2024
Post-traumatic stress disorder symptoms following exposure to acute psychological trauma in children aged 8–16 years in South Africa: protocol for the Sinethemba longitudinal study
Sharp T, Chideya Y, Giuliani A, Hunt X, Tomlinson M, Seedat S, Creswell C, Fearon P, Hamilton-Giachritsis C, Hiller R, Meiser-Stedman R, Du Toit S, Stewart J, Halligan S. Post-traumatic stress disorder symptoms following exposure to acute psychological trauma in children aged 8–16 years in South Africa: protocol for the Sinethemba longitudinal study. BMJ Open 2024, 14: e085129. PMID: 38991675, DOI: 10.1136/bmjopen-2024-085129.Peer-Reviewed Original ResearchConceptsMental health outcomesPost-traumatic stress disorderChildren aged 8Caregiver supportHealth outcomesAssociation of psychosocial factorsAdverse mental health outcomesAged 8Traumatic eventsChildren’s post-traumatic stress disorderDepartment of HealthMiddle-income countriesTrauma-related mental healthPsychological risk factorsHigh-income countriesStress disorder symptomsFollow-up assessmentPost-traumatic stress disorder symptomsCape TownMotor vehicle accidentsHealthcare clinicsPsychosocial factorsMental healthPsychological recoveryEthical approvalImplementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya—individually randomised superiority trial
Fonagy P, Chammay R, Ngunu C, Kumar M, Verdeli L, Allison E, Anani G, Fearon P, Fouad F, Hoare Z, Koyio L, Moore H, Nyandigisi A, Pilling S, Sender H, Skordis J, Evans R, Jaoude G, Madeghe B, Maradian S, O’Donnell C, Simes E, Truscott A, Wambua G, Yator O. Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya—individually randomised superiority trial. Trials 2024, 25: 217. PMID: 38532432, PMCID: PMC10964704, DOI: 10.1186/s13063-024-08039-3.Peer-Reviewed Original ResearchConceptsPostnatal depressionInterpersonal psychotherapyChild developmental outcomesMulti-site randomised controlled trialWomen's mental health needsStandard careEfficacy of interpersonal psychotherapyMaternal postnatal depressionMental health needsMental health concernsMiddle-income countriesRandomised controlled trialsDevelopmental outcomesHigh-income countriesAntenatal servicesChildbearing womenMother-child bondingRandomised superiority trialChildren's developmental progressHealth needsOffspring of womenMaternal depressionCommunity settingsLMIC contextsInterpersonal therapyCommentary: Health anxiety in youth during ‘COVID’ – some thoughts prompted by Rask et al. (2024)
Sonuga‐Barke E, Fearon P. Commentary: Health anxiety in youth during ‘COVID’ – some thoughts prompted by Rask et al. (2024). Journal Of Child Psychology And Psychiatry 2024, 65: 431-434. PMID: 38415840, DOI: 10.1111/jcpp.13973.Peer-Reviewed Original ResearchTrial protocol for the Building Resilience through Socio-Emotional Training (ReSET) programme: a cluster randomised controlled trial of a new transdiagnostic preventative intervention for adolescents
Viding E, Lloyd A, Law R, Martin P, Lucas L, Wu T, Steinbeis N, Midgley N, Veenstra R, Smith J, Ly L, Bird G, Murphy J, Plans D, Munafo M, Penton-Voak I, Deighton J, Richards K, Richards M, Fearon P. Trial protocol for the Building Resilience through Socio-Emotional Training (ReSET) programme: a cluster randomised controlled trial of a new transdiagnostic preventative intervention for adolescents. Trials 2024, 25: 143. PMID: 38395922, PMCID: PMC10885387, DOI: 10.1186/s13063-024-07931-2.Peer-Reviewed Original ResearchConceptsMental health problemsPost-interventionPreventive interventionsCluster randomised controlled trialPrevent mental health problemsHealth problemsRates of mental health disordersCluster-randomised designCommunication skills trainingTransdiagnostic preventive interventionMental health disordersSchool year levelRandomised controlled trialsSubgroup of participantsDiscussionThis projectScalable interventionsEmotional processingFollow-upMental wellbeingWeekly sessionsFocus groupsHealth disordersGroup-basedAssessed pre-Individual sessions
2023
Cohort Profile Update: The Neuroscience in Psychiatry Network (NSPN) 2400 cohort during the COVID-19 pandemic
Wiedemann A, Bhatti J, Hook R, Neufeld S, Bullmore E, Dolan R, Goodyer I, Fonagy P, Jones P, Chamberlain S, Moutoussis M, Hauser T, Neufeld S, Romero-Garcia R, St Clair M, Vértes P, Whitaker K, Inkster B, Prabhu G, Ooi C, Toseeb U, Widmer B, Bhatti J, Villis L, Alrumaithi A, Birt S, Bowler A, Cleridou K, Dadabhoy H, Davies E, Firkins A, Granville S, Harding E, Hopkins A, Isaacs D, King J, Kokorikou D, Maurice C, McIntosh C, Memarzia J, Mills H, O’Donnell C, Pantaleone S, Scott J, Kiddle B, Polek E, Fearon P, Suckling J, van Harmelen A, Kievit R, Bethlehem R, Dolan R, Fonagy P, Goodyer I, Bullmore E, Chamberlain S, Jones P. Cohort Profile Update: The Neuroscience in Psychiatry Network (NSPN) 2400 cohort during the COVID-19 pandemic. International Journal Of Epidemiology 2023, 52: e315-e323. PMID: 37418602, PMCID: PMC10749753, DOI: 10.1093/ije/dyad095.Peer-Reviewed Original ResearchRoutinely used interventions to improve attachment in infants and young children: a national survey and two systematic reviews
Wright B, Fearon P, Garside M, Tsappis E, Amoah E, Glaser D, Allgar V, Minnis H, Woolgar M, Churchill R, McMillan D, Fonagy P, O'Sullivan A, McHale M. Routinely used interventions to improve attachment in infants and young children: a national survey and two systematic reviews. Health Technology Assessment 2023, 27: 1-226. PMID: 36722615, PMCID: PMC9900465, DOI: 10.3310/ivcn8847.Peer-Reviewed Original ResearchConceptsSystematic reviewEvidence baseNIHR Journals Library websiteHealth Technology Assessment programmeUK servicesFurther project informationTechnology Assessment programmeParenting interventionsLimited evidence baseWeak evidence baseStrong evidence baseExpert reference groupTrial evidenceReview 2Clinical practiceRoutine practiceReference groupNumerous interventionsInterventionNational InstituteYoung childrenRobust researchAttachment interventionsSecond reviewHealth technologies
2022
Neural correlates of face familiarity in institutionalised children and links to attachment disordered behaviour
Oliveira P, Fearon P, Belsky J, Mesquita A, Sampaio A, Pinal D, Soares I. Neural correlates of face familiarity in institutionalised children and links to attachment disordered behaviour. Journal Of Child Psychology And Psychiatry 2022, 64: 736-746. PMID: 36457167, DOI: 10.1111/jcpp.13728.Peer-Reviewed Original ResearchConceptsEvent-related potentialsReactive attachment disorderStranger's faceNeural correlatesNeural processingP400 amplitudeChildren's neural processingBrain-based markersSocial engagement disorderCaregiver's faceFace familiarityFace processingERP measuresAttachment problemsAttachment disorderRAD symptomsSmaller P1Early maltreatmentNeurobiological effectsPortuguese childrenHigher childCaregiver ratioCurrent studyBehavioral patternsChildrenMeasuring Antenatal Depressive Symptoms Across the World: A Validation and Cross-Country Invariance Analysis of the Patient Health Questionnaire-9 (PHQ-9) in Eight Diverse Low-Resource Settings
Murray A, Hemady C, Do H, Dunne M, Foley S, Osafo J, Sikander S, Madrid B, Baban A, Taut D, Ward C, Fernando A, Van Thang V, Eisner M, Hughes C, Fearon P, Valdebenito S, Tomlinson M, Pathmeswaran A, Walker S. Measuring Antenatal Depressive Symptoms Across the World: A Validation and Cross-Country Invariance Analysis of the Patient Health Questionnaire-9 (PHQ-9) in Eight Diverse Low-Resource Settings. Psychological Assessment 2022, 34: 993-1007. PMID: 36227303, DOI: 10.1037/pas0001154.Peer-Reviewed Original ResearchA modified video-feedback intervention for carers of foster children aged 6 years and under with reactive attachment disorder: a feasibility study and pilot RCT
Oliveira P, Stevens E, Barge L, Comyn J, Langley K, Ramchandani P, Wright B, Woolgar M, Kennedy E, Byford S, Shearer J, Scott S, Barlow J, Glaser D, Senior R, Fonagy P, Fearon P. A modified video-feedback intervention for carers of foster children aged 6 years and under with reactive attachment disorder: a feasibility study and pilot RCT. Health Technology Assessment 2022, 26: 1-106. PMID: 35959710, PMCID: PMC9421559, DOI: 10.3310/sliz1119.Peer-Reviewed Original ResearchConceptsVideo-feedback InterventionCase seriesMAIN OUTCOMEReactive attachment disorderNIHR Journals Library websiteHealth Technology Assessment programmeNew interventionsAdolescent mental health servicesFuture full-scale trialFurther project informationSmall case seriesTreatment manualWide inclusion criteriaTechnology Assessment programmeMental health servicesTarget sample sizeEffective treatment approachEvidence-based interventionsAttachment disorderLarge-scale trialsHealth service practitionersMental health professionalsTreatment completenessUsual carePilot RCTHeritability of Psychological Traits and Developmental Milestones in Infancy
Austerberry C, Mateen M, Fearon P, Ronald A. Heritability of Psychological Traits and Developmental Milestones in Infancy. JAMA Network Open 2022, 5: e2227887. PMID: 35994288, PMCID: PMC9396365, DOI: 10.1001/jamanetworkopen.2022.27887.Peer-Reviewed Original ResearchAssociations Between ADHD Symptoms and Maternal and Birth Outcomes: An Exploratory Analysis in a Multi-Country Cohort of Expectant Mothers
Murray A, Taut D, Baban A, Hemady C, Walker S, Osafo J, Sikander S, Tomlinson M, Du Toit S, Marlow M, Ward C, Fernando A, Madrid B, Van Thang V, Tuyen H, Dunne M, Hughes C, Fearon P, Valdebenito S, Eisner M. Associations Between ADHD Symptoms and Maternal and Birth Outcomes: An Exploratory Analysis in a Multi-Country Cohort of Expectant Mothers. Journal Of Attention Disorders 2022, 26: 1882-1894. PMID: 35815439, PMCID: PMC9597155, DOI: 10.1177/10870547221105064.Peer-Reviewed Original ResearchConceptsADHD symptomsSignificant associationLongitudinal birth cohort studyLow birth weightBirth cohort studyGreater mental health supportLow social supportMental health difficultiesMental health supportCohort studyBirth outcomesPremature birthThird trimesterRegular screeningBirth weightUnplanned pregnancyTobacco useDepressive symptomsExpectant mothersPregnancyFetal developmentUnwanted pregnancyHealth difficultiesSymptomsAlcohol useAdolescent development of multiscale structural wiring and functional interactions in the human connectome
Park B, Paquola C, Bethlehem R, Benkarim O, Consortium N, Mišić B, Smallwood J, Bullmore E, Bernhardt B, Bullmore E, Dolan R, Goodyer I, Fonagy P, Jones P, Moutoussis M, Hauser T, Neufeld S, Romero-Garcia R, St Clair M, Vértes P, Whitaker K, Inkster B, Prabhu G, Ooi C, Toseeb U, Widmer B, Bhatti J, Villis L, Alrumaithi A, Birt S, Bowler A, Cleridou K, Dadabhoy H, Davies E, Firkins A, Granville S, Harding E, Hopkins A, Isaacs D, King J, Kokorikou D, Maurice C, McIntosh C, Memarzia J, Mills H, O’Donnell C, Pantaleone S, Scott J, Kiddle B, Polek E, Fearon P, Suckling J, van Harmelen A, Kievit R, Chamberlain S. Adolescent development of multiscale structural wiring and functional interactions in the human connectome. Proceedings Of The National Academy Of Sciences Of The United States Of America 2022, 119: e2116673119. PMID: 35776541, PMCID: PMC9271154, DOI: 10.1073/pnas.2116673119.Peer-Reviewed Original ResearchConceptsAdolescent developmentFunctional brain network developmentResting-state functional MRI measuresAccelerated longitudinal cohortBrain network developmentDefault mode networkFunctional MRI measuresStructural wiringHuman brain structureStructure-function couplingAge-related changesMode networkSame participantsHuman connectomeCortical wiringBrain structuresLongitudinal analysisCross-sectional analysisLongitudinal changesFunctional hierarchyMRI featuresLongitudinal cohortMRI measuresWhite matterFunctional interactionPatterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis
Hemady C, Speyer L, Murray A, Brown R, Meinck F, Fry D, Do H, Sikander S, Madrid B, Fernando A, Walker S, Dunne M, Foley S, Hughes C, Osafo J, Baban A, Taut D, Ward C, Van Thang V, Fearon P, Tomlinson M, Valdebenito S, Eisner M. Patterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis. BMC Pregnancy And Childbirth 2022, 22: 505. PMID: 35733125, PMCID: PMC9215006, DOI: 10.1186/s12884-022-04839-0.Peer-Reviewed Original ResearchConceptsPrenatal substance usePoor infant outcomesAdverse childhood experiencesInfant outcomesHousehold dysfunctionSubstance useLatent class analysisPrenatal drug useMother-infant dyadsLow-risk classMultilevel logistic regressionChildhood experiencesAntenatal supportHigh-risk classMiddle-income countriesStudy cohortLow birthweightPerinatal periodDrug useConclusionOur resultsChildhood adversityClass analysisLogistic regressionViolence exposureDysfunctionPerceived stress during the prenatal period: assessing measurement invariance of the Perceived Stress Scale (PSS-10) across cultures and birth parity
Katus L, Foley S, Murray A, Luong-Thanh B, Taut D, Baban A, Madrid B, Fernando A, Sikander S, Ward C, Osafo J, Marlow M, Du Toit S, Walker S, Van Vo T, Fearon P, Valdebenito S, Eisner M, Hughes C. Perceived stress during the prenatal period: assessing measurement invariance of the Perceived Stress Scale (PSS-10) across cultures and birth parity. Archives Of Women's Mental Health 2022, 25: 633-640. PMID: 35420323, PMCID: PMC9072510, DOI: 10.1007/s00737-022-01229-5.Peer-Reviewed Original ResearchCommentary: Are complex parenting interventions less than the sum of their parts? A reflection on Leijten et al. (2022)
Fearon P, Sonuga‐Barke E. Commentary: Are complex parenting interventions less than the sum of their parts? A reflection on Leijten et al. (2022). Journal Of Child Psychology And Psychiatry 2022, 63: 500-502. PMID: 35266553, DOI: 10.1111/jcpp.13596.Peer-Reviewed Original ResearchAdapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): report of a feasibility randomized controlled trial
O’Mahen H, Ramchandani P, King D, Lee-Carbon L, Wilkinson E, Thompson-Booth C, Ericksen J, Milgrom J, Dunkley-Bent J, Halligan S, Fearon P. Adapting and testing a brief intervention to reduce maternal anxiety during pregnancy (ACORN): report of a feasibility randomized controlled trial. BMC Psychiatry 2022, 22: 129. PMID: 35177019, PMCID: PMC8851863, DOI: 10.1186/s12888-022-03737-1.Peer-Reviewed Original ResearchConceptsPregnant individualsBrief interventionPrimary care servicesPublic health benefitsNew brief interventionLarge-scale trialsMaternal prenatal anxietyUsual careIntervention armPrenatal clinicsLevel of anxietyMaternal anxietyTreatment groupsMaternity servicesCare servicesElevated symptomsPrenatal anxietyFurther evaluationMore sessionsHealth benefitsInterventionPregnancyMindfulness exercisesGroup sessionsAnxietyDevelopmental pathways from toddler difficult temperament to child generalized psychopathology and adult functioning
Wu T, Meehan A, Rijlaarsdam J, Maughan B, Fearon P, Barker E. Developmental pathways from toddler difficult temperament to child generalized psychopathology and adult functioning. Journal Of Affective Disorders 2022, 301: 14-22. PMID: 34990631, DOI: 10.1016/j.jad.2022.01.012.Peer-Reviewed Original ResearchConceptsEarly difficult temperamentLate childhood/early adolescenceChildhood/early adolescenceDifficult temperamentMental health symptomsPositive parentingEarly adolescenceChild mental health symptomsDepressive symptomsLater mental health difficultiesRisk community sampleLow-risk community sampleChild mental health problemsImpaired psychosocial functioningMother-child dyadsMental health difficultiesOwn depressive symptomsChild difficult temperamentMental health problemsNegative parentingChildhood/adolescenceGeneral psychopathology factorGeneralized psychopathologyPsychosocial functioningAdult functioning
2021
Editorial: ‘The giant’s shoulders’: understanding Michael Rutter’s impact on science and society
Sonuga‐Barke E, Fearon P, Scott S. Editorial: ‘The giant’s shoulders’: understanding Michael Rutter’s impact on science and society. Journal Of Child Psychology And Psychiatry 2021, 63: 1-3. PMID: 34957560, DOI: 10.1111/jcpp.13558.Peer-Reviewed Original ResearchIntranasal oxytocin administration improves mood in new mothers with moderate low mood but not in mothers with elevated symptoms of postnatal depression: A randomised controlled trial
Lindley Baron-Cohen K, Feldman R, Fearon P, Fonagy P. Intranasal oxytocin administration improves mood in new mothers with moderate low mood but not in mothers with elevated symptoms of postnatal depression: A randomised controlled trial. Journal Of Affective Disorders 2021, 300: 358-365. PMID: 34843839, DOI: 10.1016/j.jad.2021.11.062.Peer-Reviewed Original ResearchConceptsEdinburgh Postnatal Depression ScalePostnatal depressionOT administrationNew mothersLow moodPostnatal Depression ScaleCross-over designAntidepressant effectsMonths postpartumSevere scoresPND casesPND scoresSub-clinical levelsTreatment benefitDepression ScaleMood spectrumClinical diagnosisElevated symptomsAdministrationMood scoresMothersNegative moodWomenNeuropeptide hormoneDepressionEditorial: Do lockdowns scar? Three putative mechanisms through which COVID‐19 mitigation policies could cause long‐term harm to young people's mental health
Sonuga‐Barke E, Fearon P. Editorial: Do lockdowns scar? Three putative mechanisms through which COVID‐19 mitigation policies could cause long‐term harm to young people's mental health. Journal Of Child Psychology And Psychiatry 2021, 62: 1375-1378. PMID: 34806768, PMCID: PMC9011706, DOI: 10.1111/jcpp.13537.Peer-Reviewed Original ResearchConceptsYoung people's mental healthPeople's mental healthMental healthLong-term effectsPutative mechanismsHigh-risk settingsParent mental healthPre-existing conditionsUse of lockdownsLong-term harmCOVID-19 mitigation policiesNegative psychological impactParticular riskCOVID-19Social isolationPsychological impactVulnerable individualsHealthEarly predictionDirect effectSuch long-term effectsIndirect effectsLockdownHarmPersons