 11136631, DOI: 10.1176/appi.ajp.158.1.36.Peer-Reviewed Original ResearchConceptsStandard psychiatric carePartial hospitalization programBorderline personality disorderPsychiatric careHospitalization programPartial hospitalizationPersonality disorderStandard psychiatric treatmentGeneral symptom distressInpatient admissionsPrevious randomizedSymptom distressService utilizationOutcome measuresTreatment phasePsychiatric treatmentPatientsSuicide attemptsHospitalizationFollowSelf-report measuresOriginal studyCareDisordersTreatment