2023
A systematic review of childhood maltreatment and resting state functional connectivity
Gerin M, Viding E, Herringa R, Russell J, McCrory E. A systematic review of childhood maltreatment and resting state functional connectivity. Developmental Cognitive Neuroscience 2023, 64: 101322. PMID: 37952287, PMCID: PMC10665826, DOI: 10.1016/j.dcn.2023.101322.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityAnterior cingulate cortexFunctional connectivityCingulate cortexChildhood maltreatmentAltered functional connectivityState functional connectivityDorsal anterior cingulate cortexNegative psychiatric outcomesVentral anterior cingulate cortexDorsolateral prefrontal cortexRsFC alterationsAltered connectivityInclusion criteriaAmygdala connectivityNineteen studiesPsychiatric outcomesFuture symptomsSystematic reviewBrain regionsClinical disordersBrain circuitsAnterior insulaPrefrontal cortexMaltreatment exposure
2018
An fMRI investigation of empathic processing in boys with conduct problems and varying levels of callous-unemotional traits
Sethi A, O'Nions E, McCrory E, Bird G, Viding E. An fMRI investigation of empathic processing in boys with conduct problems and varying levels of callous-unemotional traits. NeuroImage Clinical 2018, 18: 298-304. PMID: 29876250, PMCID: PMC5987797, DOI: 10.1016/j.nicl.2018.01.027.Peer-Reviewed Original ResearchConceptsCP/HCUMedial prefrontal cortexCallous-unemotional traitsConduct problemsOwn emotionsAnterior cingulate cortexAnterior insulaEmpathic processingAffective experienceConjunction analysisACC/medial prefrontal cortexBrain areasBayes factor analysisEmpathy deficitsFMRI investigationTD groupNeural responsesConjunction effectOne's feelingsLess empathyEmotionsPrefrontal cortexNeutral scenarioCingulate cortexOccipital cortex
2017
The Neuroscience and Genetics of Childhood Maltreatment
McCrory E, Puetz V, Viding E. The Neuroscience and Genetics of Childhood Maltreatment. 2017, 187-194. DOI: 10.1002/9781119170235.ch22.Peer-Reviewed Original ResearchPost-traumatic stress disorderChildhood maltreatmentHigher cognitive abilitiesStudy of childrenCognitive abilitiesEmotional processesInter-hemispheric communicationBody of researchAspects of behaviorStress disorderPrefrontal cortexSmaller hippocampal volumesBrain functionMaltreatmentBrain structuresSubcortical regionsNeural structuresHippocampal volumeCorpus callosumHost of processesWhite matter structuresLargest white matter structureNumber of studiesMatter structuresEmotions
2015
Childhood Trauma and Neural Responses to Personalized Stress, Favorite-Food and Neutral-Relaxing Cues in Adolescents
Elsey J, Coates A, Lacadie CM, McCrory EJ, Sinha R, Mayes LC, Potenza MN. Childhood Trauma and Neural Responses to Personalized Stress, Favorite-Food and Neutral-Relaxing Cues in Adolescents. Neuropsychopharmacology 2015, 40: 1580-1589. PMID: 25567424, PMCID: PMC4915266, DOI: 10.1038/npp.2015.6.Peer-Reviewed Original ResearchConceptsChildhood traumaPersonalized stressSubjective anxietyFavorite-food cuesFunctional magnetic resonance imagingPhysical health outcomesCortico-limbic circuitryNeural correlatesMotivational stateTrauma exposureNeural responsesFunctional neuroimagingPrefrontal cortexStress cuesAnterior cingulateEmotional disturbanceCerebellar regionsCuesGroup differencesRisky behaviorsBrain regionsAdolescentsSubcortical structuresAnxietyIncreased activation
2013
Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability?
Kelly P, Viding E, Wallace G, Schaer M, De Brito S, Robustelli B, McCrory E. Cortical Thickness, Surface Area, and Gyrification Abnormalities in Children Exposed to Maltreatment: Neural Markers of Vulnerability? Biological Psychiatry 2013, 74: 845-852. PMID: 23954109, DOI: 10.1016/j.biopsych.2013.06.020.Peer-Reviewed Original ResearchConceptsCortical thicknessLingual gyrusAnterior cingulateLeft middle temporal areaSuperior frontal gyrusBrain volume differencesAtypical neural structureCortical surface areaMiddle temporal areaPrevious neuroimaging studiesGyrification abnormalitiesTemporal lobePsychiatric disordersLocal gyrificationPsychiatric riskHistory of abuseStructural abnormalitiesTemporal areaClinical disordersBiological markersOrbitofrontal cortexPrefrontal cortexBrain structuresGyrusNeuroimaging studies
2012
Reduced orbitofrontal and temporal grey matter in a community sample of maltreated children
De Brito S, Viding E, Sebastian C, Kelly P, Mechelli A, Maris H, McCrory E. Reduced orbitofrontal and temporal grey matter in a community sample of maltreated children. Journal Of Child Psychology And Psychiatry 2012, 54: 105-112. PMID: 22880630, DOI: 10.1111/j.1469-7610.2012.02597.x.Peer-Reviewed Original ResearchConceptsMedial orbitofrontal cortexPsychiatric disordersMiddle temporal gyrusOrbitofrontal cortexTemporal lobeGray matterTemporal gyrusConcurrent psychiatric disordersTemporal gray matterGray matter volumeVoxel-based morphometryCommunity sampleLeft middle temporal gyrusAtypical neural structurePrevious neuroimaging studiesNeurobiological risk factorsRisk factorsLevel of anxietyMatter volumePosttraumatic stress symptomsPsychiatric vulnerabilityConcurrent anxietyPrefrontal cortexCortexNeuroimaging studies
2010
Research Review: The neurobiology and genetics of maltreatment and adversity
McCrory E, De Brito SA, Viding E. Research Review: The neurobiology and genetics of maltreatment and adversity. Journal Of Child Psychology And Psychiatry 2010, 51: 1079-1095. PMID: 20546078, DOI: 10.1111/j.1469-7610.2010.02271.x.Peer-Reviewed Original ResearchConceptsChildhood maltreatmentEarly adversityFunctional brain differencesIndividual's genetic makeAdrenal axis stress responseAtypical developmentEmotional developmentNeurobiological developmentAtypical activationNeurobiological mechanismsBrain differencesPrefrontal cortexPsychiatric vulnerabilityEnvironmental experiencesAdversityEnvironmental adversityBrain regionsEarly stressMaltreatmentNeuroendocrine findingsChildrenAdultsCorpus callosumGenetic makeHuman studies