Humanized dopamine D4.7 receptor male mice display risk‐taking behavior and deficits of social recognition and working memory in light/dark‐dependent manner
Alachkar A, Phan A, Dabbous T, Alhassen S, Alhassen W, Reynolds B, Rubinstein M, Ferré S, Civelli O. Humanized dopamine D4.7 receptor male mice display risk‐taking behavior and deficits of social recognition and working memory in light/dark‐dependent manner. Journal Of Neuroscience Research 2024, 102: e25299. PMID: 38361407, PMCID: PMC11503891, DOI: 10.1002/jnr.25299.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAttention Deficit Disorder with HyperactivityDopamineHumansMaleMemory DisordersMemory, Short-TermMiceReceptors, Dopamine D4Risk-TakingConceptsPsychiatric disordersBehavioral phenotypesImpaired social recognition memoryEtiology of psychiatric disordersAttention-deficit hyperactivity disorderDopamine D<sub>4</sub> receptor (DWorking memory deficitsSocial recognition memoryDark phaseRisk-taking behaviorRecognition memoryWorking memoryMemory deficitsR miceIncreased risk behaviorSocial recognitionSpecific behaviorsBehavioral featuresDisordersMale miceDopaminePotential causal relationshipRisk behaviorsLight phaseDeficits